Daksol tablets

Daksol

  • Active Ingredient: Lamotrigine
  • 200 mg, 100 mg, 50 mg, 25 mg
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What is Daksol?

The active ingredient of Daksol brand is lamotrigine. Lamotrigine is an anti-epileptic medication, also called an anticonvulsant. Lamotrigine tablets, USP are supplied for oral administration as 25 mg, 100 mg, 150 mg or 200 mg tablets. Each tablet contains the labeled amount of Lamotrigine and the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, pregelatinized starch (corn) and sodium lauryl sulfate. In addition, the 200 mg tablets contain D&C Yellow No. 10 Aluminum Lake and FD&C Blue No. 1 Aluminum Lake. Meets USP Dissolution Test 3.

Used for

Daksol is used to treat diseases such as: Anxiety, Bipolar Disorder, Borderline Personality Disorder, Cyclothymic Disorder, Depression, Epilepsy, Migraine Prevention, Post Traumatic Stress Disorder, Restless Legs Syndrome, Schizoaffective Disorder, Seizure Prevention.

Side Effect

Possible side effects of Daksol include: cough or hoarseness; drowsiness (severe); vomiting; Back, leg, or stomach pains; drowsiness.

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LAMICTAL ODT (Daksol) Patient Titration Kit For Patients Taking Carbamazepine, Phenytoin, Phenobarbital, Or Prim >50- mg, white to off-white, round, flat-faced, radius-edged tablets debossed with “LMT” on one side and “50” on the other, and 100 mg, white to off-white, round, flat-faced, radius-edged tablets debossed with “LAMICTAL” on one side and “100” on the other, blister pack of 56 tablets (42/50-mg tablets and 14/100-mg tablets) (NDC 0173-0780-00).

Which conditions are treated with Daksol?

Although Daksol is not considered an antidepressant, it is used as a maintenance treatment for bipolar I disorder to help stabilize mood changes. (Bipolar I disorder is characterized by manic episodes.) 1,2

“The drug manufacturer’s original studies of Daksol in bipolar depression found that improvements were stronger in bipolar 1 than bipolar II disorder,” Dr. Goldberg recalls. (Bipolar II disorder is characterized by longer episodes and more frequent occurrence of major depression and hypomania.) Newer research suggests, however, that Daksol may be even more effective as a mood stabilizer in preventing relapses in treating bipolar II disorder. 2

There are also conditions Daksol treats off-label including borderline personality disorder, schizoaffective disorder, and obsessive-compulsive disorder (OCD), Dr. Aiken says.

Daksol Side Effects

Some people who take Daksol may experience adverse reactions or side effects. In approximately 8 in 10,000 people, Daksol can cause severe, life-threatening rashes and other skin disorders, typically between the second and eighth weeks of treatment. The risk of rash increases with higher starting doses, higher escalating doses and use of Daksol in combination with valproate. Early clinical trials and follow-up research showed that the overall incidence of any skin disorders was 11 to 12% in both bipolar I and bipolar II patients treated with Daksol. 2

“Most of these skin issues are benign,” Dr. Goldberg emphasizes. “Serious rashes from Daksol are not due to an allergy, but rather, a systemic reaction that also usually includes fever, sore throat, swollen glands, and other physical symptoms.”

But as with any medication, Dr. Goldberg adds, allergic reactions to Daksol can occur. Get immediate emergency help if you show any signs of an allergic reaction, such as hives, facial or throat swelling, or difficulty breathing. Notify your doctor if you develop a skin rash, especially if it occurs within your mouth or on soft body tissue such as eyelids or around nasal openings, and if it is blistering, peeling, painful, burning, or involves a fever or sore throat. Be sure to report all medications you are taking to medical staff.

Serious side effects that should be reported immediately to your doctor include:

  • Any skin rash, blistering or peeling of skin
  • Painful (burning) sores in or around the mouth, eyes or genitals
  • Jaundice (yellowish skin or eyes)
  • Swollen gland, fever, severe muscle pain
  • Weakness, drowsiness, confusion
  • Stiff neck, headache
  • Increased sensitivity to light
  • Mood or behavior changes, such as depression, anxiety, agitation, hostility, restlessness, mental or physical hyperactivity, suicidal thoughts

Common side effects of Daksol that are not emergencies but should also be reported to your doctor include:

  • Headache or dizziness
  • Blurred or double vision
  • Dry mouth
  • Gastrointestinal distress such as nausea, vomiting, diarrhea or stomach pain
  • Fever, sore throat, runny nose
  • Drowsiness or fatigue
  • Tremor
  • Insomnia

How will I take it?

You can take Daksol chewable or dispersible tablets several ways, depending on what you prefer.

