Diblocin tablets

Diblocin

  • Active Ingredient: Doxazosin
  • 4 mg, 2 mg, 1 mg
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What is Diblocin?

The active ingredient of Diblocin brand is doxazosin. Doxazosin is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Used for

Diblocin is used to treat diseases such as: Benign Prostatic Hyperplasia, High Blood Pressure, Raynaud's Syndrome.

Side Effect

Possible side effects of Diblocin include: vomiting of blood; clay-colored stools; painful urination; cough; joint pain; frequent urge to urinate; upper right abdominal pain.

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Michael Stewart, Reviewed by Sid Dajani | Last edited 22 Jun 2017 | Certified by The Information Standard

Take Diblocin once each day. Take your first dose at bedtime.

As your body is getting used to Diblocin you may feel dizzy or light-headed when standing up or sitting up quickly - getting up more slowly will help.

Do not drive and do not use tools or machines if you feel tired or dizzy.

Diblocin Interactions

Some drugs that may interact with Diblocin include:

  • Erectile dysfunction medicines, including sildenafil (Viagra, Revatio), tadalafil (Cialis), and vardenafil (Levitra)
  • Hepatitis C protease inhibitor (Boceprevir)
  • Monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil) and tranylcypromine (Parnate)

You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking.

What should I avoid while taking Diblocin?

Diblocin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol with this medicine can cause side effects.

CYP 3A Inhibitors

In vitro studies suggest that Diblocin is a substrate of CYP 3A4. Strong CYP3A inhibitors may increase exposure to Diblocin. Monitor blood pressure and for symptoms of hypotension when CARDURA is used concomitantly with strong CYP3A inhibitors .

What is the dosage for Diblocin mesylate?

The recommended dose of Diblocin for hypertension is 1-16 mg daily. The recommended dose for benign prostatic hyperplasia is 1-8 mg daily.

  • Low blood pressure warning: Diblocin can cause your blood pressure to become low. This may cause dizziness, lightheadedness, and vertigo when you stand up. This is most common with your first dose of medication, but it can also occur when your doctor changes your dosage. To help prevent this problem, your doctor will start you on the lowest dosage and slowly increase it.
  • Cataract surgery warning: Intraoperative floppy iris syndrome (IFIS) can occur during cataract surgery in people who take or have taken Diblocin. Be sure to tell your doctor if you have a cataract surgery planned.

Diblocin oral tablet is a prescription drug. It comes in immediate-release and extended-release forms.

Diblocin oral tablets are available as the brand-name drugs Cardura (immediate release) and Cardura XL (extended release). The immediate-release form is also available in a generic version. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

Diblocin dosing information

Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day. Maintenance dose: 1 to 16 mg orally once a day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: Immediate-release: 1 mg orally once a day. Extended-release: 4 mg orally once a day with breakfast

Maintenance dose: Immediate-release: 1 to 8 mg orally once a day. Extended-release: 4 to 8 mg orally once a day with breakfast. Depending on the patient's symptomatic response and tolerability, the dose may be increased to 8 mg (the maximum recommended dose). The recommended titration interval is 3 to 4 weeks.

If switching from immediate-release Diblocin tablets to extended-release tablets, therapy should be initiated with the lowest dose (4 mg once daily). Prior to starting therapy with Diblocin extended-release tablets, the final evening dose of immediate-release tablets should not be taken. If Diblocin extended-release tablets are discontinued for several days, therapy should be restarted using the 4 mg once daily dose.

Usual Geriatric Dose for Hypertension:

Initial dose: 0.5 mg orally once a day.

CONTRAINDICATIONS

The use of CARDURA is contraindicated in patients with a hypersensitivity to Diblocin, other quinazolines (e.g., prazosin, terazosin), or any of its components.


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