Prostacide tablets

Prostacide

  • Active Ingredient: Finasteride
  • 5 mg, 1 mg
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What is Prostacide?

The active ingredient of Prostacide brand is finasteride. Finasteride prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH). Finasteride is a white crystalline powder with a melting point near 250В°C. It is freely soluble in chloroform and in lower alcohol solvents, but is practically insoluble in water. Finasteride tablets USP for oral administration are film-coated tablets that contain 5 mg of Finasteride and the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, docusate sodium, magnesium stearate, opadry blue (FD&C blue #2 aluminium lake, hypromellose, talc, titanium dioxide, yellow iron oxide). The botanical source of the Pregelatinized Starch is Maize

Used for

Prostacide is used to treat diseases such as: Androgenetic Alopecia, Benign Prostatic Hyperplasia.

Side Effect

Possible side effects of Prostacide include: rapid weight gain; inability to have or keep an erection; diarrhea; dizziness; dizziness, faintness, or lightheadedness when getting up from a lying or sitting position; loss in sexual ability, desire, drive, or performance.

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What are some other side effects of Prostacide 5 mg Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling dizzy, tired, or weak.
  • This medicine may cause a change in sex ability in men or lowered interest in sex. This could go on after you stop this medicine (Prostacide 5 mg tablets). Talk with your doctor if these effects go on or bother you.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Pharmacodynamics

In man, a single 5-mg oral dose of PROSCAR produces a rap >

In patients receiving PROSCAR 5 mg/day, increases of about 10% were observed in luteinizing hormone (LH) and follicle-stimulating hormone (FSH), but levels remained within the normal range. In healthy volunteers, treatment with PROSCAR did not alter the response of LH and FSH to gonadotropin-releasing hormone indicating that the hypothalamic-pituitary-testicular axis was not affected.

In patients with BPH, PROSCAR has no effect on circulating levels of cortisol, prolactin, thyroidstimulating hormone, or thyroxine. No clinically meaningful effect was observed on the plasma lipid profile (i.e., total cholesterol, low density lipoproteins, high density lipoproteins and triglycerides) or bone mineral density.

Adult males with genetically inherited Type II 5α-reductase deficiency also have decreased levels of DHT. Except for the associated urogenital defects present at birth, no other clinical abnormalities related to Type II 5α-reductase deficiency have been observed in these individuals. These individuals have a small prostate gland throughout life and do not develop BPH.

In patients with BPH treated with Prostacide (1-100 mg/day) for 7-10 days prior to prostatectomy, an approximate 80% lower DHT content was measured in prostatic tissue removed at surgery, compared to placebo; testosterone tissue concentration was increased up to 10 times over pretreatment levels, relative to placebo. Intraprostatic content of PSA was also decreased.

In healthy male volunteers treated with PROSCAR for 14 days, discontinuation of therapy resulted in a return of DHT levels to pretreatment levels in approximately 2 weeks. In patients treated for three months, prostate volume, which declined by approximately 20%, returned to close to baseline value after approximately three months of discontinuation of therapy.

Avoid Prostacide to save money and reduce risk of high-grade disease

Dr. Walsh has been greatly troubled by the pressure for patients and general physicians to use Prostacide. His conclusions about this drug include:

  • It has no primary effect in reducing the number of men who will have a positive biopsy.
  • Patients will believe that it prevents cancer, will be pleased that their PSA levels fall and will not understand the potential danger of developing undiagnosed, high-grade disease.
  • Prostacide can be used as a treatment for an enlarged prostate, as long as patients who are being screened for prostate cancer understand the guidelines. If you don’t want to know if you have prostate cancer, you should just avoid PSA testing.

According to Dr. Walsh, if you want to prevent prostate cancer, Prostacide is the last thing you should take. Save yourself the yearly cost of the medication and avoid the increased risk of high-grade disease. The only thing that Prostacide can do is prevent you from knowing that you may have lethal cancer until it may be too late to cure.

How to Determine Your Real PSA Level

If you are taking Prostacide, you need to be able to determine your actual PSA level.

If you have been taking the drug for:

  • Two years: Multiply your PSA by 2
  • Between two and seven years: Multiply your PSA by 2.3
  • More than seven years: Multiply your PSA by 2.5

If your PSA begins to rise, get a biopsy immediately.

Genitourinary

Most men were older and were taking concomitant medications and/or had comorbid conditions:

Very common (10% or more): Impotence (up to 18.5%)

Common (1% to 10%): Abnormal ejaculation, decreased ejaculatory volume, abnormal sexual function, gynecomastia, erectile dysfunction, ejaculation disorder, testicular pain, male infertility and/or poor seminal quality

Two hundred fourteen reports of gynecomastia in men taking Prostacide in the United States were received by the FDA between June 1992 and February 1995. Among those reported, fifty eight percent were taking additional medications that have been associated with gynecomastia. Sixty nine of 86 patients who discontinued Prostacide treatment had partial or complete remission.

New reports of drug-related sexual adverse experiences have been reported to decrease with duration of therapy.

Erectile dysfunction has been reported to continue beyond treatment discontinuation. Normalization or improvement of seminal quality has been reported after withdrawing Prostacide treatment.

Contact with drug warning

Prostacide may be passed through the skin. Pregnant women and women who plan to become pregnant in the near future shouldn’t handle this drug. Doing so could cause birth defects.

For the Consumer

Applies to Prostacide: oral tablet

Along with its needed effects, Prostacide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking Prostacide:

  • Chills
  • cold sweats
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • breast enlargement and tenderness
  • hives or welts
  • itchy skin
  • rapid weight gain
  • redness of the skin
  • skin rash
  • swelling of the lips and face
  • tingling of the hands or feet
  • unusual weight gain or loss

Incidence not known

  • Clear or bloody discharge from the nipple
  • dimpling of the breast skin
  • inverted nipple
  • lump in the breast or under the arm
  • persistent crusting or scaling of the nipple
  • redness or swelling of the breast
  • sore on the skin of the breast that does not heal

Some side effects of Prostacide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Decreased interest in sexual intercourse
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance

  • Runny nose
  • sleepiness or unusual drowsiness
  • sneezing
  • stuffy nose

Less common or rare

Incidence not known

Prostacide should be stored at room temperature in a tight, light resistant container.

Prostacide is available in generic form, but you must have a prescription from your doctor or other health-care professional to obtain the drug.

How to use Prostacide

Read the Patient Information Leaflet provided by your pharmacist before you start taking Prostacide and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.

Take this medication by mouth, with or without food, usually once a day, or as directed by your doctor.

If the tablet is crushed or broken, it should not be handled by a woman who is pregnant or by a woman who may become pregnant (see also Precautions section).

Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Do not stop taking this medication without consulting your doctor.

It may take 6-12 months to notice a benefit.

Inform your doctor if your condition persists or worsens.


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