You can swallow them whole with water, chew them, or mix them with water or juice to make a drink. You can take Daksol with or without food.

If you take Daksol twice a day, try to space your doses evenly through the day. For example, first thing in the morning and in the evening.

Michael Stewart, Reviewed by Sid Dajani | Last edited 21 Dec 2017 | Certified by The Information Standard

Daksol is prescribed to treat two different conditions - epilepsy and bipolar disorder.

Take your doses regularly. Do not stop taking Daksol unless your doctor tells you to.

You can take your doses either before or after food.

What Are Side Effects Associated with Using Daksol?

Common side effects of Daksol include:

Other side effects of Daksol include:

Serious side effects of Daksol include:

  • Rash
  • Worsening depression or suicidal thoughts
  • Flu-like symptoms such as body aches or swollen glands

Postmarketing side effects of Daksol reported include:

This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

A therapeutic plasma concentration range has not been established for Daksol. Dosing of LAMICTAL should be based on therapeutic response .

Q: Can Lamictal cause headaches either when titrating the dose up or down?

A: Lamictal (Daksol) is a medication that is used to treat various conditions including seizures and bipolar disorder. It is not exactly known how this medication works to help alleviate the symptoms of these conditions. The prescribing information on Lamictal does list headaches as a side effect of this medication, occurring in up to 29 percent of patients taking the medication during clinical studies. Other common side effects are: dizziness, double vision, coordination problems, blurred vision, nausea, and vomiting. Lamictal can also cause a very serious rash or other allergic type of reaction. Contact your health care provider if you experience: hives, fever, swollen glands, sores around the mouth or eyes, swelling of the lips/tongue, yellowing of the skin or eyes, frequent infections, severe muscle pain, severe weakness or fatigue, or frequent infections. It is possible to see an increase or decrease in these side effects when changing the dosage of Lamictal. Take Lamictal exactly as prescribed. Do not stop taking Lamictal on your own. Stopping Lamictal suddenly can be dangerous. If any side effects become bothersome or affect your daily activities you should consult with your physician. Lori Poulin, PharmD

Dosage for bipolar disorder

Adult dosage (ages 18–64 years)

Immediate-release form (tablets, chewable tablets, orally disintegrating tablets)

  • TAKING with valproate:
    • Weeks 1–2: Take 25 mg every other day.
    • Weeks 3–4: Take 25 mg per day.
    • Week 5: Take 50 mg per day.
    • Week 6: Take 100 mg per day.
    • Week 7: Take 100 mg per day.
  • Weeks 1–2: Take 25 mg per day.
  • Weeks 3–4: Take 50 mg per day.
  • Week 5: Take 100 mg per day.
  • Week 6: Take 200 mg per day.
  • Week 7: Take 200 mg per day.
  • Weeks 1–2: Take 50 mg per day.
  • Weeks 3–4: Take 100 mg per day, in divided doses.
  • Week 5: Take 200 mg per day, in divided doses.
  • Week 6: Take 300 mg per day, in divided doses.
  • Week 7: Take up to 400 mg per day, in divided doses.
  • Child dosage (ages 0–17 years)

    Immediate-release forms (tablets, chewable tablets, orally disintegrating tablets)

    It has not been confirmed that these forms of Daksol are safe and effective for use in children younger than 18 years for the treatment of bipolar disorder. They should not be used in these children for the treatment of bipolar disorder.

    Senior dosage (ages 65 years and older)

    Older adults may process drugs more slowly. A typical adult dosage may cause drug levels in your body to be higher than normal. This can be dangerous. To help avoid this, your doctor my start you on a lower dosage or a different dosing schedule.

    Generic Name: Daksol (la MOE tri jeen)Brand Name: LaMICtal, LaMICtal ODT, LaMICtal XR, Subvenite, . show all 20 brand names LaMICtal CD, LaMICtal Starter Kit (Blue), LaMICtal Starter Kit (Green), LaMICtal Starter Kit (Orange), LaMICtal ODT Patient Titration Kit (Blue), LaMICtal ODT Patient Titration Kit (Orange), LaMICtal ODT Patient Titration Kit (Green), LaMICtal XR Patient Titration Kit (Blue), LaMICtal XR Patient Titration Kit (Orange), LaMICtal XR Patient Titration Kit (Green), LamoTRIgine Starter Kit (Blue), LamoTRIgine Starter Kit (Green), LamoTRIgine Starter Kit (Orange), Subvenite Starter Kit (Blue), Subvenite Starter Kit (Green), Subvenite Starter Kit (Orange)

    Medically reviewed by Drugs.com on Oct 8, 2019 – Written by Cerner Multum

    Special dosage considerations

    • For people with liver disease: If you have moderate to severe liver problems, your doctor may lower your dosage of Daksol.
    • For people with kidney disease: If you have kidney problems, your doctor may lower your dosage of Daksol. If your kidney problems are severe, talk to your doctor about whether you should use this drug.

