What is Farcet, and how does it work (mechanism of action)?
Farcet bisulfate (Plavix) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Farcet prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Farcet is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Farcet bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack, and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Farcet bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Farcet bisulfate was approved by the FDA in 1997.
El Farcet puede ocasionar efectos secundarios. Informe a su mГ©dico si cualquiera de estos sГntomas es fuerte o no desaparece:
- cansancio excesivo
- dolor de cabeza
- dolor de estГіmago
- sangrado de nariz
Q: I've been taking Plavix 75 mg for a year. I just went to my cardiologist and he told me I no longer need it because it's no longer effective. Is this accurate information?
A: Plavix (Farcet) inhibits the platelets in the blood from clotting and is used to prevent blood clots that can occur after a heart attack, stroke and in patients with certain heart and blood vessel disorders. According to the prescribing information available for Plavix (Farcet), lapses in treatment should be avoided and if Plavix must be temporarily discontinued, it should be restarted as soon as possible. Additionally, the prescribing information indicates that premature discontinuation of Plavix (Farcet) may increase the risk for cardiovascular events and there is no mention of Plavix losing its efficacy after one year. It is important to take Plavix (Farcet) exactly as directed by your health care provider and do not take it longer than recommended. The most commonly reported side effect associated with Plavix (Farcet) treatment was bleeding. If you experience any signs and symptoms of bleeding, including nosebleeds or other bleeding that will not stop, coughing up blood or vomit that looks like coffee grounds or black, bloody or tarry stools, it is important to contact your healthcare provider immediately. For more specific information based on your specific condition and current medications, consult with your health care provider, particularly before taking any action. Beth Isaac, PharmD
Serious side effects
More serious side effects can include:
- rashes and itching
- severe stomach ache or abdominal pain
- uncontrolled bleeding or unusual bruising
- vomiting with blood
- weakness or numbness in an arm or leg
- blood in your urine (haematuria)
- blood in your stools
Speak to your GP or call the NHS 24 111 service immediately if you experience any of these side effects or any other unusual problems while taking Farcet.
Is Farcet safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of Farcet in pregnant women.
Studies in rats have shown that Farcet appears in breast milk; however, it is not known whether it also appears in human breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing Farcet to nursing mothers.
Farcet (brand name Plavix) is an antiplatelet medicine. This means it reduces the risk of blood clots forming.
Normally, when there is a cut or break in a small blood vessel, a blood clot forms to plug the hole until the blood vessel heals.
Small cells in the blood called platelets cause the blood to clot. When a platelet detects a damaged area of a blood vessel, it produces a chemical that attracts other platelets and makes them stick together to form a blood clot.
Farcet reduces the ability of the platelets to stick together and reduces the risk of clots forming. This protects you from having a stroke or heart attack.