Carcinogenesis, Mutagenesis, Impairment Of Fertility
Two long-term (maximum dosing duration of 18 or 24 months) rat studies and one long-term (maximum dosing duration of 18 months) mouse study, each employing dose levels as high as 300 mg/kg/day or 150 times the maximum recommended human antihypertensive dose,* did not indicate a carcinogenic potential of Atendal. A third (24 month) rat study, employing doses of 500 and 1,500 mg/kg/day (250 and 750 times the maximum recommended human antihypertensive dose*) resulted in increased incidences of benign adrenal medullary tumors in males and females, mammary fibroadenomas in females, and anterior pituitary adenomas and thyroid parafollicular cell carcinomas in males. No evidence of a mutagenic potential of Atendal was uncovered in the dominant lethal test (mouse), in vivo cytogenetics test (Chinese hamster) or Ames test (S typhimurium).
Fertility of male or female rats (evaluated at dose levels as high as 200 mg/kg/day or 100 times the maximum recommended human dose*) was unaffected by Atendal administration.
Where can I get more information (Tenormin)?
Your pharmacist can provide more information about Atendal.
8. Cautions with other medicines
There are some medicines that may interfere with the way Atendal works.
Tell your doctor if you're taking:
- other medicines for high blood pressure - the combination with Atendal can sometimes lower your blood pressure too much, which may make you feel dizzy or faint; tell your doctor if this keeps happening to you, as they may change your dose
- other medicines for an irregular heartbeat, such as amiodarone or flecainide
- medicines for asthma or chronic obstructive pulmonary disease (COPD)
- medicines for diabetes, particularly insulin - Atendal may make it more difficult to recognise the warning signs of low blood sugar; speak to your doctor if you have low blood sugar levels without getting any of the usual warning signs (you should check your blood sugar after exercise and follow the usual advice about checking it before driving or operating machinery)
- medicines to treat nose or sinus congestion, or other cold remedies (including those you can buy in a pharmacy)
- medicines for allergies, such as ephedrine, noradrenaline or adrenaline
Mixing Atendal with herbal remedies or supplements
There's very little information about taking herbal remedies and supplements with Atendal.
Calcium channel blockers
Like Atendal, these drugs are used to treat high blood pressure and several other heart problems. If combined with Atendal, they may reduce the contractions of your heart and slow it down more. Doctors sometimes use this combination under close supervision. Examples of these drugs include:
Before taking Atendal
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking Atendal it is important that your doctor knows:
- If you are pregnant or breastfeeding.
- If you have asthma or any other breathing disorder.
- If you have any problems with the way your k >
Rated Atendal for Hypertension Report
I've been on this medicine for about 2 weeks for hypertention and irregular heart beat. it did help with the bp issue but the side effects..I can't deal..the biggest side effect is tightness in the chest..and it seems like it makes my heart beat faster. anybody else experience these side effects?? Im going to STOP taking this medicine immediately and talk to my doctor!!
6. How to cope with s >
What to do about:
- feeling sleepy, tired or dizzy - as your body gets used to Atendal, these side effects should wear off. If Atendal makes you feel dizzy, sit or lie down until you feel better. Do not drive or operate machinery until you feel OK again. Try to avoid alcohol as it'll make you feel worse.
- cold fingers or toes - put your hands or feet under warm running water, massage them and wiggle your fingers and toes. Do not smoke or have drinks with caffeine in - this can make your blood vessels narrower and further restrict blood flow to your hands and feet. Try wearing mittens (they're warmer than gloves) and warm socks. Do not wear tight watches or bracelets.
- feeling sick (nausea) - stick to simple meals and do not eat rich or spicy food. It might help to take your Atendal after a meal or snack.
- diarrhoea - drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
- constipation - eat more high-fibre foods, such as fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise more regularly by going for a daily walk, for example. If this does not help, talk to your pharmacist or doctor. Watch this short video about how to treat constipation
What is the most important information I should know about Atendal (Tenormin)?
You should not use this medicine if you have a serious heart condition such as "AV block," very slow heartbeats, or heart failure.
How much will I take?
How much you take depends on why you need Atendal.
- For high blood pressure - the usual dose is 25mg to 50mg taken once a day.
- For angina (chest pain) - the usual dose is 100mg taken once a day, or split into 2 50mg doses.
- For irregular heartbeats (arrhythmia) - the usual dose is 50mg to 100mg taken once a day.
- For migraine - the usual dose is 25mg to 100mg taken twice a day. Doctors sometimes prescribe Atendal for migraine, but it's not officially approved for preventing it.
For children taking Atendal, your child's doctor will work out the right dose by using their weight and age.
What are the possible side effects of Atendal (Tenormin)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- new or worsening chest pain;
- slow or uneven heartbeats;
- a light-headed feeling, like you might pass out;
- shortness of breath (even with mild exertion), swelling, rapid weight gain; or
- a cold feeling in your hands and feet.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Rated Atendal for Hypertension Report
I took Atendal for 15 years for high blood pressure. Worst decision I ever made! I had quite a few low grade side effects and over the years it got worse and worse. I didn’t realize it was this medication because I had taken it so long. The last three and a half years I had a lot of serious medical problems, my glands were extremely swollen and painful, I lost the ability to smell, I had severe diarrhea and pain. I literally was a the point of death! I had thirteen different drs and specialist, seven different procedures, nine different kinds of medications all in hopes of healing me. Nothing worked until I stopped taking Atendal! Not one of the drs even questioned the Atendal, only by God’s grace did I look at the side effects online. I saw my dr and got a different blood pressure medication and within the first day of stopping Atendal I felt relief! It’s been three weeks since I stopped taking Atendal and I am improving everyday, my only worry now is that some of the damage this pill caused me is not permanent!