What Are Side Effects Associated with Using Aloprim?
Side effects associated with use of Aloprim, include the following:
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Severe skin rash. Symptoms can include:
- itchy hives (raised bumps on your skin)
- red or purple-colored spots on your skin
- scaly skin
- trouble breathing
- swelling of your face or throat
- lack of appetite
- weight loss
- right upper abdominal area pain or discomfort
- jaundice (dark-colored urine or yellowing of your skin or the whites of your eyes)
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Aloprim oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Patients should be informed of the following:
(1) They should be cautioned to discontinue ZYLOPRIM (Aloprim) and to consult their physician immediately at the first sign of a skin "rash, painful urination, blood in the urine, irritation of the eyes, or swelling of the lips or mouth. (2) They should be reminded to continue drug therapy prescribed for gouty attacks since optimal benefit of ZYLOPRIM (Aloprim) may be delayed for 2 to 6 weeks. (3) They should be encouraged to increase fluid intake during therapy to prevent renal stones. (4) If a single dose of ZYLOPRIM (Aloprim) is occasionally forgotten, there is no need to double the dose at the next scheduled time. (5) There may be certain risks associated with the concomitant use of ZYLOPRIM (Aloprim) and dicumarol, sulfinpyrazone, mercap-topurine, azathioprine, ampicillin, amoxicillin, and thiazide diuretics, and they should follow the instructions of their physician. (6) Due to the occasional occurrence of drowsiness, patients should take precautions when engaging in activities where alertness is mandatory. (7) Patients may wish to take ZYLOPRIM (Aloprim) after meals to minimize gastric irritation.
Dosage for recurrent kidney stones
Adult dosage (ages 18–64 years)
Typical dosage is 200–300 mg per day taken in a single or divided doses.
Child dosage (ages 0–17 years)
This medication hasn’t been studied and shouldn’t be used in people younger than 18 years for this condition.
Senior dosage (ages 65 years and older)
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.
Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.
- For people with kidney disease: Depending on how well your kidneys are working, your doctor will lower your dose. Your doctor will decide your dosage based on your creatinine clearance. This is a test that measures your kidney function.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Aloprim oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.
If you stop taking the drug suddenly or don’t take it at all: The uric acid levels in your blood or urine will stay high. If you have gout or kidney stones, you’ll still have symptoms of your condition.
If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms can include:
- skin rash
- changes in your liver function test results
- gout flare-up (if you have gout)
If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.
What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.
How to tell if the drug is working: Your doctor will test your uric acid levels to check if this drug is working. Your blood uric acid levels will decrease about 1–3 weeks after you start taking this drug. Your doctor will also ask you about how much fluids you drink and how much fluids you urinate.
Right after you start taking this drug, you may have gout flares. Over time, your symptoms of gout may start to go away.
Keep these considerations in mind if your doctor prescribes Aloprim oral tablet for you.
Getting the most from your treatment
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have a blood test to check that the level of uric acid has come down. This is often done a month or so after starting Aloprim.
- Remember, Aloprim should be taken every day to prevent a gout attack. It can take 2-3 months to become fully effective. It does not have any effect during a gout attack, although you should continue to take it regularly every day even if this happens.
- During the first few weeks of taking Aloprim, your blood levels of uric acid may rise for a short while before they fall. This can cause a gout attack. Your doctor will prescribe an anti-inflammatory treatment or colchicine tablets for you to take alongside Aloprim during this time.
- Treatment with Aloprim is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by a doctor.
- There are a number of lifestyle changes that you can make to help reduce the risk of having a gout attack. These include losing weight (if you are overweight), eating a healthy diet and not drinking much alcohol or sugar-sweetened soft drinks. Your doctor will advise you about the changes which could benefit you.
If you suspect an overdose, call 911 or contact a poison control center at (800) 222-1222.
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If you have had a number of gout attacks, your doctor will advise that you take a medicine every day to help prevent more attacks from occurring. Aloprim is the medicine which is most commonly prescribed for this. It helps to prevent gout attacks by reducing the levels of uric acid in your blood. As it is not a painkiller, it does not have any effect during a gout attack, so you will still need to take pain relief should you have any further attacks. In this case, your doctor will prescribe either an anti-inflammatory painkiller or colchicine for you to take alongside Aloprim.
Aloprim can also help prevent uric acid levels building up in some other conditions too. These include some types of kidney stones, and during some treatments for cancer. It works in these conditions by lowering the levels of uric acid in blood.
Rated Aloprim for Gout Report
Prescribed 100mg a day for gout pain and urate level fell but still suffered gout pains for about 5 months. When the dose was increased to 200mg a day I suffered from rashes, itches and very irritated eyelids. Have now gone 10 weeks without attack while taking 100mg a day. Keeping my fingers crossed. There is an alternative drug called "febuxostat".
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
- skin rash
- painful urination
- blood in the urine
- irritation of the eyes
- swelling of the lips or mouth
- fever, sore throat, chills, and other signs of infection
- loss of appetite
- unexpected weight loss
Aloprim may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Q: I've been prescribed Aloprim. What are its side effects?
A: The main side effect from Zyloprim (the generic name is Aloprim) is skin related. In more than 10 percent of people taking Zyloprim (Aloprim), skin rash; scaling skin; dark red, raised hives; or purple spot lesions have been reported, as has Stevens-Johnson syndrome (a possibly life-threatening skin condition where the cell death causes the epidermis to separate from the dermis). Less common side effects, in 1 to 10 percent of the population, include drowsiness, chills, fever, alopecia, nausea, vomiting, diarrhea, abdominal pain, gastritis, dyspepsia, and abnormal liver tests. If you aren't tolerating Aloprim and show any side effects, you should contact your doctor. Patti Brown, PharmD
Should I Avoid Any Food, Drink or Activity While Taking Aloprim?
Avoid drinking alcohol while taking Aloprim, as it may make your condition worse. Aloprim may impair your thinking or reaction time, so you should be especially careful when driving or performing any activity that requires you to be alert.
Your doctor may advise you to follow a special diet to help treat your condition.
Before taking this medicine
You should not take Aloprim if you are allergic to it.
To make sure Aloprim is safe for you, tell your doctor if you have ever had:
if you are receiving chemotherapy.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
What Other Drugs Interact with Aloprim?
If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Aloprim has no known severe interactions with any drugs.
Serious Interactions of Aloprim include:
Moderate Interactions of Aloprim include:
Mild Interactions of Aloprim include:
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
Aloprim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach