Doxane tablets


  • Active Ingredient: Doxazosin
  • 4 mg, 2 mg, 1 mg
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What is Doxane?

The active ingredient of Doxane brand is doxazosin. Doxazosin is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Used for

Doxane is used to treat diseases such as: Benign Prostatic Hyperplasia, High Blood Pressure, Raynaud's Syndrome.

Side Effect

Possible side effects of Doxane include: cloudy urine; Acid or sour stomach; feeling of warmth; trouble sleeping; heartburn; Abdominal or stomach pain.

How to Buy Doxane tablets online?

To purchase Doxane online - simply click on the "Buy Now" button in the top and follow on to our store. Payment and Order takes a few minutes, and all steps are obvious. We do not require a medical prescription plus also we have many procedures of payment. Considering all the details of fast delivery and confidentiality, then you may read on the applicable pages on the links in the navigation menu.

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ВїQuГ© otra informaciГіn de importancia deberГ­a saber?

Si usted estГЎ tomando las tabletas de liberaciГіn lenta de Doxanea, podrГ­a notar algo que se parece una tableta en sus heces. Esto es la cubierta vacГ­a de la tableta y eso no significa que no obtuvo la dosis completa del medicamento.

Cumpla con todas las citas con su doctor y el laboratorio. Si estГЎ tomando Doxanea para controlar su hipertensiГіn, deberГЎ controlarse la presiГіn arterial de manera regular para determinar la respuesta de su cuerpo a la Doxanea.

No deje que otras personas tomen su medicamento. PregГєntele al farmacГ©utico cualquier duda que tenga sobre cГіmo renovar esta prescripciГіn.

Es importante que Ud. mantenga una lista escrita de todas las medicinas que Ud. estГЎ tomando, incluyendo las que recibiГі con receta mГ©dica y las que Ud. comprГі sin receta, incluyendo vitaminas y suplementos de dieta. Ud. debe tener la lista cada vez que visita su mГ©dico o cuando es admitido a un hospital. TambiГ©n es una informaciГіn importante en casos de emergencia.

What should I avoid while taking Doxane?

Doxane may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol with this medicine can cause side effects.

Dosage for high blood pressure

Generic: Doxane

  • Form: oral immediate-release tablet
  • Strength: 1 mg, 2 mg, 4 mg, and 8 mg

Brand: Cardura

  • Form: oral immediate-release tablet
  • Strengths: 1 mg, 2 mg, 4 mg, and 8 mg

Adult dosage (ages 18–64 years)

  • Typical starting dosage: 1 mg once daily.
  • Dosage increases: Based on your blood pressure, your doctor may increase your dosage to a maximum of 16 mg once daily.

Child dosage (ages 0–17 years)

A safe and effective dose hasn’t been established for this age group.

Senior dosage (ages 65 years and older)

Your body may process this drug more slowly. Your doctor may start you on a lowered dose so that too much of this drug doesn’t build up in your body. Too much of the drug in your body can be toxic.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Doxane oral tablet is a long-term drug treatment. It comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all: Your symptoms may not improve or they may get worse over time. If your condition improved while taking the medication regularly and you stop taking Doxane suddenly, your symptoms may come back.

If you miss doses or don’t take the drug on schedule: You may not see a full benefit of this medication. If you double up your dose or take it too close to your next scheduled time, you may be at higher risk of experiencing serious side effects.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

  • lightheadedness
  • dizziness
  • fainting
  • seizure
  • drowsiness

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: If you miss a dose, take it as soon as you can. However, if it’s just a few hours until your next dose, wait and take a single dose.

Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working:

  • For BPH: You should have an easier time urinating and experience fewer symptoms of obstruction and irritation.
  • For high blood pressure: Your blood pressure should be lower. High blood pressure doesn’t often have symptoms, so you may need to have your blood pressure checked to know if your pressure is lower.

Keep these considerations in mind if your doctor prescribes Doxane oral tablet for you.

