Corafen tablets

Corafen

  • Active Ingredient: Carvedilol
  • 25 mg, 12.5 mg, 6.25 mg
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What is Corafen?

The active ingredient of Corafen brand is carvedilol. Carvedilol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). C24H26N2O4 M.W. 406.47 Carvedilol tablets USP are white, elliptical-shaped, film-coated tablets containing 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg of Carvedilol, USP. Inactive ingredients consist of colloidal silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, polyethylene glycol, polysorbate, povidone, and titanium dioxide. Carvedilol, USP is a white or nearly white, crystalline powder. Slightly soluble in alcohol; practically insoluble in water and in dilute acids. Carvedilol tablets USP meet USP Dissolution Test 2.

Used for

Corafen is used to treat diseases such as: Angina, Atrial Fibrillation, Heart Failure, High Blood Pressure, Left Ventricular Dysfunction.

Side Effect

Possible side effects of Corafen include: blood in the urine; dark urine; convulsions; stomachache; dizziness, faintness, or lightheadedness when getting up suddenly from a lying position; depression; nervousness.

How to Buy Corafen tablets online?

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Rated Corafen for Hypertension Report

I took this drug for several years at the lowest dosage. Then my BP went up and they increased my dosage, a few months later my BP rose again and they increased the dosage again. At that point I began to have chest pain and labored breathing with out of control BP. I ended up in ER. They reduced my BP and upped the medicine again and checked my heart with all manner of tests, all came back fine. Chest pain continued and became so dizzy I couldn't walk, passed out a couple of times. They took me off the Correg and it took about 2 weeks to get back to normal. My PB is going back up but not taking Correg.

Corafen may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • tiredness
  • weakness
  • lightheadedness
  • dizziness
  • headache
  • diarrhea
  • nausea
  • vomiting
  • vision changes
  • joint pain
  • difficulty falling asleep or staying asleep
  • cough
  • dry eyes
  • numbness, burning, or tingling in the arms or legs

Which drugs or supplements interact with Corafen?

Corafen can mask early warning symptoms of low blood sugar (hypoglycemia) such as tremors and increased heart rate. (These symptoms are caused by activation of the adrenergic nervous system that are blocked by the Corafen.) Therefore, patients with diabetes taking medications that lower blood sugar such as insulin or oral anti-diabetic medications may need to monitor their blood sugar more often.

Corafen taken with calcium channel blockers (CCBs) such as diltiazem (Cardizem) or verapamil (Calan) may trigger an irregular heart rhythm or an increase in blood pressure.

Reserpine, monoamine oxidase inhibitors (phenelzine or isocarboxazid) and clonidine (Catapres), because they have similar mechanisms of action as Corafen, may greatly accentuate the effects of Corafen and cause a steep decline in blood pressure and/or heart rate. Close monitoring of blood pressure and heart rate may be needed.

Corafen may cause an increase in digoxin (Lanoxin) blood levels. Therefore, in patients receiving digoxin, the digoxin blood level should be monitored if Corafen is started, adjusted, or discontinued.

Rifampin (Rifadin) can sharply decrease the Corafen blood level. Therefore, in patients taking rifampin, the dose of Corafen may need to be increased.

Corafen shares a common pathway for elimination by the liver with several other drugs such as quinidine (Quinaglute), fluoxetine (Prozac), paroxetine (Paxil), or propafenone (Rythmol). Use of these drugs may block the elimination of Corafen. No studies have been done to confirm these effects on the elimination of Corafen; however, Corafen blood levels may be increased (along with the risk for Corafen's side effects) if patients are taking any of these drugs.

Corafen may increase cyclosporin (Sandimmune, Neoral) blood levels. The dose of cyclosporin may need to be adjusted when the two drugs are used together.

Amiodarone (Cordarone) may increase Corafen levels in the blood, increasing the effects and potential for toxicity of Corafen.

What is Corafen?

Corafen is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Corafen is used to treat heart failure and hypertension (high blood pressure). It is also used after a heart attack that has caused your heart not to pump as well.

Corafen may also be used for purposes not listed in this medication guide.


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