Carlon tablets

Carlon

  • Active Ingredient: Enalapril
  • 10 mg, 5 mg
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What is Carlon?

The active ingredient of Carlon brand is enalapril. Enalapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. C20H28N2O5в€™C4H4O4 M.W. 492.53 Enalapril maleate, USP is an off-white, crystalline powder. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol. Enalapril is a pro-drug; following oral administration, it is bioactivated by hydrolysis of the ethyl ester to enalaprilat, which is the active angiotensin converting enzyme inhibitor. Enalapril maleate tablets USP are supplied as 2.5 mg, 5 mg, 10 mg, and 20 mg tablets for oral administration. In addition, each tablet contains the following inactive ingredients: corn starch, lactose monohydrate, magnesium stearate, pregelatinized starch, and sodium bicarbonate. Each 2.5 mg tablet contains D&C red #27 aluminum lake, D&C yellow #10 aluminum lake, FD&C blue #1 aluminum lake, FD&C red #40 aluminum lake, and FD&C yellow #6 aluminum lake. Each 10 mg tablet contains FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake and FD&C yellow #6 aluminum lake. Each 20 mg tablet contains FD&C Yellow #6.

Used for

Carlon is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, Heart Failure, High Blood Pressure, Hypertensive Emergency, Left Ventricular Dysfunction.

Side Effect

Possible side effects of Carlon include: sweating; Blurred vision; Lack or loss of strength; Chest pain; tightness in the chest; fainting.

How to Buy Carlon tablets online?

To purchase Carlon online - simply click on the "Buy Now" button from the top and follow on to our shop. Payment and Order takes a couple of minutes, and all measures are obvious. We do not take a medical prescription and we have many methods of payment. Considering each detail of rapid shipping and confidentiality, you may read on the applicable pages on the links from the navigation menu.

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Algunos efectos secundarios pueden ser graves. Si experimenta algunos de los siguientes sГ­ntomas, llame a su mГ©dico de inmediato:

  • inflamaciГіn de la cara, la garganta, la lengua, los labios, los ojos, las manos, los pies, los tobillos o las pantorrillas
  • ronquera
  • dificultad para respirar o tragar
  • coloraciГіn amarillenta en la piel o los ojos
  • fiebre, dolor de garganta, escalofrГ­os y otros signos de infecciГіn
  • aturdimiento
  • desvanecimiento

El Carlon puede provocar otros efectos secundarios. Llame a su mГ©dico si tiene algГєn problema inusual mientras toma este medicamento.

Si desarrolla un efecto secundario grave, usted o su doctor puede enviar un informe al programa de divulgaciГіn de efectos adversos 'MedWatch' de la AdministraciГіn de Alimentos y Medicamentos (FDA, por su sigla en inglГ©s) en la pГЎgina de Internet (http://www.fda.gov/Safety/MedWatch) o por telГ©fono al 1-800-332-1088.

Mechanism Of Action

Carlon, after hydrolysis to Carlonat, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The beneficial effects of Carlon in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. Inhibition of ACE results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decreased aldosterone secretion. Although the latter decrease is small, it results in small increases of serum potassium. In hypertensive patients treated with VASOTEC alone for up to 48 weeks, mean increases in serum potassium of approximately 0.2 mEq/L were observed. In patients treated with VASOTEC plus a thiazide diuretic, there was essentially no change in serum potassium (see PRECAUTIONS). Removal of angiotensin II negative feedback on renin secretion leads to increased plasma renin activity.

ACE is identical to kininase, an enzyme that degrades bradykinin. Whether increased levels of bradykinin, a potent vasodepressor peptide, play a role in the therapeutic effects of VASOTEC remains to be elucidated.

While the mechanism through which VASOTEC lowers blood pressure is believed to be primarily suppression of the renin-angiotensin-aldosterone system, VASOTEC is antihypertensive even in patients with low-renin hypertension. Although VASOTEC was antihypertensive in all races studied, black hypertensive patients (usually a low-renin hypertensive population) had a smaller average response to Carlon monotherapy than non-black patients.

Serious side effects

Some people have serious side effects after taking Carlon.

Call a doctor straight away if you get:

  • yellow skin or the whites of your eyes turn yellow - this could be a sign of liver problems
  • paleness, feeling tired, faint or dizzy, any sign of bleeding (like bleeding from the gums or bruising more easily), sore throat and fever and getting infections more easily - these could be signs of a blood or bone marrow disorder
  • a faster or irregular heart rate, chest pain and tightness in your chest - these could be signs of heart problems
  • shortness of breath, wheezing and tightening of the chest - these could be signs of lung problems
  • severe stomach pain that could reach through to your back - this could be a sign of an inflamed pancreas (pancreatitis)
  • swollen ankles, blood in your pee or not peeing at all - these could be signs of kidney problems
  • weak arms and legs or problems speaking - it's important to check these out in case they are signs of a stroke

If you suspect that you or someone else is having a stroke, phone 999 immediately and ask for an ambulance.

Carlon Dosage

Carlon, under the brand name Vasotec, comes in tablet form in 2.5, 5, and 10 milligrams (mg).

For hypertension: the initial dose is usually 5 mg once a day. The dosage range is 10 to 40 mg per day, taken in a single dose or divided into two doses. A diuretic may be added to this as well.

For congestive heart failure: Carlon is often taken with digitalis and diuretics, at an initial dose of 2.5 mg. Doses increase up to a maximum of 40 mg.

