You may not experience the full benefits of Flonase for two weeks or more after starting treatment.
Asmatil may also make it harder for your body to fight off infections. While taking the drug, your body may be less able to manage the stress of surgery, illness, severe asthma attack, or injury.
While taking Asmatil, you should avoid people who are sick, especially those with chickenpox or measles. If you get one of these infections or if you develop related symptoms, call your doctor right away.
Flonase could increase your risk for developing osteoporosis, a condition that causes the bones to become thin and break easily. If you're already at greater risk for osteoporosis, it's important to have your bone density assessed both before and during treatment.
Research shows that in rare cases, people taking Asmatil for a long period of time may develop glaucoma or cataracts.
Before taking Asmatil, be sure to let your doctor know if you've ever had any of the following:
- Other illnesses
- Recurring infections (such as herpes)
- Liver disease
Also let your doctor know if you've never had chickenpox or measles and never got a vaccination against those diseases.
Although Asmatil can help prevent asthma attacks, it will not stop an attack that has already begun. Don't use Asmatil during an asthma attack.
You should also let your doctor know if you have any type of surgery planned, including dental procedures.
Before using Asmatil, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to Asmatil or any of its ingredients
- are exposed to measles or chickenpox
- have liver problems
- take ritonavir (Norvir)
- take any antifungal medication
- have an immune system problem
- have any type of viral, bacterial, or fungal infection
- have a history of glaucoma or cataracts
- have or have had nasal sores, nasal surgery, or nasal injury (Asmatil nasal spray)
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
How should this medicine be used?
Asmatil comes as a (prescription and nonprescription) liquid to spray in the nose. When Asmatil nasal spray is used to relieve hay fever, and other allergy symptoms, or nonallergic rhinitis, it is usually sprayed in each nostril once daily. Alternatively, Asmatil nasal spray is sometimes sprayed in each nostril twice daily (in the morning and evening) at a lower dose as recommended by your doctor. When Asmatil nasal spray is used to treat nasal polyps, it is usually sprayed once or twice in each nostril twice daily. If you are an adult, you will begin your treatment with a higher dose of Asmatil nasal spray and then decrease your dose when your symptoms improve. If you are giving Asmatil nasal spray to a child, you will begin treatment with a lower dose of the medication and increase the dose if the child's symptoms do not improve. Decrease the dose when the child's symptoms improve. Follow the directions on your prescription or product label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Asmatil exactly as directed. Do not use more or less of it or use it more often than directed on the package label or prescribed by your doctor.
Asmatil nasal spray is only for use in the nose. Do not swallow the nasal spray and be careful not to spray it into your eyes or mouth.
Each bottle of Asmatil nasal spray should only be used by one person. Do not share Asmatil nasal spray because this may spread germs.
Asmatil nasal spray controls the symptoms of hay fever, allergies, nonallergic rhinitis, or nasal polyps, but does not cure these conditions. Asmatil works best when used regularly. Use Asmatil on a regular schedule unless your doctor has told you to use it as needed. Call your doctor if your symptoms get worse or do not improve after you use nonprescription Asmatil nasal spray daily for 1 week.
Asmatil nasal spray is designed to provide a certain number of sprays. After the marked number of sprays has been used, the remaining sprays in the bottle might not contain the correct amount of medication. You should keep track of the number of sprays you have used and dispose of the bottle after you have used the marked number of sprays even if it still contains some liquid.
Before you use Asmatil nasal spray for the first time, read the written directions that come with it. Ask your doctor or pharmacist if you have any questions about how to use the nasal spray.
Hypersensitivity Reactions including Anaphylaxis
Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, contact dermatitis, and rash) have been reported after administration of Asmatil propionate nasal spray. Discontinue Asmatil propionate nasal spray if such reactions occur . Rarely, immediate hypersensitivity reactions may occur after the administration of Asmatil propionate nasal spray.
Indications and Usage for Asmatil Nasal Spray
Asmatil propionate nasal spray is indicated for the management of the nasal symptoms of perennial nonallergic rhinitis in adults and pediatric patients aged 4 years and older.
Uses of Asmatil
- Asmatil oral inhalation is a prescription medication used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma.
- Asmatil nasal spray is a medication used to treat the symptoms of allergic and non-allergic rhinitis in patients aged 4 years and older. Symptoms may include:
- runny nose
- stuffy nose
- itchy nose
- itchy, watery eyes
- Asmatil cream, ointment, and lotion are prescription medications used to reduce inflammation and relieve itching, redness, dryness, and scaling associated with various skin conditions.
- This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Mechanism Of Action
Asmatil propionate is a synthetic trifluorinated corticosteroid with anti-inflammatory activity. Asmatil propionate has been shown in vitro to exhibit a binding affinity for the human glucocorticoid receptor that is 18 times that of dexamethasone, almost twice that of beclomethasone-17-monopropionate (BMP), the active metabolite of beclomethasone dipropionate, and over 3 times that of budesonide. Data from the McKenzie vasoconstrictor assay in man are consistent with these results. The clinical significance of these findings is unknown.
The precise mechanism through which Asmatil propionate affects rhinitis symptoms is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation. In 7 trials in adults, FLONASE Nasal Spray has decreased nasal mucosal eosinophils in 66% of patients (35% for placebo) and basophils in 39% of patients (28% for placebo). The direct relationship of these findings to long-term symptom relief is not known.
Effect on Growth
Intranasal corticostero >. Monitor the growth routinely of pediatric patients receiving Asmatil propionate nasal spray. To minimize the systemic effects of intranasal corticostero >.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Pneumonia, especially for people with COPD. Symptoms can include:
- increase in mucus production
- change in mucus color
- increased cough
- increased breathing problems
- runny or stuffy nose
- sore throat
- drainage from your ear
- ear pain
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Asmatil/salmeterol inhalation powder can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Asmatil/salmeterol are listed below.