ВїPara cuГЎles condiciones o enfermedades se prescribe este medicamento?
El Dilcontin se usa para tratar la presiГіn arterial alta y controlarangina (dolor en el pecho). El Dilcontin pertenece a una clase de medicamentos llamados bloqueadores de los canales de calcio. ActГєa relajando los vasos sanguГneos, de modo que el corazГіn no tenga que bombear con tanta fuerza. TambiГ©n aumenta el flujo sanguГneo y la oxigenaciГіn del corazГіn.
La hipertensiГіn arterial es una condiciГіn comГєn y cuando no se trata, puede causar daГ±os en el cerebro, el corazГіn, los vasos sanguГneos, los riГ±ones y otras partes del cuerpo. El daГ±o a estos Гіrganos puede causar enfermedades del corazГіn, un infarto, insuficiencia cardГaca, apoplejГa, insuficiencia renal, pГ©rdida de la visiГіn y otros problemas. AdemГЎs de tomar medicamentos, hacer cambios de estilo de vida tambiГ©n le ayudarГЎ a controlar su presiГіn arterial. Estos cambios incluyen comer una dieta que sea baja en grasa y sal, mantener un peso saludable, hacer ejercicio al menos 30 minutos casi todos los dГas, no fumar y consumir alcohol con moderaciГіn.
You should not use Dilcontin if you have very low blood pressure, a serious heart condition such as "sick sinus syndrome" or "second- or third-degree AV block" (unless you have a pacemaker), or if you have recently had a heart attack and you have a build-up of fluid in your lungs.
Before taking Dilcontin, tell your doctor if you have kidney disease, liver disease, or congestive heart failure.
Dilcontin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Do not stop taking this medication without first talking to your doctor. If you stop taking Dilcontin suddenly, your condition may become worse.
Dilcontin may be only part of a complete program of treatment that also includes diet, exercise, and other medications. Follow your diet, medication, and exercise routines very closely.
If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. However, if you have symptoms of low blood pressure (dizziness, fainting, weakness, or blurred vision), call your doctor and stop taking Dilcontin.
Dilcontin is used for the same spectrum of CV disease as verapamil: hypertension, angina pectoris, prevention of AV nodal reentry, tachycardia, and rate control in acute and chronic AF. The side-effect profile is similar, except that constipation is much less common.
How to use Dilcontin Hcl
Take this medication by mouth before meals and at bedtime as directed by your doctor, usually 3 to 4 times a day. Swallow the tablets whole. Do not split, crush, or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Follow your doctor's directions on how to take this medication.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may gradually increase your dose. Follow your doctor's instructions carefully.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. This medication must be taken regularly to prevent angina. It should not be used to treat angina when it occurs. Use other medications (such as sublingual nitroglycerin) to relieve an angina attack as directed by your doctor. Consult your doctor or pharmacist for details.
Tell your doctor if your condition worsens (for example, your chest pain worsens or is more frequent).
What is Dilcontin, and how does it work (mechanism of action)?
Dilcontin is a drug that is used for treating heart pain (angina), high blood pressure, and abnormal heart rhythms.
CCBs block the entry of calcium into muscle cells that make up the heart and that surround the arteries. It is the entry of calcium into these cells that causes the cells to contract, allowing the heart to pump blood, and the arteries to narrow. By blocking the entry of calcium, Dilcontin decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate). In order to pump blood, the heart needs oxygen. The harder the heart works, the more oxygen it requires. Angina occurs when the supply of oxygen to the heart is inadequate for the amount of work the heart must do.
By dilating arteries, Dilcontin reduces the pressure in the arteries into which the heart must pump blood, and, as a result, the heart needs to work less and requires less oxygen. By reducing the heart's need for oxygen, Dilcontin relieves or prevents angina. Dilation of the arteries also reduces blood pressure.
The FDA approved Dilcontin in 1982.
Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with Dilcontin. Monitor heart rate in patients receiving concomitant Dilcontin and clonidine.
GENERIC NAME(S): Dilcontin Hcl
OTHER NAME(S): Diltzac ER Capsule, Extended Release 24 Hr (Capsule, ER 24 Hr)
Dilcontin is used to treat high blood pressure (hypertension) and prevent chest pain (angina). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. When used regularly, Dilcontin can decrease the number and severity of episodes of chest pain from angina. It may help increase your ability to exercise.
Dilcontin is called a calcium channel blocker. It works by relaxing blood vessels in the body and heart so blood can flow more easily. Dilcontin also lowers your heart rate. These effects help the heart work less hard and lower blood pressure.
Serious adverse reactions have been rare in studies with Tiazac, as well as with other Dilcontin formulations. It should be recognized that patients with impaired ventricular function and cardiac conduction abnormalities have usually been excluded from these studies. A total of 256 hypertensives were treated for between 4 and 8 weeks; a total of 207 patients with chronic stable angina were treated for 3 weeks with doses of Tiazac ranging from 120 to 540 mg once daily. Two patients experienced first-degree AV block at the 540 mg dose. The following table presents the most common adverse reactions, whether or not drug-related, reported in placebo-controlled trials in patients receiving Tiazac up to 360 mg and up to 540 mg with rates in placebo patients shown for comparison.
MOST COMMON ADVERSE EVENTS IN DOUBLE-BLIND PLACEBO-CONTROLLED HYPERTENSION TRIALS*
MOST COMMON ADVERSE EVENTS IN DOUBLE-BLIND PLACEBO-CONTROLLED ANGINA TRIALS*
In addition, the following events have been reported infrequently (less than 2%) in clinical trials with other Dilcontin products:
Cardiovascular: Angina, arrhythmia, AV block (second- or third-degree), bundle branch block, congestive heart failure, ECG abnormalities, hypotension, palpitations, syncope, tachycardia, ventricular extrasystoles.
