TENORMIN® (Canar), a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 - propoxy]-. The molecular and structural formulas are:
Canar (free base) has a molecular weight of 266. It is a relatively polar hydrophilic compound with a water solubility of 26.5 mg/mL at 37°C and a log partition coefficient (octanol/water) of 0.23. It is freely soluble in 1N HCl (300 mg/mL at 25°C) and less soluble in chloroform (3 mg/mL at 25°C).
TENORMIN is available as 25, 50 and 100 mg tablets for oral administration.
Inactive Ingredients: Magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate.
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TENORMIN® (Canar) I.V. Injection
Rated Canar for Hypertension Report
I was dignosed with hypertension and Irregular heartbeat and was prescribed Canar for both. Even though the Canar was effective for both issues, the side effects were terrible! I dealt with tingling in fingers, insomnia, light headiness, dizziness,joint pain, confusion and sometimes I would lose my balance when I would go from sitting to standing. After 8 months of dealing with the side effects I talked with my doctor and I no longer take Canar.
Warnings for other groups
For pregnant women: Canar is a category D pregnancy drug. That means two things:
- Studies show a risk of adverse effects to the fetus when the mother takes the drug.
- The benefits of taking Canar during pregnancy may outweigh the potential risks in certain cases.
Canar use in the second trimester of pregnancy has been associated with birth of babies who are smaller than normal. Also, newborns of mothers who took Canar at the time of birth may be at risk of hypoglycemia (lower than normal blood sugar levels) and bradycardia (slower than normal heartbeat).
If you take Canar and are considering having a baby, or if you are pregnant, talk to your doctor right away. Canar is not the only medication that treats high blood pressure. Other drugs have fewer adverse effects during pregnancy and breastfeeding. Your doctor will be able to tell you if a different drug or a dose adjustment is an option for you.
If you become pregnant while taking this drug, call your doctor right away.
For women who are breastfeeding: Canar is absorbed into breast milk and could be passed to a child who is breastfed. Newborns who breastfeed from mothers who take Canar are also at risk of hypoglycemia and bradycardia.
What should I avoid while taking Canar?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Rated Canar for Hypertension Report
took it for 12 years thanks for another Dr trying to sell meds for the labs, it is all a mafia. There are natural ways to lower your blood pressure. I had 12 years of my life dragging myself to do stuff. I simply QUIT taking it and monitored my BP many times a day, the energy I got back in my life was incredible, don't take it, just look at the long list of side effects, they are REAL. impotence? you bet. and I was thinking was ED, no. was Canar and Simvastatin together. open your eyes people!
Rated Canar for Anxiety Report
I started taking this drug nearly 5 years ago for anxiety and man did it help. I was like a new person such a relief. But slowly did it cause depression. To the point where I am calling the suicide help line. When this all started I saw this exact post from a man who said DO NOT DO THIS IT WILL MAKE YOU WANT TO KILL YOURSELF and I didnt listen. I told my doctor who said nope. HE TOLD ME NOPE NO DEPRESSION. What a peice of crap. Iv been off for a week and feel instantly better. It takes away all your natural adrenaline witch makes you release endorphins the feel good chemical in your brain. I'll take anxiety of this anyday. Sad thing is I reached out to alot of people for help. And no one did. Iam a 32 year old female.
Serious allergic reaction
In rare cases, Canar may cause a serious allergic reaction (anaphylaxis).
Which drugs or supplements interact with Canar?
Calcium channel blockers (CCBs) and digoxin (Lanoxin) can cause lowering of blood pressure and heart rate to dangerous levels when administered together with Canar. Canar can mask the early warning symptoms of low blood sugar (hypoglycemia), and should be used with caution in patients receiving treatment for diabetes.
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More common side effects
The more common side effects of Canar can include:
- cold hands and feet
- reduced sex drive or impotence
- shortness of breath
- unexplained tiredness
- leg pain
- blood pressure that’s lower than usual
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
6. How to cope with s >
What to do about:
- feeling sleepy, tired or dizzy - as your body gets used to Canar, these side effects should wear off. If Canar makes you feel dizzy, sit or lie down until you feel better. Do not drive or operate machinery until you feel OK again. Try to avoid alcohol as it'll make you feel worse.
- cold fingers or toes - put your hands or feet under warm running water, massage them and wiggle your fingers and toes. Do not smoke or have drinks with caffeine in - this can make your blood vessels narrower and further restrict blood flow to your hands and feet. Try wearing mittens (they're warmer than gloves) and warm socks. Do not wear tight watches or bracelets.
- feeling sick (nausea) - stick to simple meals and do not eat rich or spicy food. It might help to take your Canar after a meal or snack.
- diarrhoea - drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
- constipation - eat more high-fibre foods, such as fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise more regularly by going for a daily walk, for example. If this does not help, talk to your pharmacist or doctor. Watch this short video about how to treat constipation
How to take it
Canar does not usually upset your tummy, so you can take it with or without food. It's best to do the same each day.
Swallow the tablets whole with a drink of water.
If you find them difficult to swallow, some brands have a score line to help you break the tablet in half. Check the information leaflet for your brand to see if you can do this.
If you're taking Canar as a liquid, it'll come with a plastic syringe or spoon to help you measure out the right dose.
If you do not have one, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not give you the right amount of medicine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Canar only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2019 Cerner Multum, Inc. Version: 9.01.
El Canar puede provocar efectos secundarios. DГgale a su doctor si cualquiera de estos sГntomas se vuelve severo o si no desaparece:
- somnolencia (sueГ±o)
- malestar estomacal
Heart rhythm drugs
Taking certain heart drugs with Canar can slow down your heart rate too much. Examples of these drugs include:
Canar is excreted in human breast milk at a ratio of 1.5 to 6.8 when compared to the concentration in plasma. Caution should be exercised when TENORMIN is administered to a nursing woman. Clinically significant bradycardia has been reported in breast-fed infants. Premature infants, or infants with impaired renal function, may be more likely to develop adverse effects.
Neonates born to mothers who are receiving TENORMIN at parturition or breast-feeding may be at risk for hypoglycemia and bradycardia. Caution should be exercised when TENORMIN is administered during pregnancy or to a woman who is breast-feeding (see WARNINGS, Pregnancy and Fetal Injury).