Storage And Handling

CARDURA (Doxane mesylate) is available as scored tablets for oral administration. Each tablet contains Doxane mesylate equivalent to 1 mg (white), 2 mg (yellow), 4 mg (orange) or 8 mg (green) of the active constituent, Doxane.

Recommended Storage: Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) .

Distributed by: Roerig Division of Pfizer Inc., NY, NY 10017. Revised: June 2016

Studies in rats showed reduced fertility in males treated with Doxane at oral doses of 20 (but not 5 or 10) mg/kg/day, about 4 times the AUC exposures obtained with a 12 mg/day human dose. This effect was reversible within two weeks of drug withdrawal. There have been no reports of any effects of Doxane on male fertility in humans.

Why is this medication prescribed?

Doxane is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency. It is also used alone or in combination with other medications to treat high blood pressure. Doxane is in a class of medications called alpha-blockers. It relieves the symptoms of BPH by relaxing the muscles of the bladder and prostate. It lowers blood pressure by relaxing the blood vessels so that blood can flow more easily through the body.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

Missed Dose of Doxane

If you miss a dose of Doxane, take it as soon as you remember.

However, skip the missed dose if it is almost time for your next dose.

Don't take extra amounts of the medication to make up for a missed dose.

If you miss your scheduled doses for several days, contact your doctor before restarting the medication.

Blood pressure medications

Combining Doxane with any drug that lowers your blood pressure can increase your risk for lowering your blood pressure too much. Examples of drugs that lower your blood pressure are:

  • aldosterone antagonists, such as spironolactone and eplerenone
  • angiotensin-converting enzyme (ACE) inhibitors, such as benazepril, lisinopril, enalapril, and fosinopril
  • angiotensin receptor blockers (ARBs), such as losartan, candesartan, and valsartan
  • beta-blockers, such as atenolol, bisoprolol, metoprolol, and propranolol
  • calcium channel blockers such as amlodipine, nifedipine, nicardipine, diltiazem, and verapamil
  • centrally acting adrenergic agents, such as clonidine, guanfacine, and methyldopa
  • direct renin inhibitors, such as aliskiren
  • diuretics such as amiloride, chlorthalidone, furosemide, and metolazone
  • vasodilators such as hydralazine and minoxidil
  • nitrates, such as isosorbide mononitrate, isosorbide dinitrate, and nitroglycerin transdermal patch

Combining Doxane with drugs that increase your blood pressure can cancel the effects of both medications. Examples of these drugs include:

  • symphathomimetics (decongestants) such as pseudoephedrine, oxymetazoline, phenylephrine
  • erythropoiesis-stimulating agents (red blood cell production stimulators) such as darbepoetin alfa and epoetin alfa
  • contraceptives (birth control) such as ethinyl estradiol and ethinyl estradiol/levonorgestrel

Doxane Interactions

Some drugs that may interact with Doxane include:

  • Erectile dysfunction medicines, including sildenafil (Viagra, Revatio), tadalafil (Cialis), and vardenafil (Levitra)
  • Hepatitis C protease inhibitor (Boceprevir)
  • Monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil) and tranylcypromine (Parnate)

You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking.

Antes de comenzar a tomar Doxanea:

  • dГ­gale a su doctor y a su farmacГ©utico si usted es alГ©rgico a la Doxanea, prazosin (Minipress), terazosina, otros medicamentos, o a alguno de los ingredientes que contienen las tabletas o tabletas de liberaciГіn lenta de Doxanea. Pida a su farmacГ©utico una lista de los ingredientes.
  • dГ­gale a su doctor y a su farmacГ©utico quГ© medicamentos con y sin prescripciГіn, vitaminas, suplementos nutricionales y productos fabricados a base de hierbas estГЎ tomando o planea tomar. AsegГєrese de mencionar los siguientes: antihistamГ­nicos; claritromicina (Biaxin, en Prevpac); ipratropium (Atrovent, en Combivent); itraconazol (Onmel, Sporanox); ketoconazol (Nizoral); medicamentos para la disfunciГіn erectil (ED, por su sigla en inglГ©s) como sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), o vardenafil (Levitra, Staxyn); medicamentos para la hipertensiГіn; medicamentos para el HIV/AIDS incluyendo atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, en Kaletra), o saquinavir (Invirase); medicamentos para la enfermedad de colon irritable, mareos por viaje, enfermedad de Parkinson, Гєlceras, o problemas urinarios; nefazodona; telitromicina (Ketek); y voriconazol (Vfend). Su doctor podrГ­a necesitar cambiar la dosis de sus medicamentos o vigilarle cuidadosamente para evitar efectos secundarios.
  • dГ­gale a su doctor si tiene angina (dolor en el pecho); baja presiГіn arterial; si usted tiene o alguna vez ha tenido baja presiГіn arterial despuГ©s de tomar medicamentos; o si usted tiene o alguna vez ha tenido cГЎncer de prГіstata o enfermedad al hГ­gado. Si usted estГЎ tomando las tabletas de liberaciГіn lenta, dГ­gale a su doctor si tiene estreГ±imiento (constipaciГіn), sГ­ndrome del intestino corto (un trastorno donde mГЎs de la mitad del intestino delgado ha sido retirado a travГ©s de una cirugГ­a o ha sido daГ±ado por una enfermedad), o estrechamiento o bloqueo de los intestinos.
  • dГ­gale a su doctor si estГЎ embarazada, tiene planes de quedar embarazada o si estГЎ amamantando. Si queda embarazada mientras toma este medicamento, llame a su doctor de inmediato.
  • hable con su mГ©dico sobre los riesgos y beneficios de tomar esta medicina si usted tiene 65 aГ±os de edad o mГЎs. Los adultos mayores no suelen tomar Doxanea para tratar la presiГіn arterial alta porque no es tan seguro y efectivo que otro medicamentos que pueden usarse para tratar la misma condiciГіn.
  • si va a ser sometido a cualquier cirugГ­a, incluyendo la dental, dГ­gale al doctor o dentista que usted estГЎ tomando Doxanea. Si usted necesitar tener una cirugГ­a en sus ojos en cualquier momento durante el tratamiento, asegГєrese de decirle a su doctor que usted estГЎ tomando o ha tomado Doxanea.
  • la Doxanea puede causar somnolencia y mareos. No conduzca automГіviles, no maneje maquinaria pesada ni practique actividades peligrosas hasta 24 horas despuГ©s de haber tomado el medicamento por primera vez o despuГ©s de que el mГ©dico haya aumentado su dosis.
  • usted debe saber que este medicamento puede provocar mareos, nГЎuseas y desmayos al levantarse demasiado rГЎpido. Este sГ­ntoma es mГЎs comГєn cuando usted reciГ©n ha comenzado a tomar el medicamento, al aumentar la dosis, o si su tratamiento es interrumpido por un perГ­odo mГЎs largo que unos pocos dГ­as. Para evitar este problema, levГЎntese de la cama lentamente, apoyando los pies en el piso durante algunos minutos antes de ponerse de pie. Si estos sГ­ntomas se presentan, siГ©ntese o acuГ©stese. Si estos sГ­ntomas no mejoran, llame a su doctor.

La Doxanea puede provocar efectos secundarios. DГ­gale a su doctor si cualquiera de estos sГ­ntomas o aquellos enumerados en la secciГіn de ADVERTENCIA se vuelven graves o no desaparecen:

  • dolor de cabeza
  • cansancio
  • inflamaciГіn de las manos, pies, tobillos o pantorrillas
  • respiraciГіn entrecortada
  • aumento de peso
  • dolor o debilidad en los mГєsculos o en las articulaciones
  • visiГіn anormal
  • secreciГіn nasal
  • disminuciГіn de la capacidad sexual


Experience with CARDURA overdosage is limited. Two adolescents, who each intentionally ingested 40 mg CARDURA with diclofenac or acetaminophen, were treated with gastric lavage with activated charcoal and made full recoveries. A two-year-old child who acc >

The oral LD50 of Doxane is greater than 1000 mg/kg in mice and rats. The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of fluid. As Doxane is highly protein bound, dialysis would not be indicated.

