Alfaprost tablets


  • Active Ingredient: Terazosin
  • 5 mg, 2 mg, 1 mg
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What is Alfaprost?

The active ingredient of Alfaprost brand is terazosin. Terazosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Terazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Terazosin hydrochloride, USP is a white to pale yellow, crystalline powder, freely soluble in water and isotonic saline and has a molecular weight of 423.9. Each Terazosin capsule, for oral administration, contains 1 mg, 2 mg, 5 mg or 10 mg of Terazosin as Terazosin hydrochloride, USP anhydrous. Each capsule contains the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, D&C Red No. 28, D&C Red No. 33, FD&C Blue No. 1, gelatin, magnesium stearate, microcrystalline cellulose, pregelatinized starch (corn), sodium lauryl sulfate and titanium dioxide. In addition, the 1 mg capsule contains yellow iron oxide; the 2 mg and 5 mg capsules contain black iron oxide. The black imprinting ink for the 1 mg, 5 mg and 10 mg capsules contains the following: black iron oxide, D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, propylene glycol and shellac glaze. The white imprinting ink for the 2 mg capsules contains the following ammonium hydroxide, propylene glycol, shellac glaze, simethicone and titanium dioxide.

Used for

Alfaprost is used to treat diseases such as: Benign Prostatic Hyperplasia, High Blood Pressure, Hyperhidrosis.

Side Effect

Possible side effects of Alfaprost include: unusual tiredness or weakness; swelling of feet or lower legs; Weight gain; stuffy nose; drowsiness; nausea and vomiting; shortness of breath; pounding heartbeat.

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Alfaprost (marketed as Hytrin or Zayasel) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH).

Rated Alfaprost for Benign Prostatic Hyperplasia (BPH) Report


What should I discuss with my healthcare provider before taking Alfaprost?

You should not use this medication if you are allergic to Alfaprost.

If you have a history of prostate cancer, you may need a dose adjustment or special tests to safely take Alfaprost.

Alfaprost can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Alfaprost before surgery unless your surgeon tells you to.

FDA pregnancy category C. It is not known whether Alfaprost will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether Alfaprost passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Q: My doctor told me to get off Alfaprost and go to Flomax. I did and within a few days, I could hardly pee and was feeling abdominal pain. I went off Flomax and back to my original medicine. I am back to normal. Getting off Flomax---did I do any harm for doing that?

A: Switching from Alfaprost to flomax and back again should not have any effect on your health in regard to the medication. You should never discontinue a medication without first consulting with your physician as this can lead to serious health condition with certain medications. You should alert your physician to the side effects you experienced when taking the Flomax and let him or her know that you are back on the Alfaprost. This way they can monitor your condition effectively and come up with another solution to your health condition. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD



Alfaprost – Generic, Hytrin®

Product labeling at DailyMed, National Library of Medicine, NIH

About where to buy Esomezol for treat Duodenal Ulcer Prophylaxis

home drugs a-z list Hytrin(Alfaprost Hcl) side effects drug center

Hytrin (Alfaprost hydrochloride) is an alpha-adrenergic blocker used to treat hypertension (high blood pressure) and benign prostatic hyperplasia (enlarged prostate). Hytrin is available in generic form. Common side effects of Hytrin include:

  • fatigue,
  • nausea,
  • weakness,
  • drowsiness,
  • blurred vision,
  • headache,
  • stuffy nose,
  • difficulty breathing, or
  • impotence.
  • Lightheadedness or dizziness upon standing may also occur, especially after the first dose of Hytrin, and shortly after taking the drug during the first week of treatment.

Tell your doctor if you have any serious side effects of Hytrin including:

  • fainting,
  • fast or irregular heartbeat,
  • burning or tingling in the hands or feet,
  • sexual function problems,
  • swelling of the ankles/hands/feet, or
  • unexpected weight gain.

