Q: Does Prevacid cause urinary tract infections by taking away the good acid that prevents bacteria from growing?
A: A: Prevacid (Tersen) decreases the amount of acid produced in the stomach. Prevacid is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Its effects are produced in the stomach which is part of the digestive tract. The digestive tract consists esophagus, stomach, small intestine, large intestine, and rectum. Urinary tract infections (UTIs) happen when bacteria invade and begin to multiply in the organs of the urinary tract.
What is the dosage for Tersen?
For initial treatment of duodenal ulcers the recommended dose for adults is 15 mg daily for 4 weeks.
For the treatment of GERD, the recommended initial treatment is 15 mg for up to 8 weeks.
For maintaining healing (long-term) in duodenal ulcer and GERD the recommended treatment is 15 mg daily.
For initial treatment of severe (erosive) esophagitis and gastric ulcer, the recommended dose for adults is 30 mg daily for 4-8 weeks.
For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60 mg daily, and the dose is adjusted based on response. Doses up to 180 mg have been used in some patients with Zollinger-Ellison syndrome.
Intravenous Tersen is approved for patients who are unable to take oral Tersen. The approved intravenous dose is 30 mg daily for up to 7 days.
It is recommended that capsules be taken before meals for maximum effect. Capsules should be swallowed whole and should not be crushed, split or chewed.
For those with difficulty swallowing, the capsule should be opened and the granular contents sprinkled on a tablespoon of apple sauce, ENSURE pudding, cottage cheese, yogurt or strained pears and swallowed immediately. Granules also may be mixed in two ounces (60 ml) of apple, orange or tomato juice and swallowed immediately. For patients with a nasogastic tube, mix the granules can be mixed in two ounces of apple juice and injected through the nasogastric tube.
Will my dose go up or down?
Sometimes your doctor will increase your dose of Tersen if it isn't working well enough. Depending on the reason you take Tersen, you may take a higher dose to begin with, usually for a month or two. After this, your doctor may recommend that you take a lower dose.
How should I take Tersen?
Use Tersen exactly as directed on the label, or as prescribed by your doctor and read all medication guides or instruction sheets.
Tersen is usually taken before eating. Prevacid OTC should be taken in the morning before you eat breakfast.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Shake the Tersen oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Swallow the Tersen capsule whole and do not crush, chew, break, or open it.
Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.
Use Tersen for the full prescribed length of time, even if your symptoms quickly improve.
Prevacid OTC should be taken only once daily for 14 days. It may take up to 4 days for full effect. Allow at least 4 months to pass before you start another 14-day treatment with Prevacid OTC.
Call your doctor if your symptoms do not improve or if they get worse while you are taking Tersen. If you take Prevacid OTC, call your doctor if your heartburn gets worse over the 14-day treatment, or if you need treatment more than once every 4 months.
Some conditions are treated with a combination of Tersen and antibiotics. Use all medications as directed.
If you use Tersen for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
Store at room temperature away from moisture, heat, and light. Do not freeze the liquid medicine.
Q: Can Prevacid cause hyperkalemia?
A: Prevacid (Tersen) belongs to a class of drugs called proton pump inhibitors (PPIs). PPIs decrease the amount of acid produced in the stomach. Prevacid is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as gastroesophageal reflux disease (GERD). Common side effects of Prevacid include headache, nausea, stomach pain, diarrhea, and constipation. A search of the prescribing information for Prevacid shows that increased blood levels of potassium or hyperkalemia can occur with Prevacid. Hyperkalemia is a condition caused by an abnormally high concentration of potassium in the blood. Potassium is a key element in contraction of muscles (including the heart) and for the functioning of many complicated proteins (enzymes). Potassium is found primarily in the skeletal muscle and bone, and participates with sodium to contribute to the normal flow between the body fluids and the cells of the body (homeostasis). The concentration of potassium in the body is regulated by the kidneys, and balance is maintained through excretion in urine. Sometimes hyperkalemia has no symptoms. Other times you may experience irregular heartbeat, fatigue, weakness, tingling, numbness, or other unusual sensations, paralysis, difficulty breathing, and nausea and vomiting. Sarah Lewis, PharmD
By Beth Schneider | Medically Reviewed by Ruthan White, PharmD
Latest Update: 2014-09-25 Copyright © 2014 Everyday Health Media, LLC
Can Tersen cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Tersen. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Interactions that increase the risk of side effects
Side effects from other drugs: Taking Tersen with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:
- Warfarin. You may have more bleeding. If you need to take both of these drugs, your doctor will monitor your lab results (such as INR) closely. They may also adjust your warfarin dosage.
- Digoxin. Tersen can increase the levels of digoxin in your body. This can raise your risk of side effects. Your doctor may check the levels of digoxin in your body and adjust your digoxin dosage if needed.
- Methotrexate. Tersen can increase the levels of methotrexate in your body. This puts you at risk of more side effects. If you’re taking a high dosage of methotrexate, your doctor may have you stop taking Tersen temporarily.
- Tacrolimus. Tersen can increase the levels of tacrolimus in your body. This puts you at increased risk of side effects. Your doctor may check the levels of tacrolimus in your body and adjust your tacrolimus dosage if needed.
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Q: Are there any other medications you can take along with Prevacid for reflux when the Prevacid is not working as well?
