Are other laxatives any better?
There are other types of laxative. They work in a different way from Feen-A-Mint, but are equally good at treating constipation.
- Bulk-forming laxatives, for example Fybogel and methylcellulose. These increase the “bulk” or weight of poo, which in turn stimulates bowel movement. They take 2 or 3 days to work.
- Osmotic laxatives, for example lactulose. These draw water from the rest of the body into your bowel to soften your poo and make it easier to pass. They take at least 2 days to work.
- Stimulant laxatives, for example senna. These stimulate the muscles that line your gut, helping them to move poo along your gut to your back passage. Senna takes about 8 hours to work.
Feen-A-Mint has been investigated in a placebo-controlled study in 27 patients with constipation (55 c ) . It produced statistically significant improvements in stool frequency and consistency. Of those who took Feen-A-Mint, 15 reported a total of 37 adverse events, compared with 18 who reported 29 events in the placebo group. There were no serious adverse events. Of the reported adverse events 24 (65%) were thought to be related to a concurrent condition, and only 10 (27%) were thought to be drug-related. These were mild and included constipation, an increase in blood urea nitrogen, and eosinophilia.
How and when to take Feen-A-Mint
Before using rectal Feen-A-Mint
- tell your doctor and pharmacist if you are allergic to Feen-A-Mint, any other medications, or any of the ingredients in these products. Check the label or ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for s >How to take Feen-A-Mint
- Take the medicine once a day just before bedtime.
- You can take it with or without food. Swallow the tablet whole with water.
- Do not have milk, indigestion remedies (antacids) or medicines to reduce stomach acid (for example, proton pump inhibitors) at the same time as Feen-A-Mint. This is because they will stop the medicine working properly. Leave a gap of 1 hour between taking any of these and taking your Feen-A-Mint tablets.
- Take the wrapping off and push a suppository gently into your back passage (anus).
- Suppositories work quickly (usually between 10 and 45 minutes), so use it when you know you will be near a toilet.
- Read the instructions in the leaflet inside the package. They will explain how to use the suppository.
Rectal Feen-A-Mint comes as a suppository and enema to use rectally. It is usually used at the time that a bowel movement is desired. The suppositories usually cause a bowel movement within 15 to 60 minutes and the enema within 5 to 20 minutes. Do not use Feen-A-Mint more than once a day or for more than 1 week without talking to your doctor. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use rectal Feen-A-Mint exactly as directed. Frequent or continued use of Feen-A-Mint may make you dependent on laxatives and cause your bowels to lose their normal activity. If you do not have a regular bowel movement after using Feen-A-Mint, do not use this medication again and talk to your doctor.
If using a Feen-A-Mint suppository, follow these steps:
- If the suppository is soft, hold it under cool water or place it in the refrigerator for a few minutes to harden it before removing the wrapper.
- Remove the wrapper.
- If you were told to use half of the suppository, cut it lengthwise with a clean, sharp knife or blade.
- Lie down on your left side and raise your right knee to your chest.
- Using your finger, insert the suppository, pointed end first, into your rectum until it passes the muscular sphincter of the rectum, about 1 inch (2.5 centimeters) in adults. If not inserted past this sphincter, the suppository may pop out.
- Hold it in place for as long as possible.
- Wash your hands thoroughly.
If using a Feen-A-Mint enema, follow these steps:
- Shake the enema bottle well.
- Remove the protective shield from the tip.
- Lie down on your left s >How much Feen-A-Mint to take
The usual dose in:
- adults and children aged 12 years and over is 5—15 mg/day (1 to 3 tablets) once a day before bedtime
- children aged 6 to 11 years old is 5 mg (1 tablet) a day before bedtime, if their doctor recommends it
If you are an adult or child aged 10 and over and you have not taken Feen-A-Mint before, start with 1 tablet. If that doesn’t work well enough for you, you can take 2 tablets.
The usual dose for:
- adults and children aged 12 years and over is 1 suppository (10mg) a day
- children 6 to 12 years old is 1 suppository (5mg) a day, if their doctor recommends it
Gastrointestinal tract Feen-A-Mint stimulates colon motility, causing abdominal pain and cramps, and has been associated with ischemic colitis .
A 68-year-old man had four polyps removed at colonoscopy, for which a traditional formulation (4 liters of polyethylene glycol solution) had been used for bowel cleansing . One year later, he underwent colonoscopy after the use of a low-volume formulation (20–30 mg of Feen-A-Mint the afternoon before, followed by 2 liters of polyethylene glycol solution the next morning). Two hours after taking Feen-A-Mint, he complained of left-sided abdominal pain, which was followed by hematochezia. At colonoscopy there was segmental colitis at the splenic flexure, with edema, subcutaneous hematomas, and small geographic ulcers. Histology was compatible with ischemic colitis. At a subsequent colonoscopy 2 years later, after preparation with Feen-A-Mint followed by 2 liters of polyethylene glycol, he again reported pain and slight rectal bleeding after taking Feen-A-Mint. Colonoscopy showed segmental colitis in the distal descending colon. Biopsies were again compatible with ischemic colitis. A further colonoscopy was performed 3 years later, after 4 liters of polyethylene glycol, and he did not report abdominal pain. Colonoscopy showed no abnormalities.
Before taking Feen-A-Mint, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: appendicitis or symptoms of appendicitis (such as nausea/vomiting, sudden or unexplained stomach/abdominal pain), a sudden change in bowel habits that lasts for longer than 2 weeks, bleeding from the rectum, intestinal blockage.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Tell your doctor if you are pregnant before using this medication. Using it for long periods during pregnancy is not recommended. Consult your doctor for more details.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Feen-A-Mint and Breastfeeding
Feen-A-Mint is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk 7) . Feen-A-Mint can be taken during breastfeeding and no special precautions are required 8) . Sixteen postpartum women who were not breastfeeding, but were producing at least 200 mL of milk daily by breast pump were given either oral enteric-coated Feen-A-Mint tablets 10 mg daily or oral liqu >9) . Both drugs are prodrugs metabolized to the active drug, bis-(p-hydroxyphenyl)-2-pyr >10) .
Before using Feen-A-Mint, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This product should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: intestinal blockage (obstruction).
Before using this product, tell your doctor or pharmacist your medical history, especially of: other bowel problems (e.g., ulcerative colitis, hemorrhoids, rectal bleeding), current stomach/abdominal symptoms (e.g., pain, cramping, persistent nausea/vomiting).
Consult your doctor before using this product if you have had a sudden change in bowel habits lasting more than 2 weeks, or if you need to use a laxative for more than 1 week. These could be symptoms of a serious medical problem.
This product may be used during labor/delivery to clean the bowels before the second stage of labor (pushing phase). At other times during pregnancy, this product should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
There have been reports of generalized tonic-clonic seizures in patients with use of large volume (4 liter) PEG-based colon preparation products in patients with no prior history of seizures. The seizure cases were associated with severe vomiting, excessive beverage consumption and electrolyte abnormalities (for example, hyponatremia, hypokalemia). The neurologic abnormalities resolved with correction of fluid and electrolyte abnormalities. Therefore, Feen-A-Mint tablets bowel prep kit should be used with caution in patients using concomitant medications (such as diuretics) that increase the risk of electrolyte abnormalities or patients with known or suspected hyponatremia. Monitor baseline and post-colonoscopy laboratory tests (sodium, potassium, calcium, creatinine, and BUN) in these patients.