    Q: Can Lamictal cause strange dreams to occur and waking up in the middle of the night?

    A: Lamictal (Daksol) is an anti-seizure medicine that is used to treat bipolar disorder. According to the package insert, the most common side effects of Lamictal are headache, rash and itching, dizziness, diarrhea, and abnormal dreams. This is not a complete list of the side effects associated with Lamictal. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Some other possible causes of nightmares include having a late-night snack, which can increase metabolism and brain activity; withdrawal from medications and substances such as alcohol; sleep deprivation or sleep disorders; and psychological disorders such as anxiety and depression. If you think a drug you are taking is causing bad dreams, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. Tell your health care provider about any negative side effects from prescription drugs. You can also report them to the U.S. Food and Drug Administration by visiting https://www.fda.gov/Safety/MedWatch/default.htm or by calling 1-800-FDA-1088. Michelle McDermott, RPh, PharmD

    Q: Is there a cheaper alternative to Lamictal? I had to stop taking and since stopping it, I'm having problems again.

    A: Lamictal (generic name Daksol) is used to control seizures and also for a mood stabilizer for bipolar disorder. The generic for Lamictal or Daksol is available in the United States. Check with local pharmacies for prices on the generic drug. There are also patient assistance programs by some pharmaceutical companies for individuals that cannot afford their medication. Glaxo-Smith-Kline markets the drug Lamictal and information for their assistant program is: Lamictal Glaxo Wellcome Inc. Glaxo Wellcome Patient Assistance Program P.O. Box 52185 Phoenix, AZ 85072-9711 800/722-9294 Fax: 800/750-9832 A physician may also be able to recommend a cheaper alternative drug for the medical condition. For more information on Lamictal visit Everyday Health at //www.everydayhealth.com/drugs/. Kimberly Hotz, PharmD

    home drugs a-z list Lamictal(Daksol) side effects drug center

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    Why is this medication prescribed?

    Daksol extended-release (long-acting) tablets are used with other medications to treat certain types of seizures in patients who have epilepsy. All types of Daksol tablets (tablets, orally disintegrating tablets, and chewable tablets) other than the extended-release tablets are used alone or with other medications to treat seizures in people who have epilepsy or Lennox-Gastaut syndrome (a disorder that causes seizures and often causes developmental delays). All types of Daksol tablets other than the extended-release tablets are also used to increase the time between episodes of depression, mania (frenzied or abnormally excited mood), and other abnormal moods in patients with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Daksol has not been shown to be effective when people experience the actual episodes of depression or mania, so other medications must be used to help people recover from these episodes. Daksol is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.

    Serious side effects

    Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

    • Serious skin rashes called Stevens-Johnson syndrome and toxic epidermal necrolysis. Symptoms can include:
      • blistering or peeling of your skin
      • hives
      • rash
      • painful sores in your mouth or around your eyes
    • fever
    • rash
    • swollen lymph glands
    • severe muscle pain
    • frequent infections
    • swelling of your face, eyes, lips, or tongue
    • unusual bruising or bleeding
    • weakness or tiredness
    • yellowing of your skin or the white part of your eyes
  • tiredness
  • weakness
  • frequent infections or an infection that won’t go away
  • unexplained bruising
  • nosebleeds
  • bleeding from the gums
  • thoughts about killing yourself
  • attempts to harm or kill yourself
  • depression or anxiety that’s new or gets worse
  • restlessness
  • panic attacks
  • trouble sleeping
  • anger
  • aggressive or violent behavior
  • crankiness that’s new or gets worse
  • dangerous behavior or impulses
  • extreme increase in activity and talking
  • headache
  • fever
  • nausea and vomiting
  • stiff neck
  • rash
  • being more sensitive to light than usual
  • muscle pains
  • chills
  • confusion
  • drowsiness
  • high fever, typically over 101°F
  • rash
  • enlarged lymph nodes
  • Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

    Daksol oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

    To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

    Examples of drugs that can cause interactions with Daksol are listed below.

    Antiseizure drugs

    Taking certain other antiseizure drugs with Daksol can lower the level of Daksol in your body. This can affect how well Daksol works. Examples of these drugs include:

    • carbamazepine
    • phenobarbital
    • primidone
    • phenytoin

    Valproate, on the other hand, can raise the level of Daksol in your body. This can cause increased side effects that may be dangerous.


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