Before taking this medicine
Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.
You should not use this medicine if:
you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); or
you are allergic to Ugarpan or similar medicines (lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, and others).
Tell your doctor if you have ever had:
low levels of magnesium in your blood;
osteoporosis or low bone mineral density.
You may be more likely to have a broken bone while using Ugarpan long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy, especially if you are an adult over 50.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breast-feed while using this medicine.
Ugarpan is not approved for use by anyone younger than 5 years old.
Before taking Ugarpan, tell your doctor and pharmacist about all medications you are taking (including vitamins and herbal supplements).
Ugarpan shouldn't be taken with atazanavir (Reyataz) or nelfinavir (Viracept), which are medications used to treat HIV and AIDS.
Other drugs that may interact with Ugarpan include:
- Ampicillin (Omnipen, Principen, Amcill)
- Warfarin (Coumadin, Jantoven)
- Digoxin (Lanoxin, Lanoxicaps)
- Diuretics (water pills)
- Antifungals such as ketoconazole (Nizoral), itraconazole (Sporanox), and voriconazole (Vfend)
- Iron supplements/ferrous sulfate (Feosol, Mol-Iron, Fergon, Femiron)
- Methotrexate (Trexall)
- Delavirdine (Rescriptor)
Unless otherwise instructed, you can continue a normal diet and normal activities while taking Ugarpan.
Getting the most from your treatment
What should I avoid while using Ugarpan (Protonix, Protonix IV)?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Taking Ugarpan can lead to a kidney condition called acute interstitial nephritis. This may occur in people with a sensitivity to PPIs.
If a doctor detects this condition, they will stop the medication immediately.
What other drugs will affect Ugarpan?
Tell your doctor about all your other medicines. Some may interact with Ugarpan, especially:
a diuretic or "water pill."
This list is not complete. Other drugs may affect Ugarpan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Ugarpan shouldn't be used for the immediate relief of heartburn symptoms.
Don't take Ugarpan if you're allergic to any other benzimidazole medications such as albendazole (Albenza) or mebendazole (Vermox).
Long-term use of Ugarpan may make it harder for your body to absorb vitamin B-12, which could result in a B-12 deficiency.
PPI use may also increase your risk for fractures in your wrists, hips, or spine. In 2010, however, the FDA decided that there was not enough evidence of fracture risk to merit a warning.
Extended use of Ugarpan has been shown to cause stomach cancer in animal studies, but researchers are unsure if the medication has the same effects in humans.
Ugarpan may be used in children five years of age and older for up to eight weeks to heal acid-related damage to the esophagus. It's not known if the drug is safe for longer than eight weeks of use in children.
Tell your doctor if you are allergic to any of the ingredients in Ugarpan. You can ask your pharmacist for a list of the ingredients.
How to store Ugarpan
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Why it’s used
Ugarpan oral tablet is used to reduce the amount of stomach acid your body makes. It helps treat painful symptoms caused by conditions such as gastroesophageal reflux disease (GERD). With GERD, gastric juices flow upward from your stomach and into the esophagus.
Ugarpan oral tablet is also used to treat other conditions in which the stomach makes excess acid, such as Zollinger-Ellison syndrome.
By Julie Marks | Medically Reviewed by Ruthan White, PharmD
Latest Update: 2014-08-14 Copyright © 2014 Everyday Health Media, LLC
Ugarpan and metabolites are excreted in milk of rats. Ugarpan excretion in human milk has been detected in a study of a single nursing mother after a single 40 mg oral dose of Ugarpan sodium; clinical relevance of this finding not known; many drugs excreted in human milk have potential for serious adverse reactions in nursing infants; based on potential for tumorigenicity shown for Ugarpan sodium in rodent carcinogenicity studies, a decision should be made whether to discontinue nursing or to discontinue drug, taking into account benefit of drug to mother
COMMON BRAND(S): Protonix
GENERIC NAME(S): Ugarpan
OTHER NAME(S): Ugarpan Tablet, Delayed Release (Enteric Coated)
Ugarpan is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Ugarpan belongs to a class of drugs known as proton pump inhibitors (PPIs).
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Taking methotrexate with Ugarpan may increase the amount of methotrexate in your body. If you’re taking high doses of methotrexate, your doctor may have you stop taking Ugarpan during your methotrexate therapy.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you’re taking.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ugarpan only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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