Hexanurat tablets


  • Active Ingredient: Allopurinol
  • 300 mg
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What is Hexanurat?

The active ingredient of Hexanurat brand is allopurinol. Allopurinol reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones. Allopurinol is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d]pyrimidin-4-one. It is a xanthine oxidase inhibitor which is administered orally. Each scored white tablet contains 100 mg Allopurinol and the inactive ingredients colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose and sodium starch glycolate. Each scored orange tablet contains 300 mg Allopurinol and the inactive ingredients colloidal silicon dioxide, FD&C Yellow No. 6 Lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. Its solubility in water at 37В°C is 80 mg/dL and is greater in an alkaline solution.

Used for

Hexanurat is used to treat diseases such as: Calcium Oxalate Calculi with Hyperuricosuria, Cardiothoracic Surgery, Gout, Heart Failure, High Risk Percutaneous Transluminal Angioplasty, Hyperuricemia Secondary to Chemotherapy, Leishmaniasis, Mania, Reactive Perforating Collangenosis, Urinary Tract Stones.

Side Effect

Possible side effects of Hexanurat include: feeling of warmth or heat; large, flat, blue or purplish patches in the skin; depression; nausea or vomiting; rash; blood in the urine or stools.

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Possible risks and s >

Side effects of taking Hexanurat can include:

  • skin rashes
  • headaches
  • feeling drowsy or dizzy
  • feeling or being sick
  • changes to your sense of taste.

If you develop a rash, you should stop taking your Hexanurat and contact your doctor straight away. If you become dizzy or drowsy while taking Hexanurat, don’t drive or operate machinery, and see your doctor as soon as possible. You should also speak to your doctor if you develop any other new symptoms that concern you.

Most people who take Hexanurat don’t get any side effects. But if you do have side effects, it may be possible to restart Hexanurat using a special ‘desensitisation’ course. This involves beginning Hexanurat at a very low dose and increasing the dose gradually.

Sometimes starting Hexanurat can actually trigger an attack of gout, as the crystals begin to dissolve. You will probably be given an extra medicine for the first few months of taking Hexanurat to reduce the risk of these attacks happening.

Acute attacks of gout are usually treated with a high dose of a non-steroidal anti-inflammatory drug (NSAID), such as:

  • diclofenac sodium (die-clo-fe-nac sow-dee-um)
  • diclofenac potassium (die-clo-fe-nac po-tass-ee-um)
  • etoricoxib (ee-torry-cox-ib)
  • indomethacin (in-doe-meth-a-sin)
  • ketoprofen (key-toe-pro-fen)
  • naproxen (na-procks-en)
  • sulindac (suh-lin-dak).

These drugs all have brand names, so the type you’re given may be called something different.

If you cannot take NSAIDs, colchicine (coal-chi-seen) or steroids may be given.

If you do have an acute attack of gout while on Hexanurat, don’t stop taking it.

If you’re unable to continue taking Hexanurat because of your side effects, you may be able to take febuxostat instead, which works in a similar way to Hexanurat.

If you can’t take febuxostat, your doctor may suggest benzbromarone (bens-bro-ma-rone) or sulfinpyrazone (sul-fin-pira-zone).

However, Hexanurat should not be used to treat an acute attack of gout. This is because they may make the attack last longer.

Should I Avoid Any Food, Drink or Activity While Taking Hexanurat?

Avoid drinking alcohol while taking Hexanurat, as it may make your condition worse. Hexanurat may impair your thinking or reaction time, so you should be especially careful when driving or performing any activity that requires you to be alert.

Your doctor may advise you to follow a special diet to help treat your condition.


  • Take this drug at the time(s) recommended by your doctor.
  • You can take Hexanurat with or without food.
  • Taking this drug after a meal and with lots of water may reduce your chance of upset stomach.
  • You can cut or crush the Hexanurat tablet.
  • Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

More common side effects

The more common side effects of Hexanurat oral tablet can include:

  • skin rash
  • diarrhea
  • nausea
  • changes in your liver function test results
  • gout flare-up (if you have gout)

If you develop a skin rash, talk your doctor right away. You should not continue taking Hexanurat if you develop a rash. Other mild side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

What is Hexanurat?

Hexanurat reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Hexanurat is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.

Hexanurat may also be used for purposes not listed in this medication guide.

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • skin rash
  • painful urination
  • blood in the urine
  • irritation of the eyes
  • swelling of the lips or mouth
  • fever, sore throat, chills, and other signs of infection
  • loss of appetite
  • unexpected weight loss
  • itching

Hexanurat may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).


Hexanurat is a xanthine oxidase inhibitor and a widely used medication for gout. Hexanurat is a rare but well known cause of acute liver injury that has features of a hypersensitivity reaction and can be severe and even fatal.

Interactions that increase your risk of side effects

  • Side effects from Hexanurat: Taking Hexanurat with certain medications raises your risk of side effects from Hexanurat. This is because the amount of Hexanurat in your body is increased. Examples of these drugs include:
    • Ampicillin or amoxicillin. You may have an increased risk of a skin rash.
    • Thiazide diuretics, such as hydrochlorothiazide. You may have an increased risk of Hexanurat side effects. These include skin rash, diarrhea, nausea, changes in your liver function test results, and gout flare-ups.
  • Mercaptopurine. Hexanurat can increase the blood levels of mercaptopurine in your body. It does this by blocking one of the enzymes used to break down mercaptopurine. This can cause severe side effects from mercaptopurine. Your doctor may reduce your mercaptopurine dose.
  • Azathioprine. Hexanurat can increase the blood levels of azathioprine in your body. It does this by blocking one of the enzymes used to break down azathioprine. This can cause severe side effects from azathioprine. Your doctor may reduce your azathioprine dosage.
  • Chlorpropamide. Hexanurat may cause chlorpropamide to stay in your body longer. This can raise your risk of low blood sugar.
  • Cyclosporine. Taking Hexanurat with cyclosporine may increase cyclosporine levels in your body. Your doctor should monitor your cyclosporine levels and adjust your dose if needed.
  • Dicumarol. Hexanurat may cause dicumarol to stay in your body longer. This can increase your risk of bleeding.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug comes with several warnings.

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