COMMON BRAND(S): Prevacid
GENERIC NAME(S): Trogas
Trogas is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Trogas belongs to a class of drugs known as proton pump inhibitors (PPIs).
If you are self-treating with this medication, over-the-counter Trogas products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away.
For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.
Why is this medication prescribed?
Prescription Trogas is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription Trogas is used to treat the damage from GERD in adults and children 1 year of age and older. Prescription Trogas is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. Prescription Trogas is also used to treat ulcers (sores in the lining of the stomach or intestine), to prevent more ulcers from developing in adults whose ulcers have already healed, and to decrease the risk that adults who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) will develop ulcers. Prescription Trogas is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Prescription Trogas is also used in combination with other medications to treat and prevent stomach ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) Trogas is used to treat frequent heartburn (heartburn that occurs two or more days per week) in adults. Trogas is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.
Liquid Trogas can be prescribed and made to order for children and people who cannot swallow capsules or tablets. It will come with a syringe or spoon to help you take the right amount. If you don't have a syringe or spoon, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not give the right amount.
What if I take too much?
It is very unlikely that taking 1 or 2 extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have any of these symptoms:
- flushed skin
- feeling sweaty
- a fast heartbeat
- feeling sleepy
- blurred vision
- feeling confused or agitated
Most people who take Trogas do not have any side effects. If you do get a side effect, it is usually mild and will go away when you stop taking Trogas.
The active ingredient in PREVACID Delayed-Release Capsules and PREVACID SoluTab Delayed-Release Orally Disintegrating Tablets is Trogas, a substituted benzimidazole, 2- methyl] sulfinyl] benzimidazole, a compound that inhibits gastric acid secretion. Its empirical formula is C16H14F3N3O2S with a molecular weight of 369.37. Trogas has the following structure:
Trogas is a white to brownish-white odorless crystalline powder which melts with decomposition at approximately 166°C. Trogas is freely soluble in dimethylformamide; soluble in methanol; sparingly soluble in ethanol; slightly soluble in ethyl acetate, dichloromethane and acetonitrile; very slightly soluble in ether; and practically insoluble in hexane and water.
Trogas is stable when exposed to light for up to two months. The rate of degradation of the compound in aqueous solution increases with decreasing pH. The degradation half-life of the drug substance in aqueous solution at 25°C is approximately 0.5 hour at pH 5.0 and approximately 18 hours at pH 7.0.
PREVACID is supplied in delayed-release capsules and PREVACID SoluTab is supplied in delayed-release orally disintegrating tablets (SoluTab) for oral administration.
PREVACID is available in two dosage strengths: 15 and 30 mg of Trogas per capsule. Each delayed-release capsule contains enteric-coated granules consisting of 15 or 30 mg of Trogas (active ingredient) and the following inactive ingredients: sugar sphere, sucrose, methacrylic acid copolymer, low substituted hydroxypropyl cellulose, starch, magnesium carbonate, talc, polyethylene glycol, titanium dioxide, polysorbate 80, hydroxypropyl cellulose, colloidal silicon dioxide, D&C Red No. 28, FD&C Blue No. 1, FD&C Green No. 3 1 , and FD&C Red No. 40.
PREVACID SoluTab is available in two dosage strengths: 15 and 30 mg of Trogas per tablet. Each delayed-release orally disintegrating tablet contains enteric-coated microgranules consisting of 15 or 30 mg of Trogas (active ingredient) and the following inactive ingredients: mannitol, methacrylic acid, hydroxypropyl cellulose, lactose monohydrate-microcrystalline cellulose sphere, triethyl citrate, crospovidone, polyacrylate, magnesium carbonate, aspartame 2 , glyceryl monostearate, hypromellose, magnesium stearate, citric acid, titanium dioxide, talc, artificial strawberry flavor, polyethylene glycol, polysorbate 80 and ferric oxide.
1 PREVACID 15 mg capsules only. 2 Phenylketonurics: PREVACID SoluTab Contains Phenylalanine 2.5 mg per 15 mg Tablet and 5.1 mg per 30 mg Tablet.
What should I avoid while taking Trogas?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Q: Can Prevacid cause hyperkalemia?
A: Prevacid (Trogas) belongs to a class of drugs called proton pump inhibitors (PPIs). PPIs decrease the amount of acid produced in the stomach. Prevacid is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as gastroesophageal reflux disease (GERD). Common side effects of Prevacid include headache, nausea, stomach pain, diarrhea, and constipation. A search of the prescribing information for Prevacid shows that increased blood levels of potassium or hyperkalemia can occur with Prevacid. Hyperkalemia is a condition caused by an abnormally high concentration of potassium in the blood. Potassium is a key element in contraction of muscles (including the heart) and for the functioning of many complicated proteins (enzymes). Potassium is found primarily in the skeletal muscle and bone, and participates with sodium to contribute to the normal flow between the body fluids and the cells of the body (homeostasis). The concentration of potassium in the body is regulated by the kidneys, and balance is maintained through excretion in urine. Sometimes hyperkalemia has no symptoms. Other times you may experience irregular heartbeat, fatigue, weakness, tingling, numbness, or other unusual sensations, paralysis, difficulty breathing, and nausea and vomiting. Sarah Lewis, PharmD
By Beth Schneider | Medically Reviewed by Ruthan White, PharmD
Latest Update: 2014-09-25 Copyright © 2014 Everyday Health Media, LLC
What brand names are available for Trogas?
Heartburn Relief 24 Hour, Heartburn Treatment 24 Hour, Prevacid 24HR, Prevacid, Prevacid SoluTab
Q: Does Prevacid cause urinary tract infections by taking away the good acid that prevents bacteria from growing?
A: A: Prevacid (Trogas) decreases the amount of acid produced in the stomach. Prevacid is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Its effects are produced in the stomach which is part of the digestive tract. The digestive tract consists esophagus, stomach, small intestine, large intestine, and rectum. Urinary tract infections (UTIs) happen when bacteria invade and begin to multiply in the organs of the urinary tract.