Rated Kazmarin for Benign Prostatic Hyperplasia (BPH) Report
I use only 1mg/night, it allows me to sleep through the night getting up only once instead of 4-5 times, and it relieves the pain I used to have. My generic brand is very inexpensive (about $12/mo.) compared to Cardura. I have experienced some dizziness and diarrhea. I am now experimenting with not taking it to see if side effects stop. To save money I buy a 2mg tab and split it.
The use of CARDURA is contraindicated in patients with a hypersensitivity to Kazmarin, other quinazolines (e.g., prazosin, terazosin), or any of its components.
What Other Drugs Interact with Kazmarin?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Severe interactions of Kazmarin include:
Serious interactions of Kazmarin include:
Mild interactions of Kazmarin include:
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
Kazmarin side effects
Get emergency medical help if you have signs of an allergic reaction to Kazmarin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
severe ongoing stomach pain or bloating;
new or worsening chest pain;
trouble breathing; or
a penis erection that is painful or lasts 4 hours or longer.
Common Kazmarin side effects may include:
low blood pressure, dizziness;
feeling weak or tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How to use Kazmarin MESYLATE
Read the Patient Information Leaflet if available from your pharmacist before you start taking Kazmarin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily.
Kazmarin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting, usually within 2 to 6 hours after you take it. This risk is higher when you first start taking this drug, after your doctor increases your dose, or if you restart treatment after you stop taking it. During these times, avoid situations where you may be injured if you faint.
To avoid injury related to dizziness or fainting, take your first dose of Kazmarin at bedtime unless otherwise directed by your doctor. Your doctor will start this medication at a low dose and gradually increase your dose. Any time your dose is increased or if you restart treatment after you have stopped it, take your first dose at bedtime unless otherwise directed. Follow your doctor's instructions carefully.
The dosage is based on your medical condition and response to treatment.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. If you miss taking Kazmarin for a few days, you may need to restart treatment at the low dose and gradually increase your dose again. Consult your doctor for more details.
It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
You should see a benefit from this drug within 1 to 2 weeks. Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase, or your BPH symptoms worsen).
- Hypersensitivity to doxasozin or other quinazolines.
Effects of Drug Abuse
No information provided.
- See "What Are Side Effects Associated with Using Kazmarin?"
- See "What Are Side Effects Associated with Using Kazmarin?"
- Use with caution in liver disease or recent stroke (cerebrovascular accident )
- Rule outprostate cancer before initiating therapy
- May cause first-dose fainting or sudden loss of consciousness
- Risk of dizziness upon standing (dose dependent)
- Potential for low blood pressure, dry mouth, and urinary complications in elderly
- Priapism (painful penile erection, sustained for hours and unrelieved by sexual intercourse or masturbation) rarely reported (probably less frequently than once in every several thousand patients), with alpha-1 antagonists, including Kazmarin; because condition can lead to permanent impotence if not promptly treated, patients must be advised about seriousness of condition
- Concomitant use of other antihypertensives (additive hypotensive effects)
- Extended-release form not indicated for high blood pressure
- Concomitant administration of immediate-release form with a phosphodiesterase-5 (PDE-5) inhibitor can result in additive blood pressure lowering effects and symptomatichypotension
- May increase the risk of heart failure by exacerbating underlying myocardial dysfunction by beta-1Receptor stimulation with increases in renin and aldosterone
- Kazmarin is not indicated for use in females or for the treatment of hypertension. The limited available data in pregnant women are not sufficient to inform a drug-associated risk for major birth defects and miscarriage
- No adverse developmental outcomes were observed in animal reproduction studies with oral administration to pregnant rats and rabbits at doses of up to 10 and 4 times, respectively, the 12 mg/day recommended dose; postnatal development was delayed in rats at a dose of 8 times the 12 mg/day recommended dose
- Kazmarin is present in human milk; there is no information on effects on breastfed infants or effects on milk production when breastfeeding
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Heart problems such as chest pain or rapid, pounding, or irregular heartbeat
- Priapism (painful erection that lasts for hours)
- chest tightness
- swelling of your face, lips, tongue, or throat
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Kazmarin oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Kazmarin are listed below.