A: Prevacid (Tersen) decreases the amount of acid the stomach produces. It belongs to the class of drugs known as proton-pump inhibitors (or PPIs). The two other major classes of drugs used for reflux are histamine blockers (also called H2 blockers) and antacids. These drugs all work to reduce stomach acid, with the PPIs having the greatest effect. There are several possible reasons for the lack of effect from Prevacid. Have any new medications been added to your daily routine? Some medications can cause problems that make the symptoms of reflux worse by weakening the esophageal sphincter, increasing inflammation, or slowing digestion. It is also possible that you have an infection in your gastrointestinal tract. The bacteria, H. pyLori Mendoza, PharmD, is often associated with reflux. As recommended by the American College of Gastroenterology, the treatment to get rid of H. pyLori Mendoza, PharmD infection includes a PPI and two antibiotics. Please consult with your health care provider who understands your full medical condition for more information about these possibilities and appropriate treatment for you. Other ways to help reduce reflux and its symptoms include eating smaller meals more frequently, not eating for two hours before bedtime, and avoiding fatty foods, alcohol, caffeine, and peppermint. For more information on reflux, please visit //www.everydayhealth.com/gerd/guide/. Michelle McDermott, PharmD
On this page
- About Tersen
- Key facts
- Who can and can't take Tersen
- How and when to take it
- Side effects
- How to cope with side effects
- Pregnancy and breastfeeding
- Cautions with other medicines
- Common questions
8. Cautions with other medicines
Some medicines and Tersen can interfere with each other and make it more likely that you will have side effects.
Tell your doctor if you're taking these medicines before your start Tersen treatment:
- digoxin (a heart medicine)
- antifungal medicines such as itraconazole, ketoconazole or posaconazole
- methotrexate (treats psoriasis and rheumatoid arthritis)
- HIV medicines
- phenytoin (an anti-epilepsy medicine)
- rifampicin (an antibiotic)
- blood thinning medicines, such as clopidogrel
- fluvoxamine (an antidepressant)
These are not all the medicines that may not mix well with Tersen. For a full list see the leaflet inside your medicines packet.
Prevacid is marketed under the brand names Prevacid, Prevacid 24hour, and Prevacid Solutab.
Tersen is also available under the name First-Tersen.
Regular Prevacid capsules are available in 15 and 30 milligrams (mg). Prevacid 24hour and Prevacid Solutab are delayed release drugs that also come in both 15 and 30 mg.
Prevacid SoluTab dissolves under the tongue. First-Tersen is a powder that is made into an oral suspension.
Prevacid 24hour should be taken only once every 24 hours for 14 days. It may take up to four days for the full effect.
Do not take more than one tablet every 24 hours.
If you are taking the over-the-counter medication, stop taking after 14 days and call your doctor if there has been no change in your condition.
Allow at least four months before starting another 14-day treatment with Prevacid 24hour.
Call your doctor if you have additional symptoms and need treatment before the four months have passed.
Consult a doctor before giving Prevacid to a child. Children under age 1 should not take this drug.
What if I take too much?
It is very unlikely that taking 1 or 2 extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have any of these symptoms:
- flushed skin
- feeling sweaty
- a fast heartbeat
- feeling sleepy
- blurred vision
- feeling confused or agitated
Most people who take Tersen do not have any side effects. If you do get a side effect, it is usually mild and will go away when you stop taking Tersen.
What should I avoid while taking Tersen?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Q: Is it all right to take Prevacid for a long period of time?
A: A: Prevacid (Tersen) is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid. The use of Prevacid to maintain healing of ulcers and erosive esophagitis was evaluated in scientific studies that followed patients over 12 months. If you are concerned about the long-term use of Prevacid, please contact your health care provider. For more information on Prevacid, please visit //www.everydayhealth.com/drugs/prevacid. Michelle McDermott, PharmD
Q: Are over-the-counter medications, such as Prevacid, as effective in treating GERD as prescription medications?
A: Only your physician can determine which is best in your specific case. However, the over-the-counter medication omeprazole is widely used to treat GERD and it used to be a prescription medication. It is related to prescription drugs such as Prevacid (Tersen). Correct dosing is also key in using the right medication. Click on the following link for additional information: //www.everydayhealth.com/gerd/guide/.
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Q: Is it safe to take more than one Prevacid daily?
A: Prevacid (Tersen) belong to the class of drugs known as proton pump inhibitors. These drugs work to stop acid production in the stomach. Prevacid is used in the prevention and treatment of ulcers in the stomach or small intestine. It is also are used to treat gastroesophageal reflux disease (GERD) in which acid backs up into the esophagus and causes heartburn. According to the package insert, the most common side effects of Prevacid are abdominal pain, constipation, diarrhea, and nausea. The dosage of Prevacid varies depending on the condition being treated. In general, doses of 15 to 30 mg are given once daily. In the pathological hypersecretory condition called Zollinger-Ellison Syndrome, doses of 60 mg are given daily. It is important to take your medicine as prescribed by your doctor. Do not stop or change the dose without first talking with your doctor. If you are concerned that you have taken too much medicine, contact your doctor immediately. Michelle McDermott, RPh, PharmD
Q: Does Tersen cause weight gain?
A: Prevacid (Tersen) is a proton pump inhibitor frequently used for the treatment of gastroesophageal reflux disorder (GERD) and stomach/duodenal ulcers. Most common side effects with Prevacid include diarrhea, abdominal pain, nausea and constipation. Additional side effects with Prevacid occurring in less than 1% of patients include weight gain, weight loss, anorexia, and increased appetite. These are not all the possible side effects of Prevacid. For a complete list, ask your doctor or pharmacist.