Serious Side Effects of Carviloc
- Low or uneven heartbeats
- Rapid weight gain
- Loss of bladder control
- Chest pain
- Chest tightness
- Trouble breathing
If you experience any of these problems, call your doctor right away.
Other conditions that require you to reach out to your physician include:
- Shortness of breath for no apparent reason
- Numbness or a cold feeling in your hands and feet
- Pale skin
- Rapid heart beat
- Trouble concentrating
- Severe skin reaction
- Sore throat
- Burning eyes
- Increased thirst
- Dry mouth
- Fruity breath odor
- Dry skin
- Blurred vision
- Weight loss
- Skin pain (followed by a red or purple skin rash that spreads, especially on the face or upper body, and causes blistering and peeling)
Seek emergency medical care immediately if you think you are having an allergic reaction.
Signs may range from swelling of your face, lips, tongue, or throat to hives and difficulty breathing.
Algunos efectos secundarios pueden ser graves. Si usted experimenta alguno de los siguientes sГntomas, llame a su doctor de inmediato:
- respiraciГіn entrecortada
- aumento de peso
- inflamaciГіn de los brazos, manos, pies, tobillos o pantorrillas
- dolor en el pecho
- ritmo cardГaco mГЎs lento que lo normal o irregular
- sarpullido (erupciones en la piel)
- dificultad para respirar o tragar
El Carviloc puede causar otros efectos secundarios. Llame a su doctor si tiene cualquier problema extraГ±o mientras toma este medicamento.
Si desarrolla un efecto secundario grave, usted o su doctor puede enviar un informe al programa de divulgaciГіn de efectos adversos 'MedWatch' de la AdministraciГіn de Alimentos y Medicamentos (FDA, por su sigla en inglГ©s) en la pГЎgina de Internet (http://www.fda.gov/Safety/MedWatch) o por telГ©fono al 1-800-332-1088.
COREG has been evaluated for safety in heart failure in more than 4,500 subjects worldw >
Table 1 shows adverse events reported in subjects with mild-to-moderate heart failure enrolled in U.S. placebo-controlled clinical trials, and with severe heart failure enrolled in the COPERNICUS trial. Shown are adverse events that occurred more frequently in drug-treated subjects than placebo-treated subjects with an incidence of greater than 3% in subjects treated with Carviloc regardless of causality. Median trial medication exposure was 6.3 months for both Carviloc and placebo subjects in the trials of mild-to-moderate heart failure and 10.4 months in the trial of subjects with severe heart failure. The adverse event profile of COREG observed in the long-term COMET trial was generally similar to that observed in the U.S. Heart Failure Trials.
Table 1. Adverse Events (%) Occurring More Frequently with COREG than with Placebo in Subjects with Mild-to-Moderate Heart Failure (HF) Enrolled in U.S. Heart Failure Trials or in Subjects with Severe Heart Failure in the COPERNICUS Trial (Incidence >3% in Subjects Treated with Carviloc, Regardless of Causality)
Cardiac failure and dyspnea were also reported in these trials, but the rates were equal or greater in subjects who received placebo.
The following adverse events were reported with a frequency of greater than 1% but less than or equal to 3% and more frequently with COREG in either the U.S. placebo-controlled trials in subjects with mild-to-moderate heart failure or in subjects with severe heart failure in the COPERNICUS trial.
Using Carviloc with certain diabetes drugs can make these diabetes drugs lower your blood sugar levels further. If you take these diabetes drugs with Carviloc, you’ll need to check your blood sugar regularly. Examples of these drugs include:
Rated Carviloc for Hypertension Report
I took 12.5 mg. twice a day. After a few days, I was SO tired, i could barely get going. It did not lower my blood pressure at all. My doctor said I just had to get used to it -- I don't think so. New meds or new doctor -- I am calling in the AM
Warnings for other groups
For pregnant women: Carviloc is a category C pregnancy drug. That means two things:
- Research in animals has shown adverse effects to the fetus when the mother takes the drug.
- There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.
Tell your doctor if you’re pregnant or plan to become pregnant. Carviloc should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
For women who are breastfeeding: It isn’t known if Carviloc passes into breast milk. If it does, it may cause serious effects in a breastfeeding child. You and your doctor may need to decide if you’ll take Carviloc or breastfeed.
For seniors: Seniors may be more likely to experience dizziness while taking this drug.
For children: It has not been established that Carviloc is safe and effective for use in people under the age of 18 years.
Carviloc shouldn’t be used with another beta-blocker. This combination may lower your heart rate and blood pressure too much. Examples of other beta-blockers include:
What is Carviloc? How does it work (mechanism of action)?
