Lamirax tablets

Lamirax

  • Active Ingredient: Lamotrigine
  • 200 mg, 100 mg, 50 mg, 25 mg
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What is Lamirax?

The active ingredient of Lamirax brand is lamotrigine. Lamotrigine is an anti-epileptic medication, also called an anticonvulsant. Lamotrigine tablets, USP are supplied for oral administration as 25 mg, 100 mg, 150 mg or 200 mg tablets. Each tablet contains the labeled amount of Lamotrigine and the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, pregelatinized starch (corn) and sodium lauryl sulfate. In addition, the 200 mg tablets contain D&C Yellow No. 10 Aluminum Lake and FD&C Blue No. 1 Aluminum Lake. Meets USP Dissolution Test 3.

Used for

Lamirax is used to treat diseases such as: Anxiety, Bipolar Disorder, Borderline Personality Disorder, Cyclothymic Disorder, Depression, Epilepsy, Migraine Prevention, Post Traumatic Stress Disorder, Restless Legs Syndrome, Schizoaffective Disorder, Seizure Prevention.

Side Effect

Possible side effects of Lamirax include: lightheadedness; pale skin; dark-colored urine; headache (severe); mask-like face; loss of strength.

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4. How and when to take it

Lamirax is a prescription medicine. It's important to take it as advised by your doctor.

Common Side Effects of Lamictal (Lamirax):

Let your doctor know if any of these side effects persist or get worse.

  • Nausea
  • Dizziness
  • Drowsiness
  • Headache
  • Changes in menstrual periods
  • Back pain
  • Insomnia (trouble sleeping)
  • Blurred or double vision
  • Shaking (tremors)
  • Vomiting
  • Upset stomach
  • Feeling tired
  • Runny nose
  • Sore throat

Q: Will the generic form of Lamictal (Lamirax) work as well for depression?

A: The generic form of Lamictal, Lamirax, should work just as well as the brand name. The FDA requires that a generic have the exact same active ingredient as the brand. The generic must prove to the FDA is just as safe and just as effective as the brand. The inactive ingredients are what may be changed. Therefore, in most cases, studies show generics will work as well as the brand. You may also find helpful information on depression and medications at //www.everydayhealth.com/depression/guide/, //www.everydayhealth.com/drugs/.

Dosage warnings

Your starting dosage of Lamirax should not be higher than the recommended starting dosage. Also, your dosage should not be increased too quickly. If your dosage is too high or increased too quickly, you’re at higher risk of a serious or life-threatening skin rash.

If you’re taking this drug to treat seizures and are supposed to stop taking it, your doctor will slowly lower your dosage over at least two weeks. If your dosage isn’t slowly lowered and tapered off, you will be at increased risk of having more seizures.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Lamirax oral tablet is used for long-term treatment. It comes with risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: If you take this drug to treat seizures, stopping the drug suddenly or not taking it at all may cause serious problems. These include an increased risk of seizures. They also include risk of a condition called status epilepticus (SE). With SE, short or long seizures occur for 30 minutes or more. SE is a medical emergency.

If you take this drug to treat bipolar disorder, stopping the drug suddenly or not taking it at all may cause serious problems. Your mood or behavior may get worse. You may need to be admitted to the hospital.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. In order for this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of the drug in your body. If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take it as soon as you remember. If you remember just a few hours before the time for your next dose, only take one dose. Never try to catch up by taking two tablets at once. This could result in dangerous side effects.

How to tell if the drug is working: If you take this drug to treat seizures, you should have fewer seizures, or less severe seizures. Be aware that you may not feel the full effect of this drug for several weeks.

If you take this drug to treat bipolar disorder, you should have fewer episodes of extreme moods. Be aware that you may not feel the full effect of this drug for several weeks.

Keep these considerations in mind if your doctor prescribes Lamirax for you.

What Is Lamictal (Lamirax)?

Lamictal is the brand name of Lamirax, an anti-epileptic medication that belongs to a class of drugs known as anticonvulsants.

Lamictal is used alone or in combination with other drugs to treat seizures in adults and children with epilepsy.

It's also used to treat Lennox-Gastaut syndrome, an extreme form of epilepsy that causes seizures and often causes developmental delays in children.

In addition, Lamictal is commonly prescribed to adults with bipolar disorder (manic depression) to delay episodes of depression and mania. (Mania is defined as frenzied or abnormally excited moods).

Lamictal is also prescribed off-label to treat clinical depression and migraine headaches.

The FDA first approved Lamictal in 1994 as an anti-seizure medication. Approval to use the drug in the treatment of bipolar disorder was given in 2003.

Lamictal is manufactured by GlaxoSmithKline.

