The active ingredient of Zyllt brand is clopidogrel. Clopidogrel helps to prevent platelets in your blood from sticking together and forming a blood clot. Unwanted blood clots can occur with certain heart or blood vessel conditions. Pharmacodynamic and pharmacokinetic parameters measured in these studies showed that the interaction was highest with omeprazole and least with dexlansoprazole. Effect of Clopidogrel on other drugs In vitro studies have shown that the glucuronide metabolite of Clopidogrel is a strong inhibitor of CYP2C8. Concomitant administration of repaglinide with Clopidogrel increased the systemic exposure to repaglinide (AUC0-∞) by 5.1-fold following the loading dose (300 mg) and by 3.9-fold on day 3 of the maintenance dose (75 mg) of Clopidogrel [see Drug Interactions (7.5)].
Zyllt is used to treat diseases such as: Acute Coronary Syndrome, Acute Coronary Syndrome, Prophylaxis, Heart Attack, Ischemic Stroke, Ischemic Stroke, Prophylaxis, Percutaneous Coronary Intervention, Peripheral Arterial Disease, Platelet Aggregation Inhibition, Transient Ischemic Attack.
Possible side effects of Zyllt include: dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position; bloating; unusual tiredness or weakness; sweating; headache (sudden, severe); change in mental status; loss of appetite.
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|Click on citations within drug and disease topics in our clinical reference to review the clinical evidence on MEDLINE.||155$|
|It is given to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems that could cause a stroke or heart attack.||145$|
|You may be able to lower your total cost by filling a greater quantity at one time.||140$|
|The FDA extended the patent protection of clopidogrel by six months, giving exclusivity that would expire on May 17, 2012.||178.87$|
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|Get Started My Medicine Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.||139.78$|
|CYP2C19 metabolizer groups, evaluated pharmacokinetic and antiplatelet responses using 300 mg followed by 75 mg per day and 600 mg followed by 150 mg per day, each for a total of 5 days.||46$|