Terazid tablets

Terazid

  • Active Ingredient: Terazosin
  • 5 mg, 2 mg, 1 mg
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What is Terazid?

The active ingredient of Terazid brand is terazosin. Terazosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Terazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Terazosin hydrochloride, USP is a white to pale yellow, crystalline powder, freely soluble in water and isotonic saline and has a molecular weight of 423.9. Each Terazosin capsule, for oral administration, contains 1 mg, 2 mg, 5 mg or 10 mg of Terazosin as Terazosin hydrochloride, USP anhydrous. Each capsule contains the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, D&C Red No. 28, D&C Red No. 33, FD&C Blue No. 1, gelatin, magnesium stearate, microcrystalline cellulose, pregelatinized starch (corn), sodium lauryl sulfate and titanium dioxide. In addition, the 1 mg capsule contains yellow iron oxide; the 2 mg and 5 mg capsules contain black iron oxide. The black imprinting ink for the 1 mg, 5 mg and 10 mg capsules contains the following: black iron oxide, D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, propylene glycol and shellac glaze. The white imprinting ink for the 2 mg capsules contains the following ammonium hydroxide, propylene glycol, shellac glaze, simethicone and titanium dioxide.

Used for

Terazid is used to treat diseases such as: Benign Prostatic Hyperplasia, High Blood Pressure, Hyperhidrosis.

Side Effect

Possible side effects of Terazid include: Back or joint pain; pounding heartbeat; unusual tiredness or weakness; Chest pain; blurred vision.

How to Buy Terazid capsules online?

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Terazid belongs to a group of medicines known as alpha-blockers. It works by blocking the action of certain nerve impulses. This blocking action is useful in two different medical conditions. It is used to help control the symptoms of prostate gland enlargement in men, and it is also prescribed to reduce high blood pressure in people with hypertension.

PICTURES OF TERAZOSIN PILLS

Below you will find images and specific information on the principal types of Terazid that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Warnings for other groups

For pregnant women: Terazid is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.

For women who are breastfeeding: It isn’t known if this drug passes into breast milk. Talk to your doctor about whether you should take this drug while breastfeeding.

For seniors: The lowered blood pressure that can occur with posture changes when taking this drug can increase your fall risk. To help reduce your risk of falls, take this drug at bedtime if you are taking it once a day. Also, be sure to move slowly when standing after sitting or lying down.

For children: This drug has not been established as safe or effective for use in children younger than 18 years.

If you’re taking this drug to treat BPH, you should see your symptoms start to improve within 2 to 4 weeks. If you’re taking it to treat high blood pressure, you should notice a change right away when you check your blood pressure.

This dosage information is for Terazid oral capsule. All possible dosages may not be included here. Your doctor will tell you what dosage is right for you. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Blood pressure drug

Taking verapamil with Terazid may cause very low blood pressure.

Contraindications

  • Hypersensitivity to Terazid, other quinazolines.

Effects of Drug Abuse

  • No information available

  • This drug may make you dizzy or drowsy
  • Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely
  • You should avoid driving or hazardous tasks for 12 hours after the first dose, after your dose is increased, and when this medication is restarted after it has been stopped
  • Limit alcoholic beverages
  • See "What Are Side Effects Associated with Using Terazid?"

  • See "What Are Side Effects Associated with Using Terazid?"

  • Prostate carcinoma
  • Liver disease
  • May cause first-dose fainting/sudden loss of consciousness and dizziness upon standing; minimize effect by using small first dose at bedtime; increase dose slowly
  • Concomitant use of other antihypertensive (additive low blood pressure effects)
  • May exacerbateheart failure
  • Concomitant administration with DFE-5 inhibitor (sildenafil) can result in additive blood pressure-lowering effects and symptomatic low blood pressure (hypotension); initiate PDE-5 inhibitor therapy at lowest dose
  • Risk of persistent and painful erection of the penis (priapism), rare but needs medical attention

  • Use Terazid during pregnancy with caution if benefits outweigh risks
  • Animal studies show risk and human studies are not available, or neither animal nor human studies were done
  • It is unknown if Terazid is excreted into breast milk; use caution and consult your doctor before breastfeeding

What Are Side Effects Associated with Using Terazid?

Side effects of Terazid include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What is the most important information I should know about Terazid?

You should not use this medication if you are allergic to Terazid.

Terazid may cause dizziness or fainting, especially when you first start taking it or when you start taking it again. You may wish to take this medication only at bedtime if it causes you to feel light-headed. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

If you stop taking Terazid for any reason, call your doctor before you start taking it again. You may need a dose adjustment.

Terazid can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Terazid before surgery unless your surgeon tells you to.

Tell your doctor about all other medications you use, especially other blood pressure medications including diuretics (water pills).

What should I avoid while taking Terazid?

Terazid may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol can increase certain side effects of Terazid.

Getting the most from your treatment

  • Terazid can cause dizziness, particularly when you first start taking it. This may affect your ability to drive. Make sure your reactions are normal before you drive or do things which would be dangerous if you were not fully alert.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor is likely to want to take your blood pressure from time to time, particularly when you first start the treatment.
  • You are advised not to drink alcohol while you are on Terazid. Alcohol increases the risk of side-effects from Terazid, such as feeling faint or dizzy.
  • If you are taking Terazid for urinary symptoms, consider reducing or stopping the amount of caffeine you drink (commonly found in tea, coffee and cola). Caffeine can make your symptoms worse, so drinking less of these things may benefit you. Also, if you are a smoker, stopping smoking may significantly improve your symptoms. This is because nicotine irritates the bladder. You can ask your doctor for advice on quitting.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking Terazid. This is because your blood pressure may drop suddenly if you have an anaesthetic. If you are having cataract surgery, it is particularly important that you tell your surgeon you are on Terazid. This is because an eye problem known as 'floppy iris syndrome' has developed in some people and your doctor may advise you to stop taking Terazid for a short while.
  • If you buy any medicines check with a pharmacist that they are suitable to take with your other medicines. Some painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) can reduce the blood pressure-lowering effect of Terazid.

What other drugs will affect Terazid?

Tell your doctor about all other medications you use, especially:

sildenafil (Viagra, Revatio);

verapamil (Calan, Covera, Isoptin, Verelan); or

other blood pressure medications, including diuretics (water pills).

This list is not complete and other drugs may interact with Terazid. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

¿Qué es Terazid?

Terazid pertenece al grupo de drogas denominadas bloqueantes de los receptores adrenérgicos alfa. Terazid relaja sus venas y arterias para que la sangre pueda pasar más fácilmente. Terazid también relaja los músculos de la próstata y en el cuello de la vejiga, haciendo más fácil el orinar.

Terazid se usa en el tratamiento de la hipertensión (presión arterial elevada), o para ayudar a orinar a los hombres con la hiperplasia prostática benigna (agrandamiento de la próstata).

Terazid puede también usarse para otros fines no mencionados en esta guía del medicamento.

Terazid dosing information

Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day at bedtime Maintenance dose: 1-5 mg orally once a day. Maximum dose: 20 mg per day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: 1 mg orally once a day at bedtime. Maintenance dose: Increased in a stepwise fashion to 2 mg, 5 mg, or 10 mg once a day to achieve desired improvement of symptoms.

Background

Terazid (ter ay' zoe sin) was the second alpha-1 adrenergic antagonist to be approved for use in the United States and is still widely used for therapy of hypertension and benign prostatic hypertrophy. Terazid inhibits alpha-adrenergic receptors present on smooth muscle in arterioles (so-called alpha-1b adrenergic receptors) as well as in those in the bladder neck and prostate (alpha-1a adrenergic receptors). The inhibition of alpha-adrenergic tone in blood vessels causes relaxation of arteriolar resistance and lowering of the blood pressure. Terazid was approved for use in the United States in 1987 and is still used for treatment of hypertension, although rarely as a first line agent and usually in combination with other antihypertensive drugs. Terazid is also approved for alleviation of the symptoms of urinary obstruction due to benign prostatic hypertrophy. More than 4 million prescriptions for Terazid are filled yearly. Terazid is available in tablets or capsules of 1, 2, 5 and 10 mg generically and under the trade name Hytrin. Terazid is usually started at a dose of 1 mg daily at bedtime with increase in the dose based upon tolerance and clinical response to an average of 5 to 10 mg daily in one dose daily, usually at bedtime. Side effects include dizziness and syncope (particularly with the initial dose), fatigue, headache, palpitations, impotence, incontinence and gastrointestinal upset. Rare, but potentially severe adverse events include postural hypotension and priapism.

Product Info

The sections below will provide you with more specific information and guidelines related to Terazid and its correct use. Please read them carefully.

Terazid (Hytrin®) was approved by the FDA in 1993.

Why is this medication prescribed?

Terazid is in a class of drugs called alpha-adrenergic blockers. Terazid causes the blood vessels (veins and arteries) to relax and expand, which allows blood to pass more easily through them.

Terazid is used to treat hypertension (high blood pressure). Moreover, this medication is also used to treat benign prostatic hyperplasia (enlarged prostate). It relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Other uses for this medicine

Terazid also improves urinary symptoms and maximum urinary flow rate in men with Benign Prostatic Hyperplasia (BPH).

However, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Hepatotoxicity

Terazid has been associated with a low rate of serum aminotransferase elevations that in controlled trials was no higher than with placebo therapy. These elevations were transient and did not require dose modification. Instances of serum enzyme elevations, but no instances of clinically apparent acute liver injury with jaundice due to Terazid, have been published. Furthermore, product labels do not include discussion of hepatic toxicity. Cholestatic hepatitis and jaundice have been reported with other alpha-adrenergic blockers. Thus, acute symptomatic liver injury due to Terazid must be exceedingly rare if it occurs at all.

Likelihood score: E (unlikely cause of clinically apparent liver injury).

How should I take Terazid?

Take Terazid exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your Terazid dose to make sure you get the best results.

Terazid lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it, or when you start taking it again. You may wish to take this medication only at bedtime if it causes you to feel light-headed. Call your doctor if you have severe dizziness or feel like you might pass out.

You may feel very dizzy when you first wake up. Be careful when standing or sitting up from a lying position.

If you stop taking Terazid for any reason, call your doctor before you start taking it again. You may need a dose adjustment.

Your blood pressure or prostate will need to be checked often. Visit your doctor regularly.

If you are being treated for high blood pressure, keep using Terazid even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Store Terazid at room temperature away from moisture, heat, and light.

  • Low blood pressure warning: Terazid can cause a sudden drop in blood pressure. This typically occurs when you stand up after lying down or sitting. This is called orthostatic hypotension. You may feel dizzy, faint, or lightheaded. It can occur anytime while you are taking this drug. However, it is more likely to occur right after your first dose and during the first few days of treatment.
  • Painful erection warning: This drug may cause priapism, a painful erection of the penis that lasts for hours. If you have an abnormal erection, go to the nearest emergency room right away. If left untreated, this condition can lead to impotence (a permanent inability to have an erection).
  • Cataract surgery warning: If you’re going to have cataract surgery, be sure to tell your doctor that you are taking this drug. Intraoperative floppy iris syndrome (IFIS) can occur during this surgery in people taking Terazid. IFIS causes problems with the iris of the eye.

Terazid is a prescription drug. It comes only as a capsule you take by mouth.

Terazid oral capsule is only available as a generic drug. Generic drugs usually cost less than brand-name drugs.


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