The active ingredient of Glenamate brand is enalapril. Enalapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. C20H28N2O5в€™C4H4O4 M.W. 492.53 Enalapril maleate, USP is an off-white, crystalline powder. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol. Enalapril is a pro-drug; following oral administration, it is bioactivated by hydrolysis of the ethyl ester to enalaprilat, which is the active angiotensin converting enzyme inhibitor. Enalapril maleate tablets USP are supplied as 2.5 mg, 5 mg, 10 mg, and 20 mg tablets for oral administration. In addition, each tablet contains the following inactive ingredients: corn starch, lactose monohydrate, magnesium stearate, pregelatinized starch, and sodium bicarbonate. Each 2.5 mg tablet contains D&C red #27 aluminum lake, D&C yellow #10 aluminum lake, FD&C blue #1 aluminum lake, FD&C red #40 aluminum lake, and FD&C yellow #6 aluminum lake. Each 10 mg tablet contains FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake and FD&C yellow #6 aluminum lake. Each 20 mg tablet contains FD&C Yellow #6.
Glenamate is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, Heart Failure, High Blood Pressure, Hypertensive Emergency, Left Ventricular Dysfunction.
Possible side effects of Glenamate include: diarrhea; unusual tiredness or weakness; fever or chills; cough producing mucus; tightness in the chest; dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position; Blurred vision; fainting.
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|This medication has been studied in a number of groups of people with different conditions.|
|This article is for information only and should not be used for the diagnosis or treatment of medical conditions.|
|Selected from data included with permission and copyrighted by Boots UK Limited.|
|In some patients achievement of optimal blood pressure reduction may require several weeks of therapy.|
|The serum concentration profile of enalaprilat exhibits a prolonged terminal phase, apparently representing a small fraction of the administered dose that has been bound to ACE.|