Before taking this medicine
You should not use Sedural if you are allergic to it, or if you have kidney disease.
To make sure Sedural is safe for you, tell your doctor if you have:
a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
FDA pregnancy category B. Sedural is not expected to harm an unborn baby. Do not use Sedural without a doctor's advice if you are pregnant.
It is not known whether Sedural passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.
What are the uses for Sedural-oral?
Sedural is used to provide relief of symptoms associated with lower urinary tract infections including urinary burning, pain, urgency, and frequency among others.
Treatment for UTI Symptoms
AZO Urinary Pain Relief ® and AZO Urinary Pain Relief ® Maximum Strength don’t just treat your urinary pain like any ordinary pain. They work to relieve your UTI symptoms fast, so you don’t have to miss a thing! 1 There’s just one catch—one of the key ingredients in AZO Urinary Pain Relief ® , responsible for relieving your UTI symptoms so quickly, is also known to dye urine and fabrics orange. 2 This key ingredient is called Sedural hydrochloride.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Sedural.
Sedural can interfere with laboratory tests, including urine tests for glucose (sugar) and ketones. If you have diabetes, you should use Clinitest rather than Tes-Tape or Clinistix to test your urine for sugar. Urine tests for ketones (Acetest and Ketostix) may give false results. Before you have any tests, tell the laboratory personnel and doctor that you take this medication.
Sedural stains clothing and contact lenses. Avoid wearing contact lenses while taking this medicine.
Do not let anyone else take your medication. Your prescription is probably not refillable.
If you still have symptoms after you finish the Sedural, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
What is phenazopyr >
Sedural is a pain reliever that affects the lower part of your urinary tract (bladder and urethra).
Sedural is used to treat urinary symptoms such as pain or burning, increased urination, and increased urge to urinate. These symptoms can be caused by infection, injury, surgery, catheter, or other conditions that irritate the bladder.
Sedural will treat urinary symptoms, but this medication will not treat a urinary tract infection.. Take any antibiotic that your doctor prescribes to treat an infection.
Sedural may also be used for purposes not listed in this medication guide.
22.214.171.124.1 Diffusivity may reveal aggregation
The two right-most columns in Table 4 are expected to be the experimental diffusivity. The value averages to 7.5×10 −6 cm 2 s −1 . The theoretically expected diffusivity is 8.6×10 −6 cm 2 s −1 for a monomer and 6.3×10 −6 cm 2 s −1 for a dimer, using a formula related to molecular weight. 1 Figure 4c indicates that Sedural forms a cationic aggregate in low pH solution. In Table 4 , at pH 1.1, the Sedural hydrochloride pellet experiment shows an apparent diffusivity of 6.5×10 −6 cm 2 s −1 . This suggests the possibility that the pH 1.1 dissolution data are indicative of some aggregation of the cationic species, perhaps a dimer – a new perspective on the interesting 1985 study.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Take Sedural after meals.
Drink plenty of liquids while you are taking Sedural.
Sedural will most likely darken the color of your urine to an orange or red color. This is a normal effect and is not harmful. Darkened urine may also cause stains to your underwear that may be permanent.
Sedural can also permanently stain soft contact lenses, and you should not wear them while taking this medicine.
Do not use Sedural for longer than 2 days unless your doctor has told you to.
This medication can cause unusual results with urine tests. Tell any doctor who treats you that you are using Sedural.
Store at room temperature away from moisture and heat.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Copyright 1996-2019 Cerner Multum, Inc.
Latest Update: 11/9/2018, Version: 3.05
What Is Pyr >
Pyridium is the brand name for Sedural, a medication used to relieve symptoms caused by irritation of the urinary tract, such as pain, burning, and the feeling of needing to urinate urgently or frequently.
It can also be used to treat other discomforts in the lower urinary tract caused by trauma, surgery, endoscopic procedures, or catheters.
You should not take Pyridium for more than two days. There is no evidence that the combined effect of Pyridium and an antibacterial provides greater benefit than administration of the antibacterial alone after that two-day time period.
Pyridium was discovered by Bernhard Joos, the founder of Cilag.
Pyridium® (Sedural Hydrochloride) is light or dark red to dark violet, odorless, slightly bitter, crystalline powder. It has a specific local analgesic effect in the urinary tract, promptly relieving burning and pain. It has the following structural formula:
Pyridium (Sedural HCl Tablets, USP) contains the following inactive ingredients: carnauba wax, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone and pregelatinized starch.
How is this medicine (Sedural) best taken?
Use Sedural as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take Sedural by mouth with or after food.
- Take with a full glass of water.
What do I do if I miss a dose?
- Tell all of your health care providers that you take Sedural. This includes your doctors, nurses, pharmacists, and dentists.
- This medicine is not to be used instead of an antibiotic. It will not cure a bladder infection.
- This medicine may stain clothing or fabric.
- Protect clothing and fabrics from staining.
- This medicine may stain contact lenses.
- Do not wear contact lenses while using Sedural.
- This medicine may change the color of urine or stools to an orange or red color. This is normal and not harmful.
- If you have G6PD deficiency, talk with healthcare provider.
- Do not take Sedural for longer than you were told by your doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Sedural.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Sedural while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.