Is Zela safe to take if I'm pregnant or breastfeeding?
There are no adequate clinical trials of Zela administration during pregnancy. Zela should only be used during pregnancy if the potential benefit of treatment justifies the potential risk to the fetus. Zela has been classified FDA as pregnancy risk category C.
It is not known if Zela is excreted in human milk. Due to the lack of safety data, Zela should be used cautiously during breastfeeding.
Studies in children younger than 6 years are limited, but several studies have shown Zela to be safe in children as young as 1 year of age. For children 1–2 years old, a dose of 200 mg is recommended. Use of Zela in children
In the fed state, praziquantel (40 mg/kg) increased mean maximum plasma concentration and area under the curve of Zela sulfox >
What are the side effects of Zela?
Side effects which occurred with a frequency of
What Are Side Effects Associated with Using Zela?
Common side effects of Zela include:
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
What other drugs will affect Zela?
Other drugs may interact with Zela, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Zela is used for managing different worm infections. It removes the earthworms of the nutrients called for to multiply and endure, consequently killing them in the body. Zela is suggested for 2 weeks or as a solitary dosage. It may have to be taken when or two times a day, relying on the level of invasion and sort of infection treated. Aftering specific instructions is always vital for the person to effectively overcome the infection.
Mechanism of Action
ALBENZA binds to the colchicine-sensitive site of β-tubulin inhibiting their polymerization into microtubules. The decrease in microtubules in the intestinal cells of the parasites decreases their absorptive function, especially the uptake of glucose by the adult and larval forms of the parasites, and also depletes glycogen storage. Insufficient glucose results in insufficient energy for the production of adenosine trisphosphate (ATP) and the parasite eventually dies.
Mechanism of Resistance
Parasitic resistance to Zela is caused by changes in amino acids that result in changes in the β-tubulin protein. This causes reduced binding of the drug to β-tubulin.
In the specified treatment indications Zela appears to be active against the larval forms of the following organisms:
Zela Tablets 400 Mg Price In India
It could have to be taken once a day, depending upon the level of infestation and kind of infection addressed. It may be prescribed for infections that include the existence of pinworms, hookworms, whipworms, usual roundworms or tapeworms. You can constantly pick a relied on drug store on our secure contrast web page and make certain ahead back there looking for large amounts and very high quality, taking best care of yours health.
Adverse reactions and s > Leukopenia and thrombocytopenia are possible in dogs and cats. Zela has an affinity for rapidly dividing cells and may cause toxicity to bone marrow and intestinal epithelium. High doses have been associated with bone marrow toxicity ( J Am Vet Med Assoc, 213: 44-46, 1998) in dogs and cats, and it should be used cautiously in small animals. In other species, at approved doses, there is a wide margin of safety. Adverse effects can include anorexia, lethargy, and bone marrow toxicity.
Steady-state trough concentrations of Zela sulfoxide were about 56% higher when 8 mg dexamethasone was co-administered with each dose of Zela (15 mg/kg/day) in 8 neurocysticercosis patients.
About Zela 400 MG Tablet
Zela is an antiparasitic medication which treats diseases caused by an infestation of parasitic worms. It is generally taken for diseases like neurocysticercosis (affecting the brain, muscles and other tissues), giardiasis (intestinal infection), hydatid disease, pinworm disease (intestinal infection), ascariasis (gastrointestinal infection), filariasis (affecting the lymph nodes and vessels) and others. The medicine falls under the group of drugs known as anthelmintics, which expels the parasitic worms either by stunning them or killing them without causing notable damage to the host body. It is available in the form of tablets and taken.
Before you start this medication, you must inform your doctor if you have any of the following health conditions:
- Blockage in the biliary tract
- Liver disease
- A low blood count (low platelet, white cell or red cell count)
- If you are pregnant or planning to get pregnant
- If you are a breast-feeding mother
- In case you are allergic to Zela 400 MG Tablet, or any other medicines or food
In case you forget to take a dose of this medication, you can take it as soon as you remember it. Do not take two doses together just because you missed one. It should also be kept in mind not to stop your medicines before the prescribed time, even if you think you are feeling better. Apart from that, you must consult your child’s paediatrician before using this tablet to treat your child’s condition.
Zela is a benzimidazole and anthelmintic agent most commonly used in the treatment of echinococcosis (also known as Hydatid cysts) and neurocysticercosis . It causes degenerative alterations to the tegument and intestine of worms; this leads to impaired uptake of glucose and causes a depletion of glycogen stores . Zela ultimately causes a decrease in the production of ATP which causes immobilization and death of the worm.