Your age impacts the type and dose of Lamictal you can take. The immediate-release form of Lamictal is given to children as young as age 2, but only in addition to other seizure medications.

It's not given as a stand-alone medication in someone who is younger than 16.

The extended-release form, Lamictal XR, is only prescribed to patients 13 years old and older.

Drug forms and strengths

Generic: Lamirax

  • Form: oral tablet
  • Strengths: 25 mg, 50 mg, 100 mg, 150 mg, 200 mg
  • Form: chewable tablet
  • Strengths: 2 mg, 5 mg, 25 mg
  • Form: orally disintegrating tablet (can be dissolved on the tongue)
  • Strengths: 25 mg, 50 mg, 100 mg, 200 mg
  • Form: extended-release tablet
  • Strengths: 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, 300 mg

Brand: Lamictal

  • Form: oral tablet
  • Strengths: 25 mg, 100 mg, 150 mg, 200 mg

Brand: Lamictal CD

  • Form: chewable tablet
  • Strengths: 2 mg, 5 mg, 25 mg

Brand: Lamictal ODT

  • Form: orally disintegrating tablet (can be dissolved on the tongue)
  • Strengths: 25 mg, 50 mg, 100 mg, 200 mg

Brand: Lamictal XR

  • Form: extended-release tablet
  • Strengths: 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, 300 mg

Q: Can Lamictal cause strange dreams to occur and waking up in the middle of the night?

A: Lamictal (Lamirax) is an anti-seizure medicine that is used to treat bipolar disorder. According to the package insert, the most common side effects of Lamictal are headache, rash and itching, dizziness, diarrhea, and abnormal dreams. This is not a complete list of the side effects associated with Lamictal. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Some other possible causes of nightmares include having a late-night snack, which can increase metabolism and brain activity; withdrawal from medications and substances such as alcohol; sleep deprivation or sleep disorders; and psychological disorders such as anxiety and depression. If you think a drug you are taking is causing bad dreams, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. Tell your health care provider about any negative side effects from prescription drugs. You can also report them to the U.S. Food and Drug Administration by visiting https://www.fda.gov/Safety/MedWatch/default.htm or by calling 1-800-FDA-1088. Michelle McDermott, RPh, PharmD

Does Lamirax interact with any medications or other substances?

Certain other drugs can affect the way Lamirax works in your body by decreasing its effectiveness or delaying its excretion from your body. These include hormonal birth control methods, hormone treatments, seizure medications such as phenobarbital, and valproic acid, which is also used to treat bipolar disorder.

Your doctor will carefully prescribe and monitor your dosage when Lamirax is taken with other treatments. Avoid alcohol, cannabis, and other substances that can increase dizziness or drowsiness while taking Lamirax. To rule out dangerous side effects, discuss all other medications or mind-altering substances you consume with your doctor before taking Lamirax.

One recent British study found that folic acid supplements can cancel out Lamirax’s benefits (Geddes et al., 2016). “No one expected that result, as folic acid usually helps depression, and other medications, like valproate (a mood stabilizer approved for mania associated with bipolar disorder, seizures/epilepsy, and migraine headaches),” says Dr. Aiken. “More research is needed before we can fully trust this result, but until then, we recommend taking Lamirax without any folic acid supplements, including those found in multivitamins. Once you’re doing well on Lamirax, if you decided to add folic acid, watch out for a potential loss of benefits.”

IMPORTANT WARNING:

Lamirax may cause rashes, including serious rashes that may need to be treated in a hospital or cause permanent disability or death. Tell your doctor if you are taking valproic acid (Depakene) or divalproex (Depakote) because taking these medications with Lamirax may increase your risk of developing a serious rash. Also tell your doctor if you have ever developed a rash after taking Lamirax or any other medication for epilepsy or if you are allergic to any medications for epilepsy.

Your doctor will start you on low dose of Lamirax and gradually increase your dose, not more than once every 1 to 2 weeks. You may be more likely to develop a serious rash if you take a higher starting dose or increase your dose faster than your doctor tells you that you should. Your first doses of medication may be packaged in a starter kit that will clearly show you the right amount of medication to take each day during the first 5 weeks of your treatment. This will help you to follow your doctor's instructions as your dose is slowly increased. Be sure to take Lamirax exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Serious rashes usually develop during the first 2 to 8 weeks of treatment with Lamirax, but can develop at any time during treatment. If you develop any of the following symptoms while you are taking Lamirax, call your doctor immediately: rash; blistering or peeling of the skin; hives; itching; or painful sores in your mouth or around your eyes.

Talk to your doctor about the risks of taking Lamirax or of giving Lamirax to your child. Children 2-17 years of age who take Lamirax are more likely to develop serious rashes than adults who take the medication.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Lamirax and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Having epilepsy means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Lamirax is a commonly used medicine. It works by stabilising the electrical activity of your brain, which helps to prevent the seizures from occurring.