For left ventricular dysfunction: the initial dose is 2.5 mg twice a day, up to a maintenance dose of 20 mg.

For pediatric hypertensive patients: the initial dose is .08 mg per kg of body weight, up to not more than 0.58 mg per kg.

Carlon can also be taken as a liquid, with or without food.

¿Qué debo evitar mientras tomo Carlon?

Beber alcohol puede bajar mucho más su presión arterial y puede aumentar ciertos efectos secundarios de Carlon.

No use sustitutos de la sal o suplementos de potasio mientras esté tomando Carlon, salvo que su médico le indique hacerlo.

Evite levantarse muy rápido de la posición de sentado o acostado, ya que puede sentirse mareado. Levántese despacio y estabilícese para evitar que se caiga.

7. Pregnancy and breastfeeding

Carlon is not normally recommended in pregnancy. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

If you're trying to get pregnant or you're already pregnant, talk to your doctor about the benefits and possible harms of taking Carlon. These will depend on how many weeks pregnant you are and the reason you need to take it. There may be other treatments that are safer for you.

Angioedema

Angioedema, including laryngeal edema, may occur at any time during treatment with angiotensin converting enzyme inhibitors, including Carlon. Patients should be so advised and told to report immediately any signs or symptoms suggesting angioedema (swelling of face, extremities, eyes, lips, tongue, difficulty in swallowing or breathing) and to take no more drug until they have consulted with the prescribing physician.

Q: If I am taking Carlon for more than 3 years and it is not helping me, could the doctor change it?

A: Carlon is one of the first line medications that is used for primary hypertension or high blood pressure. I am assuming that you have used it for 3 years and it is no longer helping reduce your blood pressure. If that is the case, your physician may use several other types of medication in order to help reduce your blood pressure, or he or she may increase the dosage of the Carlon. Typically, most physicians will add on a diuretic such as Lasix (furosemide), HCTZ (hydrochlorothiazide) or Dyazide (HCTZ Triamterine). The combination is very effective together in helping to lower the blood pressure. However, depending on your other conditions and medical history he or she may decide on a different medication entirely. Please contact your provider and have this discussion with him or her to find out what would be best for your specific needs. Matt Curley, PharmD

Neonates With A history Of In Utero Exposure To VASOTEC

If oliguria or hypotension occurs, direct attention toward support of blood pressure and renal perfusion. Exchange transfusions or dialysis may be required as a means of reversing hypotension and/or substituting for disordered renal function. Carlon, which crosses the placenta, has been removed from neonatal circulation by peritoneal dialysis with some clinical benefit, and theoretically may be removed by exchange transfusion, although there is no experience with the latter procedure.

Antihypertensive effects of VASOTEC have been established in hypertensive pediatric patients age 1 month to 16 years. Use of VASOTEC in these age groups is supported by evidence from adequate and well-controlled studies of VASOTEC in pediatric and adult patients as well as by published literature in pediatric patients (see CLINICAL PHARMACOLOGY, Clinical Pharmacology in Pediatric Patients and DOSAGE AND ADMINISTRATION).

VASOTEC is not recommended in neonates and in pediatric patients with glomerular filtration rate

Other uses for this medicine

Carlon is also sometimes used to treat kidney disease related to diabetes. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Innovace, Innoz >About Carlon
  • Before taking Carlon
  • How to take Carlon
  • Getting the most from your treatment
  • Can Carlon cause problems?
  • How to store Carlon
  • Important information about all medicines
  • 2. Key facts

    • Carlon lowers your blood pressure and makes it easier for your heart to pump blood around your body.
    • Your first dose of Carlon may make you feel dizzy, so it's best to take it at bedtime. After that, if you don't feel dizzy, you can take it at any time of day.
    • Some people get a dry, irritating cough with Carlon.
    • If you get severe diarrhoea or vomiting from a stomach bug or illness, tell your doctor. You may need to stop taking Carlon for a while until you feel better.
    • Drinking alcohol with Carlon can make you feel dizzy or light-eaded.
    • Carlon is also called by the brand name Innovace. When it's mixed with hydrochlorothiazide, its brand name is Innozide.

    Dosage for high blood pressure

    Adult dosage (ages 18 years and older)

    The starting dose is 5 mg taken by mouth once per day. Your doctor may increase your dose depending on your blood pressure goals. The usual dosage range is 10 to 40 mg per day. Your doctor will decide if you take the drug once or twice per day. The maximum dose is 40 mg per day. If you’re using Carlon with a diuretic, your starting dose should be 2.5 mg taken by mouth once per day.

    Child dosage (ages 1 month–17 years)

    The starting dose is 0.08 mg/kg of body weight taken by mouth once per day (up to 5 mg once per day). Your doctor may increase your dose depending on your blood pressure goals. The maximum dose is 0.58 mg/kg taken by mouth once per day (40 mg once per day).

    Senior dosage (ages 65 years and older)

    There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different schedule.

    Special dosage considerations

    For people with kidney problems:

    • Normal or mild kidney problems: 5 mg taken once per day
    • Moderate to severe kidney problems: 2.5 mg taken once per day. Children with moderate to severe kidney problems should not take Carlon.
    • People on dialysis: 2.5 mg taken once per day on dialysis days. On the days that you don’t have dialysis, your doctor will change your dose based on your blood pressure.


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