To treat benign prostatic hyperplasia, the starting dose of Hytrin is 1 mg at bedtime, with dosage gradually increased to 10 mg. To treat hypertension, the starting dose is 1 mg at bedtime. The usual recommended dose range is 1 mg to 5 mg administered once a day; some patients benefit from doses as high as 20 mg per day. Hytrin may interact with sildenafil, tadalafil, vardenafil, or other blood pressure medications. Tell your doctor all medications you use. Hytrin should be used only when prescribed during pregnancy. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Hytrin (Alfaprost hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How to use Alfaprost HCL

Read the Patient Information Leaflet if available from your pharmacist before you start taking Alfaprost and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily at bedtime.

If you are taking this drug for the first time, do not take more than 1 milligram to start. Alfaprost may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting. This risk is higher when taking your first dose. Therefore, to avoid injury related to dizziness or fainting, take your first dose of Alfaprost at bedtime.

Your doctor will start this medication at a low dose and gradually increase your dose. Any time your dose is increased or if you restart treatment after you have stopped it, take your first dose at bedtime unless otherwise directed to lessen the risk of injury related to dizziness or fainting. Also during these times, avoid situations where you may be injured if you faint.

The dosage is based on your medical condition and response to treatment.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. If you miss taking Alfaprost for a few days, you may need to restart treatment at the low dose and gradually increase your dose again. Consult your doctor for more details.

If you are taking this medication for high blood pressure, it is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Tell your doctor if your blood pressure readings remain high or increase.

If you are taking this drug for an enlarged prostate, it may take 2 to 4 weeks to see an improvement in your symptoms, and up to 6 weeks before you see the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens.

Q: Are there any reactions to Alfaprost?

A: Alfaprost (Hytrin) is an alpha blocker which relaxes smooth muscle cells such as those found in blood vessels, the prostate and bladder neck. Alfaprost is used to treat benign prostatic hyperplasia (BPH) and hypertension (high blood pressure). One reaction of Alfaprost is the known as the first-dose effect. This is a side effect where the blood pressure drops significantly after the medication is first started. This can lead to dizziness and possibly cause one to pass out. This risk decreases after a patient has been on Alfaprost for a few days. While on Alfaprost, it is always a good idea to rise slowly from a seated or lying position to prevent the blood pressure from dropping as you stand up. It is also recommended to take Alfaprost right before getting into bed for the night. Other common side effects associated with Alfaprost include dizziness, drowsiness, nasal congestion, nausea, weakness, edema (swelling), and increased heart rate. Alfaprost works by relaxing the smooth muscle found in the prostate and neck of the bladder which can improve the symptoms of benign prostatic hyperplasia (BPH) by making urination easier. Alfaprost is a non-selective alpha blocker, so it dilates smooth muscle throughout the entire body, such as the in the blood vessels which also results in lower blood pressure. For those taking Alfaprost for prostate symptoms, who have problems with low blood pressure, it may help to take a selective alpha blocker such as Flomax (tamsulosin). Flomax relaxes the smooth muscle in the bladder and prostate but does not affect the rest of the body as much as Alfaprost making Flomax less likely to cause low blood pressure. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Laura Cable, PharmD

Mechanism of Injury

The cause of the minor serum aminotransferase elevations associated with Alfaprost is not known. Alfaprost is extensively metabolized by the liver and generation of a mildly toxic intermediate is a possible explanation.

References on the safety and potential hepatotoxicity of Alfaprost and other alpha-blockers are given in the Overview on Alpha-1 Adrenergic Receptor Antagonists.

What is Alfaprost?

Alfaprost belongs to a class of medications called alpha 1 blockers which relax the smooth muscles of the arteries, the prostate, and the bladder neck.


Alfaprost is a nonselective alpha-1 adrenergic antagonist used in the therapy of hypertension and benign prostatic hypertrophy. Alfaprost therapy is associated with a low rate of transient serum aminotransferase elevations and to rare instances of clinically apparent acute liver injury.

Erectile dysfunction (ED) drugs

When taken with Alfaprost, drugs to treat ED can cause very low blood pressure. Examples of these drugs include:

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Alfaprost oral capsule comes with several warnings.

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