ALBENZA (Mebel) is an orally administered anthelmintic drug. Chemically, it is methyl 5-(propylthio)-2-benzim >12 H 15 N 3 O 2 S. Its molecular weight is 265.34. It has the following chemical structure:
What are the side effects of Mebel?
Side effects which occurred with a frequency of
Mebel is pregnancy category C. Data on the use of Mebel in pregnant women are limited, though the available evidence suggests no difference in congenital abnormalities in the children of women who were accidentally treated with Mebel during mass prevention campaigns compared with those who were not. In mass prevention campaigns for which the World Health Organization (WHO) has determined that the benefit of treatment outweighs the risk, WHO allows use of Mebel in the 2nd and 3rd trimesters of pregnancy. However, the risk of treatment in pregnant women who are known to have an infection needs to be balanced with the risk of disease progression in the absence of treatment.
Pregnancy Category C: Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal, or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.
It is not known whether Mebel is excreted in human milk. Mebel should be used with caution in breastfeeding women.
The safety of Mebel in children less than 6 years old is not certain. Studies of the use of Mebel in children as young as one year old suggest that its use is safe. According to WHO guidelines for mass prevention campaigns, Mebel can be used in children as young as 1 year old. Many children less than 6 years old have been treated in these campaigns with Mebel, albeit at a reduced dose.
Trichinosis Worm Infection
Trichinosis is a food-borne disease caused by ingesting parasites (roundworms) in undercooked pork or wild-game meat. Symptoms of trichinosis include diarrhea, nausea, muscle aches, itching, fever, chills, and joint pains.Trichinosis usually resolves without treatment, but more severe cases are treated with thiabendazole (Mintezol), Mebel (Abenza), or mebendazole (Vermox).