Lioresyl tablets


  • Active Ingredient: Baclofen
  • 25 mg, 10 mg
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What is Lioresyl?

The active ingredient of Lioresyl brand is baclofen. Baclofen is a muscle relaxer and an antispastic agent. Baclofen Tablets, USP 10 mg and 20 mg contain the following inactive ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, microcrystalline cellulose and pregelatinized starch.

Used for

Lioresyl is used to treat diseases such as: Alcohol Withdrawal, Cerebral Spasticity, Cervical Dystonia, Chronic Spasticity, Cluster-Tic Syndrome, Dystonia, Hiccups, Huntington's Disease, Migraine Prevention, Muscle Spasm, Muscle Twitching, Neuralgia, Periodic Limb Movement Disorder, Spasticity, Spinal Spasticity, Temporomandibular Joint Disorder, Trigeminal Neuralgia.

Side Effect

Possible side effects of Lioresyl include: low blood pressure; unusual nervousness or restlessness; hallucinations (seeing or hearing things that are not there); fainting; false sense of well-being.

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What Is Lioresyl?

Lioresyl is a prescription drug used to treat muscle spasms from multiple sclerosis and Huntington's disease as well as spinal cord injuries and spinal cord diseases.

Medical experts do not recommend Lioresyl for muscle spasms caused by rheumatoid arthritis, cerebral palsy, Parkinson's disease, or stroke, because research to date does not support such use.

Lioresyl is an antispastic muscle relaxant. Researchers don't know exactly how Lioresyl works; however, in general, it blocks nerve signals from muscles at the level of the spinal cord and it may also depress the central nervous system.

The Food and Drug Administration (FDA) approved Lioresyl in 1977 under the brand name Lioresal, which was made by Novartis. The FDA approved generic Lioresyl in the 1980s.

Today, only generic versions of Lioresyl are available.

A case report published in Therapeutic Advances in Psychopharmacology in 2014 suggested that Lioresyl might be effective for treating marijuana dependence, particularly for those who have used the drug heavily for a long time. The research also showed that Lioresyl may help reduce withdrawal symptoms as well as the effects of marijuana.

A separate study, published in the Journal of Neuroscience in 2014, found that Lioresyl may also help people with drug addiction avoid possible triggers and prevent relapse. The drug works by interfering with the brain's early response to drug cues.

Why Lioresyl for Opiate Withdrawal?

For people detoxing from opioids or opiates, it is important to avoid trying to detox on your own. Some options can help you feel more comfortable and also increase your chances of detoxing successfully. Contact The Recovery Village to learn more about our detox and treatment programs.

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Mechanism of Injury

The apparent absence of significant hepatotoxicity from Lioresyl may be due to its minimal hepatic metabolism (

15%) and rapid urinary excretion.

Why it’s used

Lioresyl is used to treat muscle spasms. It may be used as part of a combination therapy. This means you may need to take it with other medications.

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