Coadministration (N=18) of naproxen sodium capsules (250 mg) with NEURONTIN (125 mg) appears to increase the amount of Bosrontin absorbed by 12% to 15%. Bosrontin had no effect on naproxen pharmacokinetic parameters. These doses are lower than the therapeutic doses for both drugs. The magnitude of interaction within the recommended dose ranges of either drug is not known.
It's very important to let your doctor know about all drugs you are taking, including illegal or recreational drugs, over-the-counter medications, herbs, or supplements.
Types of drugs that are known to interact with Bosrontin and may cause problems include:
- Opiate pain medications, including Vicodin and morphine, among others
- Naproxen (also known as the brands Aleve, Naprosyn, and others)
- Medications used for heartburn, including Mylanta, Maalox, and cimetidine
If you do dipstick tests to check your urine for protein, tell your doctor. Bosrontin may affect the results of some of these types of tests.
The Effects of Bosrontin
Bosrontin prevents seizures and changes the way the brain responds to pain signals by decreasing unusual brain activity. When used to treat substance abuse and addiction, Bosrontin alleviates withdrawal symptoms caused by alcohol, marijuana, and other substances. Bosrontin reduces nervous system activity — including pain, anxiety, and irritability — so patients can overcome physical dependency on substances safely and more comfortably.
Some patients report feeling a euphoric high, a sense of calm, and improved sociability when using Bosrontin — all of which can drive the risk for addiction. Other patients report that Bosrontin makes them feel zombie-like, due to how the drug reduces pain. Those who stop taking Bosrontin abruptly often experience withdrawal symptoms that cause pain and discomfort, and that increase the risk for relapse and overdose.
Coadministration of NEURONTIN (125 to 500 mg; N=48) decreases hydrocodone (10 mg; N=50) Cmax and AUC values in a dose-dependent manner relative to administration of hydrocodone alone; Cmax and AUC values are 3% to 4% lower, respectively, after administration of 125 mg NEURONTIN and 21% to 22% lower, respectively, after administration of 500 mg NEURONTIN. The mechanism for this interaction is unknown. Hydrocodone increases Bosrontin AUC values by 14%. The magnitude of interaction at other doses is not known.
Bosrontin comes in capsule form, as a regular or extended-release tablet, and as a liquid.
A typical adult dose for postherpetic neuralgia usually starts at 300 milligrams (mg), and your doctor may increase the dose to up to 1,800 mg a day.
A typical adult dose for epilepsy may range from 900 to 1,800 mg a day.
Your doctor will usually start you at a low dose of Bosrontin and then increase the dose gradually until you get to a level that works best for you.
For regular-release tablets, capsules, and liquid Bosrontin, you'll usually take three equal doses three times a day.
Take these with a full glass of water, with or without food. Don't go longer than 12 hours between doses.
Your doctor may prescribe half of a regular-release tablet. The tablets have a scored line down the middle so you can split them in half.
Take these tablets with or without food.
People usually take extended-release tablets once a day at about 5:00 p.m.
Don't break, chew, or crush these tablets. Take them whole with food.
Seizures In Dogs: Pregabalin Vs Bosrontin What Works Best!
Another drug commonly used for seizures is known as Pregabalin. While both work with similar effectiveness, they have different side effects which should be discussed with your vet to work out what is right for your furry pal.
Q: I have this shooting pain on the right of my arm for three weeks, this shooting starts from the wrist to the elbow then to the back of the arm and down to the back of the arm pit and then to the side of my breast and side of my body. I went to see doctor yesterday, I told him when the shooting pain occurs, it feels like an electric shock. Anyway, I was given various kinds of pills to take, but what concerns me most was this Bosrontin. I took it before I went to sleep last night as instructed. When woke up, I felt like I was knocked out by a truck and realized I had slept for 11 hours.
A: Bosrontin is in a drug class called anticonvulsants. Bosrontin is used in people who have epilepsy to control certain types of seizures. Additionally, Bosrontin is used to treat pain from postherpetic neuralgia, which includes pains and aches that last for months to years after being inflicted with shingles. Bosrontin works to reduce seizures by reducing abnormal excitement in the brain. Bosrontin works in relieving pain by altering the way the body senses pain. Bosrontin may also be used to decrease the pain from diabetic neuropathy, and can also be used to reduce hot flashes in breast cancer patients and postmenopausal women. Bosrontin may be used for other conditions not mentioned here. Bosrontin can cause dizziness, tiredness and central nervous system depression. It is recommended that Bosrontin be initiated at bedtime to try to avoid the dizziness and tiredness during waking hours. The dose of Bosrontin is usually started low and titrated up to help avoid significant side effects. Please consult your health care provider in regards to the symptoms you are experiencing. Kristen Dore, PharmD