• Active Ingredient: Fluticasone
  • 50mcg
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What is Flusonal?

The active ingredient of Flusonal brand is fluticasone. Fluticasone propionate has a molecular weight of 500.6. It is a white to off-white powder and is insoluble in water. Each gram of Fluticasone Propionate Cream, USP 0.05% contains Fluticasone propionate 0.5 mg in a base of propylene glycol, mineral oil, cetostearyl alcohol, Ceteth-20, isopropyl myristate, dibasic sodium phosphate, citric acid, purified water, and methylparaben as preservative.

Used for

Flusonal is used to treat diseases such as: Asthma, Maintenance, Bronchopulmonary Dysplasia, Eosinophilic Esophagitis.

Side Effect

Possible side effects of Flusonal include: stomach pain; fainting; growth reduction in children or adolescents; redness or discharge of the eye, eyelid, or lining of the eye; restlessness; Cough.

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Before using Flusonal, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent nose problems (such as injury, ulcers, surgery), infections (including tuberculosis, herpes eye infection), certain eye problems (glaucoma, cataracts), liver disease.

Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Rarely, using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.

Though it is unlikely, this medication may slow down a child's growth if used for a long time. The effect on final adult height is unknown. See the doctor regularly so your child's height can be checked.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.


Chronic overdosage may result in signs/symptoms of hypercorticism (see PRECAUTIONS). Intranasal administration of 2 mg (10 times the recommended dose) of Flusonal propionate twice daily for 7 days to healthy human volunteers was well tolerated. Single oral doses up to 16 mg have been studied in human volunteers with no acute toxic effects reported. Repeat oral doses up to 80 mg daily for 10 days in volunteers and repeat oral doses up to 10 mg daily for 14 days in patients were well tolerated. Adverse reactions were of mild or moderate severity, and incidences were similar in active and placebo treatment groups. Acute overdosage with this dosage form is unlikely since 1 bottle of FLONASE (Flusonal propionate) Nasal Spray contains approximately 8 mg of Flusonal propionate.

The oral and subcutaneous median lethal doses in mice and rats were >1,000 mg/kg (>20,000 and >41,000 times, respectively, the maximum recommended daily intranasal dose in adults and >10,000 and >20,000 times, respectively, the maximum recommended daily intranasal dose in children on a mg/m 2 basis).


Flusonal Propionate Cream is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.

Generic Name: Flusonal propionate Dosage Form: cream

Medically reviewed by Drugs.com. Last updated on Sep 1, 2018.

Flixot >About Flusonal inhalers
  • Before using a Flusonal inhaler
  • How to use a Flusonal inhaler
  • Getting the most from your treatment
  • Can Flusonal inhalers cause problems?
  • How to store Flusonal inhalers
  • Important information about all medicines
  • When to call the doctor

    • While using this drug, call your doctor or get medical care right away if:
    • your breathing problems get worse
    • you need to use your rescue inhaler more often than usual
    • your rescue inhaler doesn’t work as well to relieve your symptoms
    • you need to use 4 or more inhalations of your rescue inhaler in 24 hours for two or more days in a row
    • you use one whole canister of your rescue inhaler in eight weeks
    • your peak flow meter results decrease (your healthcare provider will tell you the numbers that are right for you)
    • you have asthma and your symptoms don’t improve after using this drug regularly for one week

    Flusonal/salmeterol inhalation powder doesn’t cause drowsiness, but it can cause other side effects.

    Patient Counseling Information

    Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use).

    Local Nasal Effects : Inform patients that treatment with Flusonal propionate nasal spray may lead to adverse reactions, which include epistaxis and nasal ulceration. Candida infection may also occur with treatment with Flusonal propionate nasal spray. In addition, Flusonal propionate nasal spray has been associated with nasal septal perforation and impaired wound healing. Patients who have experienced recent nasal ulcers, nasal surgery, or nasal trauma should not use Flusonal propionate nasal spray until healing has occurred .

    Glaucoma and Cataracts : Inform patients that glaucoma and cataracts are associated with nasal and inhaled corticostero > .

    Hypersensitivity Reactions, including Anaphylaxis : Inform patients that hypersensitivity reactions, including anaphylaxis, angioedema, urticaria, contact dermatitis, and rash, may occur after administration of Flusonal propionate nasal spray. If such reactions occur, patients should discontinue use of Flusonal propionate nasal spray .

    Immunosuppression : Warn patients who are on immunosuppressant doses of corticostero > .

    Reduced Growth Velocity : Advise parents that Flusonal propionate nasal spray may cause a reduction in growth velocity when administered to pediatric patients. Physicians should closely follow the growth of children and adolescents taking corticostero > .

    Use Daily for Best Effect : Inform patients that they should use Flusonal propionate nasal spray on a regular basis. Flusonal propionate nasal spray, like other corticosteroids, does not have an immediate effect on rhinitis symptoms. Maximum benefit may not be reached for several days. Patients should not increase the prescribed dosage but should contact their healthcare providers if symptoms do not improve or if the condition worsens.

    Keep Spray Out of Eyes and Mouth : Inform patients to avoid spraying Flusonal propionate nasal spray in their eyes and mouth.

    Distr. by: West-Ward

    Eatontown, NJ 07724

    Revised January 2019


    HPA Axis Effect : The potential systemic effects of Flusonal propionate nasal spray on the HPA axis were evaluated. Flusonal propionate nasal spray given as 200 mcg once daily or 400 mcg twice daily was compared with placebo or oral prednisone 7.5 or 15 mg given in the morning. Flusonal propionate nasal spray at either dosage for 4 weeks did not affect the adrenal response to 6-hour cosyntropin stimulation, while both dosages of oral prednisone significantly reduced the response to cosyntropin.

    Cardiac Electrophysiology : A study specifically designed to evaluate the effect of Flusonal propionate nasal spray on the QT interval has not been conducted.

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