Generic Name: Lamirax (la MOE tri jeen)Brand Name: LaMICtal, LaMICtal ODT, LaMICtal XR, Subvenite, . show all 20 brand names LaMICtal CD, LaMICtal Starter Kit (Blue), LaMICtal Starter Kit (Green), LaMICtal Starter Kit (Orange), LaMICtal ODT Patient Titration Kit (Blue), LaMICtal ODT Patient Titration Kit (Orange), LaMICtal ODT Patient Titration Kit (Green), LaMICtal XR Patient Titration Kit (Blue), LaMICtal XR Patient Titration Kit (Orange), LaMICtal XR Patient Titration Kit (Green), LamoTRIgine Starter Kit (Blue), LamoTRIgine Starter Kit (Green), LamoTRIgine Starter Kit (Orange), Subvenite Starter Kit (Blue), Subvenite Starter Kit (Green), Subvenite Starter Kit (Orange)

Medically reviewed by Drugs.com on Oct 8, 2019 – Written by Cerner Multum

Mixing Lamirax with herbal remedies and supplements

There might be a problem taking some herbal remedies and supplements alongside Lamirax, especially ones that can cause rashes, sleepiness or shaking and tremors.

Ask your pharmacist for advice.

How it works

Lamirax belongs to a class of drugs called anticonvulsants or antiepileptic drugs (AEDs). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

For people with epilepsy, this drug reduces the release of a substance in your brain known as glutamate. This action prevents the neurons in your brain from becoming too active. As a result, you may have fewer seizures.

For people with bipolar disorder, this drug may affect certain receptors in your brain that help control your mood. This could decrease the number of mood episodes you have.

Lamirax oral tablet may cause drowsiness. Do not drive, use heavy machinery, or do other dangerous activities until you know how this drug affects you.

Lamirax can also cause other side effects.

How to use Lamirax Tablet

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Lamirax and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor. Swallow the tablets whole since chewing them may leave a bitter taste.

Dosage is based on your medical condition, response to treatment, and use of certain interacting drugs. (See also Drug Interactions section.) For children, the dosage is also based on weight.

It is very important to follow your doctor's dosing instructions exactly. The dose must be increased slowly. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication. Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Also, if you have stopped taking this medication, do not restart Lamirax without consulting your doctor.

Tell your doctor if your condition does not improve or if it worsens.

How to take Lamirax

  • Before you start the treatment, read the manufacturer's printed information leaflet from ins >

Skin rashes

It's common to get a skin rash with Lamirax. Most skin rashes are not serious.

But if you develop a skin rash or redness, tell a doctor straight away, as this can develop into a life-threatening skin condition called Stevens-Johnson syndrome.

Stevens-Johnson syndrome is a rare side effect of Lamirax. It causes flu-like symptoms, followed by a red or purple rash that spreads and forms blisters. The affected skin eventually dies and peels off.

It's more likely to happen in the first 8 weeks of starting Lamirax, or when the dose is increased too quickly.

It can also happen if Lamirax is stopped suddenly for a few days and then restarted at the same dose as before, without reducing the dose and then increasing it slowly again.

Stevens-Johnson syndrome is more common in:

  • children
  • people who developed a rash with a different epilepsy medicine in the past
  • people who are allergic to an antibiotic called trimethoprim
  • people also taking a medicine called sodium valproate

To help prevent the chance of you getting a rash that could be confused with Stevens-Johnson syndrome, it's best to not start any new medicines, foods or products during the first 3 months of treatment with Lamirax.

It's also best to not start Lamirax within 2 weeks of a viral infection, vaccination or rash caused by something else.

What is the dosage for Lamirax?

The dose of immediate release Lamirax for seizures in patients not taking valproic acid (Depakote, Depakote ER, Depakene, Depacon, Stavzor), but taking seizure medications that reduce Lamirax blood levels (for example, phenobarbitol, phenytoin , carbamazepine , primidone) is 50 mg once daily for two weeks, followed by 100 mg daily given in two divided doses for two weeks. Thereafter, the dose is increased by 100 mg daily every 1-2 weeks up to the usual maintenance dose of 300 to 500 mg daily given as a divided dose.

In patients who are taking valproic acid in which it increases blood levels of Lamirax, the initial dose of Lamirax is 25 mg every other day for two weeks, then 25 mg once daily for two weeks. After 4 weeks the dose is slowly increased by 25 to 50 mg per day every one to two weeks until a dose of 100 to 400 mg once daily or divided twice daily is reached. The maintenance dose when using extended release tablets is 200 to 600 mg once daily.

The target dose for treating bipolar disorder is 100 to 400 mg daily.


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