Parkinson’s disease drug

Taking levodopa with Doxane can increase your risk of low blood pressure when standing.


The use of CARDURA is contraindicated in patients with a hypersensitivity to Doxane, other quinazolines (e.g., prazosin, terazosin), or any of its components.

Plasma elimination of Doxane is biphasic, with a terminal elimination half-life of about 22 hours. Steady-state studies in hypertensive patients given Doxane doses of 2 to 16 mg once daily showed linear kinetics and dose proportionality. In two studies, following the administration of 2 mg orally once daily, the mean accumulation ratios (steady-state AUC vs. first-dose AUC) were 1.2 and 1.7. Enterohepatic recycling is suggested by secondary peaking of plasma Doxane concentrations.

In a study of two subjects administered radiolabelled Doxane 2 mg orally and 1 mg intravenously on two separate occasions, approximately 63% of the dose was eliminated in the feces and 9% of the dose was found in the urine. On average only 4.8% of the dose was excreted as unchanged drug in the feces and only a trace of the total radioactivity in the urine was attributed to unchanged drug.

Getting the most from your treatment

  • Doxane can make you feel dizzy, particularly when you first start taking it. Make sure your reactions are normal before you drive or use tools or machines which would be dangerous if you are not fully alert.
  • You are advised not to drink alcohol while you are on Doxane. Alcohol will increase the side-effects of Doxane, such as feeling faint and dizzy.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • If you are having an operation or medical treatment, tell the person carrying out the treatment that you are taking Doxane. This is because your blood pressure may drop suddenly if you have an anaesthetic. If you are having cataract surgery, it is particularly important that you tell your eye surgeon that you are on Doxane. This is because an eye problem known as 'floppy iris syndrome' has developed in some people taking medicines similar to Doxane, so your doctor may advise you to stop taking it for a short while.
  • If you buy any medicines check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers (called NSAIDs) can reduce the blood pressure-lowering effect of Doxane.

ВїPara cuГЎles condiciones o enfermedades se prescribe este medicamento?

La Doxanea es usada en hombres para tratar los sГ­ntomas de la prГіstata agrandada (hiperplasia prostГЎtica benigna o BHP, por su sigla en inglГ©s), que incluyen dificultad para orinar (vacilaciГіn, goteo, corriente dГ©bil y vaciado incompleto de la vejiga), dolor al orinar y necesidad de orinar con frecuencia y urgencia. Es tambiГ©n usada sola o en combinaciГіn con otros medicamentos para tratar la hipertensiГіn. La Doxanea pertenece a una clase de medicamentos llamados alfabloqueadores. Alivia los sГ­ntomas de la hiperplasia al relajar los mГєsculos de la vejiga y de la prГіstata. Disminuye la presiГіn arterial al relajar los vasos sanguГ­neos para que la sangre pueda fluir de manera mГЎs eficiente a travГ©s del cuerpo.

La hipertensiГіn arterial es una condiciГіn comГєn y cuando no se trata, puede causar daГ±os en el cerebro, el corazГіn, los vasos sanguГ­neos, los riГ±ones y otras partes del cuerpo. El daГ±o a estos Гіrganos puede causar enfermedades del corazГіn, un infarto, insuficiencia cardГ­aca, apoplejГ­a, insuficiencia renal, pГ©rdida de la visiГіn y otros problemas. AdemГЎs de tomar medicamentos, hacer cambios de estilo de vida tambiГ©n le ayudarГЎ a controlar su presiГіn arterial. Estos cambios incluyen comer una dieta que sea baja en grasa y sal, mantener un peso saludable, hacer ejercicio al menos 30 minutos casi todos los dГ­as, no fumar y consumir alcohol con moderaciГіn.

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