Gabanet (Neurontin, Gralise, Horizant, Fanatrex FusePag) is a drug prescribed for the treatment of seizure disorders, nerve damage from shingles and postherptic neuralgia. Off label uses of Gabanet include treatment for:
- Substance abuse withdrawal
- RLS (restless legs syndrome)
- Diabetic neuropathy
- Hot flashes
Warnings for other groups
For pregnant women: The use of Gabanet has not been studied in humans during pregnancy. Research in animals has shown negative effects to the fetus when the mother takes the drug. However, animal studies don’t always predict the way humans would respond.
Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus. Call your doctor if you become pregnant while taking this drug.
If your doctor prescribes Gabanet for you while you’re pregnant, ask about the NAAED Pregnancy Registry. This registry tracks the effects of anti-seizure drugs on pregnancy. Information can be found at aedpregnancyregistry.org.
For women who are breastfeeding: Gabanet may pass into breast milk and cause serious side effects in a breastfeeding child. Tell your doctor if you are breastfeeding. You should decide together if you should stop taking this drug or stop breastfeeding.
For seniors: Kidney function may decrease with age. You may process this drug more slowly than younger people. Your doctor may start you on a lowered dose so that too much of this drug does not build up in your body. Too much of the drug in your body can be dangerous.
For children: Gabanet has not been studied in children for the management of postherpetic neuralgia. It should not be used in people younger than 18 years. This drug should not be used to treat partial seizures in children younger than 3 years.
Coadministration of NEURONTIN (125 to 500 mg; N=48) decreases hydrocodone (10 mg; N=50) Cmax and AUC values in a dose-dependent manner relative to administration of hydrocodone alone; Cmax and AUC values are 3% to 4% lower, respectively, after administration of 125 mg NEURONTIN and 21% to 22% lower, respectively, after administration of 500 mg NEURONTIN. The mechanism for this interaction is unknown. Hydrocodone increases Gabanet AUC values by 14%. The magnitude of interaction at other doses is not known.
When Gabanet is administered with morphine, patients should be observed for signs of central nervous system (CNS) depression, such as somnolence, sedation and respiratory depression .
Q: I started taking Gabanet (100 mg, 1 capsule, 3x daily), as well as amitriptyline (10 mg, 1 tablet, at bedtime) three months ago, for the treatment of fibromyalgia. Since taking these meds, I have gained 11 pounds. I have not changed my eating habits, nor have I cut back on my exercise routine (I still go 6x a week). When I brought this up to my doctor after gaining the first 4 pounds (in the first 1.5 weeks), he upped my dose of Gabanet to 2 capsules 3x daily. Is it one or both of these meds causing me to gain so much weight at such a rapid speed?
A: During studies of the medication Gabanet, up to 2.9 percent of adults taking Gabanet experienced weight gain, compared with just 1.6 percent of adults not taking it. In studies of amitriptyline, patients had both weight gain and weight loss, so it is not possible to attribute this effect to the medication. You should talk with your physician again and let him or her know about the rapid weight gain and make sure it is not fluid retention causing the change.
21. Can Symptoms Occur if Gabanet is Discontinued?
Like other psychotropic drugs, people should ease off Gabanet gradually. There are some known withdrawal symptoms. This mostly comes from people who take high doses of the drug and suddenly stop. People should only abruptly discontinue Gabanet because of a serious side effect.
Rated Gabanet (Neurontin) for Neuropathic Pain Report
I took it for 2 years for sciatica caused by a L5S1 herniation. It worked pretty good for the pain but did not relieve it completely. I stopped it cold turkey which is the number one warning when it comes to this drug. I had heard a few things like that but figured my doctor would have told me about it and stuff. A little while after I quit it cold turkey I went crazy and was extremely manic, delusional, and was hallucinating among a host of other things. I went to the doctors and was diagnosed with schizophrenia, Bipolar 1, PTSD and Psychosis. I'm not saying I for sure have all these things. But I did exhibit the symptoms at the time of diagnosis. Please be very careful with this drug and DON'T QUIT COLD TURKEY. Understand this drug has unapproved and largely unstudied effects that have to do with your BRAIN. It seriously alters your entire NERVOUS SYSTEM. Now I hope the issues I have experienced will not be chronic throughout my life but it's possible they may be. Take care with this one. Best of luck.