Nacor tablets

Nacor

  • Active Ingredient: Enalapril
  • 10 mg, 5 mg
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What is Nacor?

The active ingredient of Nacor brand is enalapril. Enalapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. C20H28N2O5в€™C4H4O4 M.W. 492.53 Enalapril maleate, USP is an off-white, crystalline powder. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol. Enalapril is a pro-drug; following oral administration, it is bioactivated by hydrolysis of the ethyl ester to enalaprilat, which is the active angiotensin converting enzyme inhibitor. Enalapril maleate tablets USP are supplied as 2.5 mg, 5 mg, 10 mg, and 20 mg tablets for oral administration. In addition, each tablet contains the following inactive ingredients: corn starch, lactose monohydrate, magnesium stearate, pregelatinized starch, and sodium bicarbonate. Each 2.5 mg tablet contains D&C red #27 aluminum lake, D&C yellow #10 aluminum lake, FD&C blue #1 aluminum lake, FD&C red #40 aluminum lake, and FD&C yellow #6 aluminum lake. Each 10 mg tablet contains FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake and FD&C yellow #6 aluminum lake. Each 20 mg tablet contains FD&C Yellow #6.

Used for

Nacor is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, Heart Failure, High Blood Pressure, Hypertensive Emergency, Left Ventricular Dysfunction.

Side Effect

Possible side effects of Nacor include: confusion; sweating; rash; Lack or loss of strength; Dizziness; fever or chills; sneezing; sore throat.

How to Buy Nacor tablets online?

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What should I avoid while taking Nacor?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of Nacor.

Do not use salt substitutes or potassium supplements while taking Nacor, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

More common side effects

The more common side effects that can occur with Nacor include:

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Dosages of Nacor:

Powder for oral solution (Epaned)

  • 150 mg bottle (1mg/mL after reconstitution)

What Other Drugs Interact with Nacor?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Severe Interactions of Nacor include:

Nacor has serious interactions with at least 38 different drugs.

Nacor has moderate interactions with at least 110 different drugs.

Nacor has mild interactions with at least 31 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

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Nacor Warnings

One of the side effects of Nacor is dizziness, so don’t drive if it makes you dizzy.

Nacor can also worsen kidney problems in people who already have kidney disease.

Discuss your medical history with your doctor to determine if you are allergic to Nacor, or other ACE inhibitors. Inactive ingredients can cause allergic reactions.

4. How and when to take it

It's usual to take Nacor once or twice a day.

Your doctor may advise you to take your first dose before bedtime, because it can make you dizzy. After the first dose, if you do not feel dizzy, you can take Nacor at any time of day. Try to take it at the same time every day.

If you have Nacor twice a day, try to take it once in the morning and once in the evening. Leave 10 to 12 hours between doses if you can.

Serious side effects

Some people have serious side effects after taking Nacor.

Call a doctor straight away if you get:

  • yellow skin or the whites of your eyes turn yellow - this could be a sign of liver problems
  • paleness, feeling tired, faint or dizzy, any sign of bleeding (like bleeding from the gums or bruising more easily), sore throat and fever and getting infections more easily - these could be signs of a blood or bone marrow disorder
  • a faster or irregular heart rate, chest pain and tightness in your chest - these could be signs of heart problems
  • shortness of breath, wheezing and tightening of the chest - these could be signs of lung problems
  • severe stomach pain that could reach through to your back - this could be a sign of an inflamed pancreas (pancreatitis)
  • swollen ankles, blood in your pee or not peeing at all - these could be signs of kidney problems
  • weak arms and legs or problems speaking - it's important to check these out in case they are signs of a stroke

If you suspect that you or someone else is having a stroke, phone 999 immediately and ask for an ambulance.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Nacor only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 11.03.

A multiple dose pharmacokinetic study was conducted in 40 hypertensive male and female pediatric patients aged 2 months to ≤ 16 years following daily oral administration of 0.07 to 0.14 mg/kg Nacor maleate. At steady state, the mean effective half-life for accumulation of Nacorat was 14 hours, and the mean urinary recovery of total Nacor and Nacorat in 24 hours was 68% of the administered dose. Conversion of Nacor to Nacorat was in the range of 63-76%. The overall results of this study indicate that the pharmacokinetics of Nacor in hypertensive children aged 2 months to ≤ 16 years are consistent across the studied age groups and consistent with pharmacokinetic historic data in healthy adults.

