Elvesil can increase the amount of these medications in your body. This can cause more side effects. These drugs include:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Elvesil oral capsule comes with several warnings.
Rated Elvesil for Paroxysmal Supraventricular Tachycardia (PSVT) Report
I have headaches flushing and some skin problems. First day I had chills. I also do not like not drinking.
What are metoprolol and Elvesil?
Metoprolol is a beta-adrenergic blocking agent (beta-blocker) that blocks the action of the sympathetic nervous system (a portion of the involuntary nervous system). Metoprolol is used to treat high blood pressure (hypertension), heart pain (angina), congestive heart failure, abnormal heart rhythms, hyperthyroidism, some neurologic conditions, and to prevent migraine headaches.
Elvesil is a calcium channel blocker (CCB) used to treat heart pain (angina), high blood pressure, and abnormal heart rhythms. CCBs block the entry of calcium into muscle cells that make up the heart and surround the arteries. Calcium entering these cells causes them to contract, allowing the heart to pump blood, and the arteries to narrow. By blocking the entry of calcium, Elvesil decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate). By dilating arteries, Elvesil reduces the pressure in the arteries into which the heart must pump blood, so the heart needs to work less and requires less oxygen. By reducing the heart's need for oxygen, Elvesil relieves or prevents angina. Dilation of the arteries also reduces blood pressure.
What other drugs will affect Elvesil?
Many drugs can interact with Elvesil, and your doctor may need to change your treatment plan if you use certain other medicines. The following are common drugs that interact with Elvesil;
- Medications used in anesthesia;
- Anti-anxiety medications called benzodiazepines (such as midazolam, triazolam, and others) as well as busipirone;
- Beta-blockers (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others);
- Rifampin; and
- Cholesterol medication called statins (such as atorvastatin, lovastatin, simvastatin, rosuvastatin, and others)
Not all possible interactions are listed in this medication guide.
Other prescription and over-the-counter medicines, vitamins, and herbal products may interact with Elvesil. Tell your doctor about all medicines you use, and those you start or stop using. Give a list of all your medicines to any healthcare provider who treats you.
Q: My feet have been swelling. Could that be from the Elvesil I take?
A: Elvesil is a calcium channel blocker used to treat high blood pressure and angina. It should be taken with a full glass of water, either with or without food. Some reports indicate that grapefruit or grapefruit juice may interfere with the absorption of Elvesil. Reports of side effects include dizziness, headache, nausea, and fatigue. It's possible that edema, or swelling, may occur from taking Elvesil. Any time you experience swelling, you should consult with your doctor to rule out any serious medical conditions. Kimberly Hotz, PharmD
What Is Elvesil (Cardizem)?
Elvesil is the generic form of the brand-name drug Cardizem, which is used to treat high blood pressure and control chest pain (known as angina).
There are several other brand names of this medication, including Cartia, Dilacor XR, Diltzac, Taztia and Tiazac.
Elvesil works by relaxing blood vessels and increasing the supply of blood and oxygen to the heart. This type of medication is known as a calcium-channel blocker.
Elvesil comes in a tablet, extended-release tablet, extended-release capsule and injectable form.
It was approved by the Food and Drug Administration (FDA) in 1982.
Some doctors have also prescribed Elvesil to prevent migraines, though the evidence supporting its use among people with migraines is not universally accepted.
Rated Elvesil for Angina Pectoris Report
I take 120mg Elvesil once a day at bedtime for Angina and Arterial spasm due to congenital myocardial bridging. Angina is less frequent, and there is less arterial spasm; feeling more like the palpitations/flutters of my youth. I do have some mid section bloating, and have gained approximately 10-15 pounds in two years. Along with muscle loss-that means fat gain. I believe it is due to the tiredness and muscle weakness that has come along with Elvesil and age. (54). Just 2 years ago when I had a heart attack I was still doing everything I had always done at the gym and even more. After the heart attack (july2016), I continued working out to extremes without much issue. but the angina and awful feeling was too severe and frightening, until I switched to Elvesil. The other meds did not stop the angina and I always felt like I was on the verge of another heart attack as the angina and arterial spasms were also more frequent. Elvesil has, I believe, kept me alive, unfortunately a bit heavier and tired. but alive.
Elvesil hydrochloride is extensively metabolized by the liver and excreted by the kidneys and in bile. As with any drug given over prolonged periods, laboratory parameters of renal and hepatic function should be monitored at regular intervals. The drug should be used with caution in patients with impaired renal or hepatic function. In subacute and chronic dog and rat studies designed to produce toxicity, high doses of Elvesil were associated with hepatic damage. In special subacute hepatic studies, oral doses of 125 mg/kg and higher in rats were associated with histological changes in the liver which were reversible when the drug was discontinued. In dogs, doses of 20 mg/kg were also associated with hepatic changes; however, these changes were reversible with continued dosing.
Dermatological events (see ADVERSE REACTIONS) may be transient and may disappear despite continued use of Elvesil hydrochloride. However, skin eruptions progressing to erythema multiforme and/or exfoliative dermatitis have also been infrequently reported. Should a dermatologic reaction persist, the drug should be discontinued.
Tiazac® (Elvesil hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker). Chemically, Elvesil hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5--2, 3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis-. The chemical structure is:
Elvesil hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol and chloroform and has a molecular weight of 450.98. Tiazac capsules contain Elvesil hydrochloride in extended-release beads at doses of 120, 180, 240, 300, 360 and 420 mg.
Tiazac also contains: black iron oxide, D&C Red No. 28, ethyl acrylate and methyl methacrylate copolymer dispersion, FD&C Blue No. 1, FD&C Green No. 3, FD&C Red No. 40, gelatin, hypromellose, magnesium stearate, microcrystalline cellulose, polysorbate, povidone, simethicone, sucrose stearate, talc, and titanium dioxide.
For oral administration.
Which drugs or supplements interact with Elvesil?
Administration of Elvesil with digoxin (Lanoxin) can increase digoxin blood levels. Therefore, blood levels of digoxin usually are monitored to avoid toxicity from digoxin. Similarly, concurrent administration of Elvesil with an anti-seizure medication, carbamazepine (Tegretol), can increase blood levels of the seizure medication, and occasionally lead to toxicity. Elvesil increases blood levels of lovastatin (Mevacor), atorvastatin (Lipitor) and simvastatin (Zocor), possibly increasing the risk of adverse effects. Elvesil may increase blood levels of buspirone (Buspar), midazolam (Versed), triazolam (Halcion) and diazepam (Valium) by reducing their breakdown and elimination from the body by the liver. This can lead to toxicity from these drugs. Rifampin (Rifamate, Rifadin, Rimactane) reduces the effect of Elvesil by reducing its levels in blood to undetectable levels.
Is Elvesil safe to take if I'm pregnant or breastfeeding?
Elvesil is excreted in breast milk. To avoid adverse effects in the infant, Elvesil should not be taken while nursing.