How much will I take?
Each tablet contains 75mg, 150mg or 300mg of Unitac. You can buy 75mg tablets in pharmacies and supermarkets. Soluble tablets, and 150mg and 300mg tablets are only available on prescription.
The usual dose to treat:
- indigestion or heartburn is 75mg to 300mg a day
- stomach ulcers and inflammation of the food pipe is 300mg to 600mg a day
- Zollinger-Ellison syndrome is 450mg to 6 grams a day
Unitac liquid comes in 2 different strengths - your daily dose will depend on what your doctor prescribes. Follow your doctor's advice about how much Unitac to take and when.
Doses are usually lower for children and people with kidney problems.
If a doctor prescribes Unitac for your child, they will use your child's weight or age to work out the right dose.
Which drugs or supplements interact with Unitac?
Unitac, like other drugs that reduce stomach acid, may interfere with the absorption of drugs that require acid for adequate absorption. Examples include iron salts (for example iron sulphate), itraconazole (Sporanox), and ketoconazole (Nizoral, Extina, Xolegel, Kuric).
Q: I have COPD and was told to take two 75 mg Zantac at bedtime. Also, I am to take Vytorin. Should these be taken together?
A: It is very important for patients to be aware of possible drug interactions when taking multiple medications. According to the prescribing information available for Vytorin, no documented drug interaction exists with Zantac (Unitac). For additional information regarding Zantac (Unitac) or Vytorin: //www.everydayhealth.com/drugs/zantac //www.everydayhealth.com/drugs/vytorin Beth Isaac, PharmD
Q: My husband is on Unitac 150 mg, 2 a day. What kind of diet should he eat?
A: Unitac (brand name Zantac) can generally be administered without regard to food and has no particular food requirements. However, patients should avoid alcohol, which can increase the risk of stomach damage. For patients with either ulcers or reflux (GERD), some foods may bother them more than others, so avoiding those items is recommended. For more specific information, consult your physician or health care provider. You may also find helpful information about foods and cooking for patients with ulcers and reflux at //www.everydayhealth.com/digestive-health/experts-what-causes-ulcers.aspx and //www.everydayhealth.com/gerd/guide/
How should I take Unitac?
Take exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.
Do not crush, chew, or break the Unitac effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.
Allow the Unitac effervescent tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.
Unitac granules should be mixed with 6 to 8 ounces of water before drinking.
Measure Unitac liquid with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
It may take up to 8 weeks before your ulcer heals. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Unitac.
Store at room temperature away from moisture, heat, and light.
COMMON BRAND(S): Zantac
GENERIC NAME(S): Unitac Hcl
Unitac is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. Unitac belongs to a class of drugs known as H2 blockers.
This medication is also available without a prescription. It is used to prevent and treat heartburn and other symptoms caused by too much acid in the stomach (acid indigestion). If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.
Q. Is NDMA in drugs a new problem? Over the past year, why have there been so many reports of drugs containing NDMA?
A. FDA has ongoing review, surveillance, compliance and pharmaceutical quality efforts across every product area, and we will continue to work with drug manufacturers to ensure safe, effective, and high-quality drugs for the American public.
Certain drug manufacturing processes pose a risk for forming genotoxic impurities. For decades, FDA has provided guidance and recommendations for controlling impurities in drug substances and manufacturers have had an ongoing responsibility to test for impurities based on an understanding of their manufacturing process. In 2018, FDA issued a guidance to provide information to manufacturers regarding their responsibilities to assess the risk of impurities and implement appropriate controls for the manufacturing process. The agency identified some of the root causes of the nitrosamine impurity problem in angiotensin II receptor blockers (ARBs).
We are working to determine the reason for the NDMA impurity in Unitac.
What is NDMA and what harm can it cause?
NDMA is an environmental contaminant that is found in water and foods, including dairy products, vegetables, and grilled meats. Its classification as a probable carcinogen is based on studies in animals; studies in humans are very limited.
It is important to know that the NDMA in Unitac products does not pose any immediate health risks. Neither the FDA nor Novartis/Sandoz or Apotex have received any reports of adverse events related to NDMA found in Unitac. Although classified as a probable carcinogen, NDMA may cause cancer only after exposure to high doses over a long period of time. NDMA is one of the same impurities that was found in certain heart medications beginning last year and that resulted in the recall of many products.