More common side effects
The more common side effects that can occur with Prostafin include:
- decreased sex drive
- trouble getting or keeping an erection
- ejaculation disorder
- increase in breast size and tenderness
- skin rash
If these effects are mild, they may disappear within a few days or a couple of weeks. If they’re more severe or don’t disappear, talk to your doctor or pharmacist.
- Store Prostafin at room temperature between 59°F and 86°F (15°C and 30°C).
- Keep it away from light and high temperature.
- Don’t store this medication in moist or damp areas, such as bathrooms.
WHAT IS FINASTERIDE
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It offers you the most extensive product information and up-to-date resources regarding this medication, including related news articles, medical studies, an image library and all the necessary information on dosage and side effects.
Whether you are an average consumer or a pharma industry professional, you can now find out everything you need to know about Prostafin on this reference site, as well as take part in our open discussion forum by sharing your own knowledge and experience with people who are using this medication.
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Warnings for other groups
For pregnant women: This drug is not prescribed for use in women, and should never be used during pregnancy.
For women who are breastfeeding: Prostafin should never be used in breastfeeding women. It isn’t known if Prostafin passes through breast milk.
This drug is not prescribed for use in women.
For children: The safety and effectiveness of Prostafin in children haven’t been established. This drug is not prescribed for use in children.
All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:
- your age
- the condition being treated
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
The following additional adverse events have been reported in postmarketing experience with PROSCAR. Because these events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure:
- hypersensitivity reactions, such as pruritus, urticaria, and angioedema (including swelling of the lips, tongue, throat, and face)
- testicular pain
- sexual dysfunction that continued after discontinuation of treatment, including erectile dysfunction, decreased libido and ejaculation disorders (e.g. reduced ejaculate volume). These events were reported rarely in men taking PROSCAR for the treatment of BPH. Most men were older and were taking concomitant medications and/or had co-morbid conditions. The independent role of PROSCAR in these events is unknown.
- male infertility and/or poor seminal quality were reported rarely in men taking PROSCAR for the treatment of BPH. Normalization or improvement of poor seminal quality has been reported after discontinuation of Prostafin. The independent role of PROSCAR in these events is unknown.
- male breast cancer
The following additional adverse event related to sexual dysfunction that continued after discontinuation of treatment has been reported in postmarketing experience with Prostafin at lower doses used to treat male pattern baldness. Because the event is reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate its frequency or establish a causal relationship to drug exposure:
Prostafin, sold under the brand names Proscar and Propecia among others, is a medication used for the treatment of benign prostatic hyperplasia (enlarged prostate) and pattern hair loss.
In the US, Prostafin (Prostafin systemic) is a member of the drug class 5-alpha-reductase inhibitors and is used to treat Androgenetic Alopecia and Benign Prostatic Hyperplasia.
Mechanism Of Action
The development and enlargement of the prostate gland is dependent on the potent androgen, 5α- dihydrotestosterone (DHT). Type II 5α-reductase metabolizes testosterone to DHT in the prostate gland, liver and skin. DHT induces androgenic effects by binding to androgen receptors in the cell nuclei of these organs.
Prostafin is a competitive and specific inhibitor of Type II 5α-reductase with which it slowly forms a stable enzyme complex. Turnover from this complex is extremely slow (t½
30 days). This has been demonstrated both in vivo and in vitro. Prostafin has no affinity for the androgen receptor. In man, the 5α-reduced steroid metabolites in blood and urine are decreased after administration of Prostafin.
Mean steady-state volume of distribution was 76 liters (range, 44-96 liters). Approximately 90% of circulating finaster >
Prostafin has been shown to cross the blood brain barrier but does not appear to distribute preferentially to the CSF.
In 2 studies of healthy subjects (n=69) receiving PROSCAR 5 mg/day for 6-24 weeks, Prostafin concentrations in semen ranged from undetectable ( 14 C-finaster >
The mean terminal half-life of finaster >
Table 3: Mean (SD) Pharmacokinetic Parameters in Healthy Young Subjects (n=15)
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- swelling of your lips, tongue, throat, or face
- lumps or pain in your breasts
- nipple discharge
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.
To find out how Prostafin oral tablet might interact with something else you’re taking, talk to your doctor or pharmacist.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we can not guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
This drug comes with several warnings.