Corel tablets


  • Active Ingredient: Carvedilol
  • 25 mg, 12.5 mg, 6.25 mg
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What is Corel?

The active ingredient of Corel brand is carvedilol. Carvedilol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). C24H26N2O4 M.W. 406.47 Carvedilol tablets USP are white, elliptical-shaped, film-coated tablets containing 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg of Carvedilol, USP. Inactive ingredients consist of colloidal silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, polyethylene glycol, polysorbate, povidone, and titanium dioxide. Carvedilol, USP is a white or nearly white, crystalline powder. Slightly soluble in alcohol; practically insoluble in water and in dilute acids. Carvedilol tablets USP meet USP Dissolution Test 2.

Used for

Corel is used to treat diseases such as: Angina, Atrial Fibrillation, Heart Failure, High Blood Pressure, Left Ventricular Dysfunction.

Side Effect

Possible side effects of Corel include: weight gain; chills; dizziness, lightheadedness, or fainting; swollen or painful glands; prickling or tingling sensation; flushed, dry skin; loss of strength or energy; decreased tearing.

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OTHER NAME(S): Corel Tablet

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks.

When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat.

Corel is used to treat high blood pressure and heart failure. It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Corel belongs to a class of drugs known as alpha and beta blockers.

home drugs a-z list Coreg(Corel) side effects drug center

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Coreg (Corel) is a beta-adrenergic blocking agent (beta-blocker) used to treat heart failure, hypertension, and left ventricular dysfunction after a heart attack. Coreg is available in generic form. Common side effects of Coreg include

Contact your doctor if you experience serious side effects of Coreg including

  • feeling faint,
  • slow or irregular heart beats,
  • chest pain,
  • shortness of breath,
  • difficulty swallowing
  • loss of bladder control, or
  • severe skin reaction.

Coreg is available in strengths of 3.125, 6.25, 12.5, or 25 mg tablets. Coreg is usually taken with food; the recommended starting dose of Coreg (Corel) is 3.125 mg twice daily for 2 weeks for heart failure while for other problems, the starting dose is 6.25 mg twice a day. Coreg may have serious side effects that include hypotension, chest pain, irregular heartbeat, difficult breathing and swallowing, hives or rash, swelling, and fainting. Patients with hepatic impairment should not take Coreg. Coreg may interact with allergy treatments (or if you are undergoing allergy skin-testing), cimetidine, cyclosporine, fluconazole, insulin or oral diabetes medications, rifampin, antidepressants, heart or blood pressure medicines, heart rhythm medications, HIV or AIDS medicines, MAO inhibitors, medicine to prevent or treat nausea and vomiting, medicine to treat psychiatric disorders, or narcotics. Tell your doctor all medications and supplements you use. Severe exacerbation of angina, heart attack and ventricular arrhythmias has been reported in angina patients following the abrupt discontinuation of therapy with beta-blockers like Coreg. Effectiveness of COREG (Corel) in patients younger than 18 years of age has not been established. There are no adequate and well-controlled studies in pregnant or breastfeeding women; Coreg may be used during pregnancy or breastfeeding only if the potential benefit justifies the potential risk to the fetus or infant.

Our Coreg Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings for other groups

For pregnant women: Corel is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Tell your doctor if you’re pregnant or plan to become pregnant. Corel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

For women who are breastfeeding: It isn’t known if Corel passes into breast milk. If it does, it may cause serious effects in a breastfeeding child. You and your doctor may need to decide if you’ll take Corel or breastfeed.

For seniors: Seniors may be more likely to experience dizziness while taking this drug.

For children: It has not been established that Corel is safe and effective for use in people under the age of 18 years.

Rated Corel for Hypertension Report

Absolutely terrible. I've never felt this bad in my entire life.Zero energy have no life now,can't focus,mind is always foggy,pains everywhere on my body.Can't take this much longer,i'm at my wits end.


Corel (Coreg, Coreg CR) drug prescribed to control high blood pressure in addition to a diuretic. Corel also may be prescribed in addition with other drugs to manage mild to moderate congestive heart failure and heart disease for patients who have suffered a recent heart attack. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication.

Can Corel cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Corel. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.


Corel is an oral medication used in a twice a day dosing therapy in immediate-release form or daily dosing in a controlled release form. The dose is individualized based on blood pressure and heart rate response, although if used in heart failure, the dose gets titrated up as directed by guideline-directed management and therapy. Dose ranges include from 3.125 mg twice daily to 25 mg twice daily. A total dose of up to 100 mg daily is permissible in patients weighing over 85 kg. Per guideline-directed management and therapy for heart failure, Corel is up-titrated to 25 mg twice daily as tolerated.

Serious Side Effects of Corel

  • Low or uneven heartbeats
  • Swelling
  • Rapid weight gain
  • Loss of bladder control
  • Chest pain
  • Wheezing
  • Chest tightness
  • Trouble breathing

If you experience any of these problems, call your doctor right away.

Other conditions that require you to reach out to your physician include:

  • Shortness of breath for no apparent reason
  • Numbness or a cold feeling in your hands and feet
  • Pale skin
  • Lightheadedness
  • Rapid heart beat
  • Trouble concentrating
  • Severe skin reaction
  • Fever
  • Sore throat
  • Burning eyes
  • Increased thirst
  • Urination
  • Hunger
  • Dry mouth
  • Fruity breath odor
  • Drowsiness
  • Dry skin
  • Blurred vision
  • Weight loss
  • Skin pain (followed by a red or purple skin rash that spreads, especially on the face or upper body, and causes blistering and peeling)

Seek emergency medical care immediately if you think you are having an allergic reaction.

Signs may range from swelling of your face, lips, tongue, or throat to hives and difficulty breathing.

Is Corel safe to take if I'm pregnant or breastfeeding?

  • Safe use of Corel during pregnancy has not been established.
  • No studies with Corel are available in nursing mothers; however, use is not recommended due to the risk of a slow heart rate in the infant.

Rated Corel for Hypertension Report

Caused abdominal pain & diarrhea. Blood pressure increased instead of decreasing.

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