Nervous System: Abnormal dreams, amnesia, depression, gait abnormality, hallucinations, insomnia, nervousness, paresthesia, personality change, somnolence, tinnitus, tremor.
Gastrointestinal: Anorexia, constipation, diarrhea, dry mouth, dysgeusia, mild elevations of SGOT, SGPT, LDH, and alkaline phosphatase (see WARNINGS, Acute Hepatic Injury), nausea, thirst, vomiting, weight increase.
Other: Albuminuria, allergic reaction, amblyopia, asthenia, CPK increase, crystalluria, dyspnea, edema, epistaxis, eye irritation, headache, hyperglycemia, hyperuricemia, impotence, muscle cramps, nasal congestion, neck rigidity, nocturia, osteoarticular pain, pain, polyuria, rhinitis, sexual difficulties, gynecomastia.
In addition, the following postmarketing events have been reported infrequently in patients receiving Dilcontin hydrochloride: acute generalized exanthematous pustulosis, alopecia, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, extrapyramidal symptoms, gingival hyperplasia, hemolytic anemia, increased bleeding time, photosensitivity (including lichenoid keratosis and hyperpigmentation at sun-exposed skin areas), leukopenia, purpura, retinopathy, and thrombocytopenia. In addition, events such as myocardial infarction have been observed which are not readily distinguishable from the natural history of the disease in these patients. A number of well-documented cases of generalized rash, characterized as leukocytoclastic vasculitis, have been reported. However, a definitive cause and effect relationship between these events and Dilcontin hydrochloride therapy is yet to be established.
Q: I take Cardizem for high blood pressure, and lately I've had acne on my face. Could that be caused by the medication?
A: A variety of skin rashes and pustules have been reported in patients taking Cardizem (Dilcontin). Most aren't serious, but they should be evaluated by your health care provider. If you experience fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, contact your doctor at once. This can be a sign of a serious side effect. For more information, go to //www.everydayhealth.com/drugs/Dilcontin. Sarah Lewis, PharmD
Forms and strengths
- Form: Oral immediate-release tablet
- Strengths: 30 mg, 60 mg, 90 mg, 120 mg
Brand: Cardizem CD
- Form: Oral immediate-release capsule
- Strengths: 120 mg, 180 mg, 240 mg, 300 mg, 360 mg
Brand: Cardizem LA
- Form: Oral extended-release capsule
- Strengths: 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg
- Form: Oral extended-release capsule
- Strengths: 60 mg, 90 mg, 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg
WHAT IS Dilcontin?
Dilcontin is used to treat several medical conditions, including hypertension (high blood pressure), angina (chest pain), and even to slow unusually fast heartbeats.
Dilcontin is in a class of drugs called calcium channel blockers. It works by relaxing (widening) your blood vessels (veins and arteries), which in turn makes it easier for your heart to pump and reduces the workload on it.
Some of the brand names that Dilcontin is marketed under include Cardizem®, Cartia XT®, Tiazac®, and Tiamate®.
Warnings for people with certain health conditions
For people who have had a recent heart attack: If you’ve had a recent heart attack and have fluid buildup in your lungs, you shouldn’t take this drug. Dilcontin could worsen your condition by slowing down your heart.
For people with liver disease: Dilcontin may cause more harm to your liver. Your doctor may monitor your liver function while you’re on this drug.
For people with certain heart problems: You shouldn’t use Dilcontin if you have sick sinus syndrome or atrioventricular (AV) block unless you have a pacemaker. This drug can rarely cause a very slow heart rate. Your risk for this may be higher if you take other heart medications called beta-blockers or digoxin. If you have heart failure, your symptoms may get worse if you use this drug, especially if also use beta-blockers. If you have heart failure, tell your doctor.
Metoprolol vs. Dilcontin: What's the difference?
- Metoprolol and Dilcontin are used to treat high blood pressure (hypertension), heart pain (angina), and abnormal heart rhythms.
- Metoprolol is also used to treat congestive heart failure, hyperthyroidism, and some neurologic conditions, and to prevent migraineheadaches.
- Brand names for metoprolol include Lopressor and Toprol XL.
- Brand names for Dilcontin include Cardizem, Cardizem CD, Cardizem LA, Tiazac, Cartia XT, Diltzac, and Dilt-CD.
- Metoprolol and Dilcontin belong to different drug classes. Metoprolol is a beta-blocker (beta-adrenergic blocking agent) and Dilcontin is a calcium channel blocker (CCB).
- Side effects of metoprolol and Dilcontin that are similar include constipation, nausea, and low blood pressure (hypotension).
- Side effects of metoprolol that are different from Dilcontin include abdominal cramps, diarrhea, fatigue, insomnia, indigestion, depression, dreaming, memory loss, fever, impotence, lightheadedness, decreased exercise tolerance, increased triglycerides, bronchospasm, cold extremities, sore throat, shortness of breath, or wheezing.
- Side effects of Dilcontin that are different from metoprolol include headache, rash, swelling of the legs and feet with fluid (edema), drowsiness, dizziness, liver dysfunction, overgrowth of the gums, and mildly abnormal liver tests.
Administration of Dilcontin hydrochloride with digoxin in 24 healthy male subjects increased plasma digoxin concentrations approximately 20%. Another investigator found no increase in digoxin levels in 12 patients with coronary artery disease. Since there have been conflicting results regarding the effect of digoxin levels, it is recommended that digoxin levels be monitored when initiating, adjusting, and discontinuing Dilcontin hydrochloride therapy to avoid possible over- or under-digitalization (see WARNINGS).