Carviloc is used for treating high blood pressure and congestive heart failure. It is related to labetalol (Normodyne, Trandate). Carviloc blocks receptors of the adrenergic nervous system, the system of nerves in which adrenalin (epinephrine) is active. Nerves from the adrenergic system enter the heart and release an adrenergic chemical (norepinephrine) that attaches to receptors on the heart's muscle and stimulates the muscle to beat more rapidly and forcefully. By blocking the receptors, Carviloc reduces the heart's rate and force of contraction and thereby reduces the work of the heart. Carviloc also blocks adrenergic receptors on arteries and causes the arteries to relax and the blood pressure to fall. The drop in blood pressure further reduces the work of the heart since it is easier to pump blood against a lower pressure.
The FDA first approved Carviloc in 1995.
History of serious hypersensitivity reaction (eg, Stevens-Johnson syndrome, anaphylactic reaction, angioedema) to any component of this medication or other medications containing Carviloc
Bronchial asthma, bronchospasm
Chronic obstructive pulmonary disease (COPD)
2°/3° AV block, sick sinus syndrome without permanent pacemaker, cardiogenic shock, severe bradycardia, decompensated heart failure requiring IV inotropic medication
Severe hepatic impairment
Alcohol interaction warning
Talk to your doctor before using alcohol while taking this medication. If you drink alcohol while taking Carviloc, your blood pressure may decrease to levels that are lower than normal. This can be dangerous.
Use cautioin in anesthesia or surgery (myocardial depression), cerebrovascular insufficiency, diabetes mellitus, hyperthyroidism or thyrotoxicosis, liver disease, peripheral vascular disease (monitor for progression of arterial obstruction), compromised left ventricular function, heart failure, pheochromocytoma, and myasthenia gravis
Avoid beta-blocker use in non-allergic bronchospasm (e.g., chronic bronchitis and emphysema); if deemed necessary, use with caution and at lowest effective dose
Combined incidence of hypotension, syncope, or dizziness reported in elderly patients (>65 years) switched from highest dose of immediate-release Carviloc (25 mg q12hr) to extended-release Carviloc 80 mg/day
When elderly patients are switched from higher doses of immediate-release Carviloc to extended-release Carviloc, a lower starting dose is recommended
Sudden discontinuance can exacerbate angina and lead to myocardial infarction
Increased risk of stroke after surgery
Dosage should be reduced if bradycardia (HR 98%
Blood pressure drug
Using clonidine with Carviloc can lower your blood pressure and heart rate even further. If you’re switching to Carviloc from clonidine, your doctor will slowly take you off clonidine. You’ll start Carviloc several days after stopping clonidine. If you need both drugs, your doctor will watch you for low blood pressure and low heart rate. If you’re on both drugs and both need to be stopped, your doctor will stop your treatment with Carviloc first and clonidine a few days later.
Carviloc comes in tablets ranging from of 3.125 milligrams (mg) to 25 mg.
It's also available as an extended-release capsule. It's up to your doctor to determine which strength is right for you. You will probably begin with a low dose.
Most people take the tablets twice a day with food; extended-release capsules are usually taken once a day in the morning with food.
Don't chew or crush the capsules or divide up the beads into more than one dose.
If you can't swallow capsules, open the capsule and sprinkle the beads over a spoonful of cool or room temperature applesauce and swallow the entire thing without chewing.
How should I take Carviloc?
Take Carviloc exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Carviloc works best if you take it with food.
You may open the Carviloc capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Discard the empty capsule.
Take Carviloc at the same time every day. Do not skip doses or stop taking Carviloc without first talking to your doctor. Stopping suddenly may make your condition worse.
If you are switched from Carviloc tablets to Carviloc extended-release capsules (Coreg CR), your daily total dose of this medicine may be higher or lower than before. Older adults may be more likely to become dizzy or feel faint when switching from tablets to extended-release capsules. Follow your doctor's instructions.
Your blood pressure will need to be checked often.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
If you need surgery, tell the surgeon ahead of time that you are using Carviloc. You may need to stop using the medicine for a short time.
You should not stop using Carviloc suddenly. Stopping suddenly may make your condition worse.
Carviloc can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Carviloc before surgery unless your surgeon tells you to.
Carviloc is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.
Store at room temperature away from moisture and heat.
How to use Carviloc
See also Warning section.
Read the Patient Information Leaflet if available from your pharmacist before you start taking Carviloc and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with food as directed by your doctor, usually twice daily.
The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
For the treatment of high blood pressure, it may take 1 to 2 weeks before you get the full benefit of this drug. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase, or you have worsening symptoms of heart failure like increased shortness of breath).
Carviloc (Coreg, Coreg CR) drug prescribed to control high blood pressure in addition to a diuretic. Carviloc also may be prescribed in addition with other drugs to manage mild to moderate congestive heart failure and heart disease for patients who have suffered a recent heart attack. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication.