Romatidine capsules

Romatidine

  • Active Ingredient: Ranitidine
  • 300 mg, 150 mg
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What is Romatidine?

The active ingredient of Romatidine brand is ranitidine. Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces. The empirical formula is C13H22N4O3S.HCl, representing a molecular weight of 350.87. Ranitidine HCl USP is a white to pale yellow crystalline powder that is soluble in water. It has a slightly bitter taste and sulfur-like odor. Each Ranitidine tablets, USP 150 mg for oral administration contains 168 mg of Ranitidine HCl USP equivalent to 150 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red. Each Ranitidine tablets, USP 300 mg for oral administration contains 336 mg of Ranitidine HCl USP equivalent to 300 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red.

Used for

Romatidine is used to treat diseases such as: Cutaneous Mastocytosis, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Eczema, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis, Urticaria, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Romatidine include: ; ; ; ; ; .

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What is ranit >

Romatidine belongs to a group of drugs called histamine-2 blockers. It works by reducing the amount of acid your stomach produces.

Romatidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.

Romatidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

What should I discuss with my healthcare provider before using Romatidine?

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Do not use this medication if you are allergic to Romatidine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • kidney disease;
  • liver disease; or
  • porphyria.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Romatidine passes into breast milk. Do not take Romatidine without telling your doctor if you are breast-feeding a baby.

Using Romatidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.

The Romatidine effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of Romatidine if you have phenylketonuria (PKU).

How should I take Romatidine?

Take Romatidine exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Do not crush, chew, or break an effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.

Allow the effervescent tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.

Romatidine granules should be mixed with 6 to 8 ounces of water before drinking.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 8 weeks before your ulcer heals. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Romatidine.

Store at room temperature away from moisture, heat, and light.

Certain prescription and over-the-counter (OTC) medications that contain the ingredient ranit >FDA site .

Romatidine is a drug that’s available in a prescription version and an over-the-counter version. This article only addresses the prescription version. Prescription Romatidine comes as an oral tablet, oral capsule, or oral syrup. It also comes as an injectable solution.

Romatidine oral tablet is available as the brand-name drug Zantac. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

8. Cautions with other medicines

Some medicines can interfere with Romatidine and make you more likely to have side effects.

Tell your doctor if you're taking these medicines before you start taking Romatidine:

  • anti-fungal medicines such as itraconazole, ketoconazole or posaconazole
  • any medicine used to treat cancer
  • HIV medicines

These are not all the medicines that may not mix well with Romatidine. For a full list see the leaflet inside your medicines packet.

What to do about:

  • stomach pains - try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help. If you are in a lot of pain, speak to your pharmacist or doctor.
  • constipation - eat more high-fibre foods such as fresh fruit and vegetables and cereals, and drink plenty of water. Try to exercise, for example, by going for a daily walk or run. If this doesn't help, talk to your pharmacist or doctor.
  • feeling sick - it may help if you don't eat rich or spicy food while you're taking Romatidine.

What other drugs will affect Romatidine?

Before taking Romatidine, tell your doctor if you are taking triazolam (Halcion). You may not be able to use Romatidine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can interact with Romatidine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Q: Is Zantac okay to take in late pregnancy? I'm 32 weeks pregnant and can't live without them. I'm taking about 2 per day.

A: For stomach acid during pregnancy, Zantac (Romatidine) is a category "B." In pregnancy, there are only 1 or 2 "perfect" drugs that are category "A," so if you need medication, you will probably be prescribed drugs that are in categories "B" or "C." The drugs that should be avoided are in catagories "D" and "X" because they can cause harmful effects. However, you should always consult with your doctor before taking any medication. You can also find helpful information on pregnancy at http://www.whattoexpect.com/pregnancy/week-by-week/landing.aspx. Patti Brown, PharmD

PATIENT INFORMATION

Allergy alert: Do not use if you are allergic to Romatidine or other acid reducers

Generic Name: Romatidine (ra NI ti deen)Brand Names: Zantac

Medically reviewed by Sanjai Sinha, MD Last updated on Dec 9, 2019.

For the treatment of High Blood Pressure purchase Veroxil over the counter tablets Blood Pressure

Important

Supplies of Romatidine are currently very limited. This is due to a possible risk with the ingredients.

Try to speak to your doctor before your Romatidine runs out. There are similar medicines they can prescribe for you if you still need it. In the meantime, keep taking your medicine as usual.

If you have any concerns, speak to your pharmacist or doctor.

Romatidine reduces the amount of acid your stomach makes.

It's used for indigestion and heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) - this is when you keep getting acid reflux. Romatidine is also taken to prevent and treat stomach ulcers.

Sometimes, Romatidine is taken for a rare illness caused by a tumour in the pancreas or gut called Zollinger-Ellison syndrome.

Romatidine comes as tablets, soluble (dispersible) tablets that dissolve in water to make a drink, or as a liquid that you drink.

All types of Romatidine are available on prescription. You can also buy the lowest strength 75mg tablets from pharmacies and supermarkets.

Studies pointing to risk date to 1980s

In 2016, Stanford University researchers tested urine samples of 10 people who took a 150-milligram tablet of Zantac and found NDMA levels far greater than the FDA's daily limits.

William Mitch is a Stanford University professor of civil and environmental engineering who studies wastewater converted to drinking water. He said his Zantac-urine study was a "chance finding from a peripheral field" after a study on potential NDMA contamination in drinking water.

He said it should be followed by a more robust study using the FDA's testing methods.

"The challenge is there's so much concern about cancer risk. Could you get approval from someone to eat a Zantac and collect the urine sample?" Mitch said, noting such a request would be odd and ethically challenging, given the drug has a known carcinogen and remains on the market.

Lior Braunstein, a Memorial Sloan Kettering oncologist and researcher, is studying Romatidine and cancer risk. He does not want to discuss the study until the findings are published in a peer-reviewed journal, according to Caitlin Hool, a hospital spokeswoman.

Light said studies conducted in the 1980s raised concern about potential safety risks. In a citizen petition to the FDA, Valisure said Zantac's originator, Glaxo Research Group, conducted its own study in 1987 "after numerous studies raised concerns" about Romatidine.

The Glaxo study examined stomach contents of people who took the drug. It found people had no significant increase in nitrosamines such as NDMA within 24 hours of taking Romatidine.

Light said the study's testing methods were less accurate and researchers discarded stomach samples that contained Romatidine. Without those samples, researchers would not find NDMA or nitrosamines that form as a result of taking the drug, Light said.

Light said the Stanford study and his lab's own analysis shows the potential health risk for people who took the drug.

"The negative effect of exposure to this drug and its formation of NDMA is something that has created a huge public health problem," he said, "and we’re going to be dealing with it going forward."


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