Zipantola tablets

Zipantola

  • Active Ingredient: Pantoprazole
  • 40 mg, 20 mg
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What is Zipantola?

The active ingredient of Zipantola brand is pantoprazole. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole sodium USP is a white to off-white powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium USP is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5 and approximately 220 hours at pH 7.8. Pantoprazole sodium USP is supplied as a delayed-release tablet, available in two strengths 20 mg Pantoprazole (equivalent to 22.56 mg of Pantoprazole sodium USP) and 40 mg Pantoprazole (equivalent to 45.1 mg of Pantoprazole sodium USP). Pantoprazole sodium delayed-release tablets, USP contain the following inactive ingredients: calcium stearate, crospovidone, ferric oxide, hydroxypropyl cellulose, hypromellose, mannitol, methacrylic acid copolymer dispersion, sodium carbonate, and triethyl citrate. The tablets are imprinted with brown ink containing ammonium hydroxide, iron oxide black, iron oxide red, iron oxide yellow, isopropyl alcohol, N-butyl alcohol, propylene glycol, and shellac glaze in ethanol. Pantoprazole sodium delayed-release tablets (40 mg and 20 mg) complies USP dissolution test 3.

Used for

Zipantola is used to treat diseases such as: Barrett's Esophagus, Dumping Syndrome, Duodenal Ulcer, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Peptic Ulcer, Stomach Ulcer, Stress Ulcer Prophylaxis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Zipantola include: dry mouth; stomach pain, continuing; hives, itching, or skin rash; sores, ulcers, or white spots on the lips or in the mouth; difficulty with speaking; trembling; blurred vision; muscle pain or stiffness.

How to Buy Zipantola tablets online?

To purchase Zipantola online - simply click on the "Buy Now" button in the top and follow along with our shop. Payment and Order takes a few minutes, and all measures are evident. We don't require a medical prescription and we have many procedures of payment. With each detail of fast delivery and confidentiality, then you may read on the relevant pages on the hyperlinks in the top menu.

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What should I discuss with my healthcare provider before using Zipantola (Protonix, Protonix IV)?

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not use this medicine if:

  • you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); or
  • you are allergic to Zipantola or similar medicines (lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, and others).

Tell your doctor if you have ever had:

  • low levels of magnesium in your blood;
  • lupus; or
  • osteoporosis or low bone mineral density.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using this medicine.

Zipantola is not approved for use by anyone younger than 5 years old.

7. Pregnancy and breastfeeding

Zipantola isn't usually recommended during pregnancy as there's no firm evidence it's safe.

A medicine called omeprazole, which is similar to Zipantola, is safe in pregnancy.

However, if you're pregnant, it's better to try to treat your symptoms without taking a medicine.

Your doctor or midwife may suggest eating smaller meals more often and avoiding fatty and spicy foods.

They may also suggest that you raise the head of your bed 10 to 20cm by putting something under your bed or mattress, so that your chest and head are above your waist. This helps stop stomach acid travelling up towards your throat.

If these lifestyle changes don't work, you may be recommended omeprazole, which is safe to take during pregnancy.

What are the uses for Protonix?

Zipantola is approved for:

  • Treating gastroesophageal reflux disease (GERD)
  • Treating ulcers of the stomach (peptic) and duodenum
  • Healing erosive esophagitis
  • Treating Zollinger-Ellison syndrome

DESCRIPTION

The active ingredient in PROTONIX (Zipantola sodium) For Delayed-Release Oral Suspension and PROTONIX (Zipantola sodium) Delayed-Release Tablets, a PPI, is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2- sulfinyl]-1H-benzimidazole sesquihydrate, a compound that inhibits gastric acid secretion. Its empirical formula is C16H14F2N3NaO4S x 1.5 H2O, with a molecular weight of 432.4. The structural formula is:

Zipantola sodium sesquihydrate is a white to off-white crystalline powder and is racemic. Zipantola has weakly basic and acidic properties. Zipantola sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane.

The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5 and approximately 220 hours at pH 7.8.

PROTONIX is supplied as a for delayed-release oral suspension in unit dose packets, available in one strength (40 mg) Zipantola, (equivalent to 45.1 mg of Zipantola sodium), and as a delayed-release tablet, available in two strengths 20 mg Zipantola (equivalent to 22.56 mg of Zipantola sodium) and 40 mg Zipantola (equivalent to 45.1 mg of Zipantola sodium).

PROTONIX Delayed-Release Tablets contain the following inactive ingredients: calcium stearate, crospovidone, hypromellose, iron oxide, mannitol, methacrylic acid copolymer, polysorbate 80, povidone, propylene glycol, sodium carbonate, sodium lauryl sulfate, titanium dioxide, and triethyl citrate. PROTONIX Delayed-Release Tablets (40 mg and 20 mg) complies with USP dissolution test 2.

PROTONIX For Delayed-Release Oral Suspension contains the following inactive ingredients: crospovidone, hypromellose, methacrylic acid copolymer, microcrystalline cellulose, polysorbate 80, povidone, sodium carbonate, sodium lauryl sulfate, talc, titanium dioxide, triethyl citrate, and yellow ferric oxide.

How much will I take?

Each tablet contains 20mg or 40mg of Zipantola. You can buy Zipantola 20mg tablets from pharmacies. These are suitable for the short-term treatment of heartburn and acid reflux in adults.

Liquid Zipantola can be prescribed for people who cannot swallow tablets. It will come with a syringe or spoon to help you take the right amount. If you don't have a syringe or spoon, ask your pharmacist for one.

The usual dose to treat:

  • heartburn and acid reflux is 20mg a day
  • gastro-oesophageal reflux disease is 20mg to 40mg a day
  • stomach ulcers is 20mg to 40mg a day
  • Zollinger-Ellison syndrome is 40mg to 80mg a day - this can increase to 160mg a day depending on how well it works for you

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Proton pump inhibitors such as Zipantola stop cells in the lining of the stomach from producing too much acid. This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn. Zipantola is also given as one part of a treatment to get rid of Helicobacter pylori, a bacterium found in the stomach, which can cause ulcers.

Zipantola is available on prescription. You can also buy short courses of Zipantola at a pharmacy for the treatment of reflux symptoms (such as heartburn) in adults.


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