In a clinical study involving 110 hypertensive pediatric patients 6 to 16 years of age, patients who weighed

Before taking this medicine

You should not use Nacor if you are allergic to it, or if you have:

you have a history of angioedema;

you recently took a heart medicine called sacubatril; or

if you are allergic to any other ACE inhibitor, such as benazepril, captopril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

Do not take Nacor within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).

If you have diabetes, do not use Nacor together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

You may also need to avoid taking Nacor with aliskiren if you have kidney disease.

To make sure Nacor is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis);

a history of blood clot or stroke (including TIA or "mini-stroke");

an electrolyte imbalance (such as high levels of potassium in your blood); or

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Nacor can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Nacor can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Q: About two weeks ago, while undergoing tests for allergies, I had an allergic reaction; swelling in my lips. I usually take Nacor 20 mg. It didn't seem to work to help lower my blood pressure, which rose to 183/121. Since then I've been careful to avoid anything with any type of nuts since the reaction was caused by almonds. However, yesterday, under my lower lip, I noticed a funny feeling and I eventually looked in the mirror. I saw redness and one small spot of swelling on the skin. I was baffled as to what could have caused it. I later remember it hadn't been long since I'd taken a dose of Nacor. Could this be angioedema? I have never had problems like this with Nacor and I've been taking it for at least five years. I do feel I have plateaued on it. I've been taking the maximum dose for more than a year and it doesn't seem to have the same effects as before. I can only take ACE inhibitors and ARBs to lower my blood pressure because of other medical conditions, including CHF. Should I switch to another ACE inhibitor? My blood pressure is around 140/90 when I take Nacor only, and I was supposed to have a second medication, but which one should I take? I've had trouble with some of the others including clonidine, nifedipine, Norvasc, metoprolol and propanolol, and they all had to be stopped.

A: Angioedema is an uncommon side effect associated with Nacor and usually occurs in the first month of treatment. Although it is possible to experience this condition later during treatment, it is more common in African American patients, women, and people who have a history of drug or seasonal allergies. The exact prevalence and incidence of ARB-induced angioedema are not known, but it is thought to be significantly lower than the ACE inhibitors. For patients who cannot take any other alternatives, ARBs seem to be the way to go for people who have had this issue with ACE inhibitors, although careful monitoring is recommended for the physician. There are no clear cut ways to distinguish which medication would be best in this case for your condition, but it has been shown that losartan (Cozaar) seems to show the most cases with angioedema, if it happens at all, with the ARBs. Lori Poulin, PharmD

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to Nacor. Your doctor may order certain lab tests to check your body's response to Nacor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Angioedema

Angioedema, including laryngeal edema, may occur at any time during treatment with angiotensin converting enzyme inhibitors, including Nacor. Patients should be so advised and told to report immediately any signs or symptoms suggesting angioedema (swelling of face, extremities, eyes, lips, tongue, difficulty in swallowing or breathing) and to take no more drug until they have consulted with the prescribing physician.

Before taking Nacor

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking Nacor it is important that your doctor knows:

  • If you are pregnant or breastfeeding.
  • If you have any problems with the way your k >

Nacor S >

Less serious side effects of Nacor include:

  • Nausea, diarrhea
  • Dizziness, headache, drowsiness
  • Dry mouth
  • Coughing
  • Loss of appetite, ability to taste
  • Insomnia
  • Rash, itching

More serious side effects may demand immediate emergency medical attention and include:

  • Fainting, feeling lightheaded
  • Fever, flu symptoms, body aches
  • Urinating more or less than usual
  • Fast heartbeats
  • Chest pain
  • Rap >Back to Top

Why it's used

Nacor oral tablet is used to treat high blood pressure, heart failure, and asymptomatic left ventricular dysfunction.

Nacor may be used as part of a combination therapy. That means you need to take it with other drugs.

Innovace, Innoz >About Nacor
  • Before taking Nacor
  • How to take Nacor
  • Getting the most from your treatment
  • Can Nacor cause problems?
  • How to store Nacor
  • Important information about all medicines

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