Cattrue, Docusate is a stool softener, it increases water retention in the intestines so it is easier to pass stool. Alaxa is a stimulant that is used to stop constipation by increasing motor activity in the intestine. Hope this helps.
For Healthcare Professionals
Applies to Alaxa: compounding powder, oral delayed release tablet, rectal enema, rectal suppository
Alaxa tablets bowel prep kit is contraindicated in the following conditions:
- Known allergies to polyethylene glycol or other components of the kit
- Gastrointestinal (GI) obstruction
- Bowel perforation
- Toxic colitis
- Toxic megacolon
There have been reports of generalized tonic-clonic seizures in patients with use of large volume (4 liter) PEG-based colon preparation products in patients with no prior history of seizures. The seizure cases were associated with severe vomiting, excessive beverage consumption and electrolyte abnormalities (for example, hyponatremia, hypokalemia). The neurologic abnormalities resolved with correction of fluid and electrolyte abnormalities. Therefore, Alaxa tablets bowel prep kit should be used with caution in patients using concomitant medications (such as diuretics) that increase the risk of electrolyte abnormalities or patients with known or suspected hyponatremia. Monitor baseline and post-colonoscopy laboratory tests (sodium, potassium, calcium, creatinine, and BUN) in these patients.
Response to Alaxa administration is the easiest measure to evaluate and probably the most important part of the test. Therefore, in certain cases it may not be necessary to study colonic motility after a meal. However, further validation of this recommendation is needed. A recent study showed that another possible method to elicit propagated colonic contractions is the intraluminal distention of the colon; the response, however, is not as consistent as the contractions elicited with Alaxa. 86 Abnormal propagation of the HAPCs may indicate a segmental motility disorder ( Figure 65-11 ), and absent motility and lack of postprandial response may indicate severe neuropathy ( Figure 65-12 ).
The stimulant >Alaxa , cascara) is the most frequently used type of over-the-counter laxative. They promote peristalsis presumably by direct action on the colonic mucosa and by stimulating intraluminal water and electrolyte secretion. They work quicker (several hours) than most other classes of laxatives. Early data suggested that stimulants may damage the enteric nervous system or cause dependency after repeated use but this is weakly supported by the literature. Melanosis coli, a black pigmentation staining of the colon, occurs with frequent use but is a benign condition and does not have any long-term consequences.
What do I need to tell my doctor BEFORE I take Alaxa Tablets?
- If you have an allergy to Alaxa or any other part of this medicine (Alaxa tablets).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Bowel block, belly pain, upset stomach, rectal bleeding, throwing up, or change in bowel habits lasting longer than 2 weeks.
- If you cannot swallow without chewing.
This is not a list of all drugs or health problems that interact with this medicine (Alaxa tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (Alaxa tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Can I use Alaxa after surgery?
It’s quite common to have constipation after surgery. Using a laxative may help.
If you have constipation after an operation, it’s better to use lactulose because it is gentler than Alaxa. You can get it on prescription or buy it from pharmacies.
• Instruct patient to swallow (not chew) enteric-coated tablets no sooner than 1 hour before or after ingesting antacids or dairy products. Tell him not to chew tablets.
• Advise patient not to use Alaxa or other laxatives habitually because this may lead to laxative dependence.
• Suggest other ways to prevent constipation, such as by eating more fruits, vegetables, and whole grains to increase dietary bulk and by drinking 8 to 10 glasses of water daily.
• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.