Pantosec tablets


  • Active Ingredient: Pantoprazole
  • 40 mg, 20 mg
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What is Pantosec?

The active ingredient of Pantosec brand is pantoprazole. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole sodium USP is a white to off-white powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium USP is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5 and approximately 220 hours at pH 7.8. Pantoprazole sodium USP is supplied as a delayed-release tablet, available in two strengths 20 mg Pantoprazole (equivalent to 22.56 mg of Pantoprazole sodium USP) and 40 mg Pantoprazole (equivalent to 45.1 mg of Pantoprazole sodium USP). Pantoprazole sodium delayed-release tablets, USP contain the following inactive ingredients: calcium stearate, crospovidone, ferric oxide, hydroxypropyl cellulose, hypromellose, mannitol, methacrylic acid copolymer dispersion, sodium carbonate, and triethyl citrate. The tablets are imprinted with brown ink containing ammonium hydroxide, iron oxide black, iron oxide red, iron oxide yellow, isopropyl alcohol, N-butyl alcohol, propylene glycol, and shellac glaze in ethanol. Pantoprazole sodium delayed-release tablets (40 mg and 20 mg) complies USP dissolution test 3.

Used for

Pantosec is used to treat diseases such as: Barrett's Esophagus, Dumping Syndrome, Duodenal Ulcer, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Peptic Ulcer, Stomach Ulcer, Stress Ulcer Prophylaxis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Pantosec include: light-colored stools; unexplained bleeding or bruising; constipation; Abdominal or stomach pain; fruit-like breath odor; cough; passing gas.

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Some people taking warfarin with Pantosec can experience increases in INR and prothrombin time (PT). This can lead to an increased risk of severe bleeding. If you take these drugs together, your doctor should monitor you for increases in INR and PT.

Dictionary Entries near Pantosec

Cite this Entry

“Pantosec.” The Medical Dictionary, Merriam-Webster Inc., Accessed 27 December 2019.

Comments on Pantosec

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Drugs affected by stomach pH

Pantosec affects stomach acid levels. As a result, it can reduce your body’s absorption of certain drugs that are sensitive to the effects of decreased stomach acid. This effect can make these drugs less effective.

Examples of these drugs include:

  • ketoconazole
  • ampicillin
  • atazanavir
  • iron salts
  • erlotinib
  • mycophenolate mofetil

Generic Name: Pantosec (oral/injection) (pan TOE pra zole)Brand Names: Protonix

Medically reviewed by Last updated on Sep 13, 2018.

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Proton pump inhibitors such as Pantosec stop cells in the lining of the stomach from producing too much acid. This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn. Pantosec is also given as one part of a treatment to get rid of Helicobacter pylori, a bacterium found in the stomach, which can cause ulcers.

Pantosec is available on prescription. You can also buy short courses of Pantosec at a pharmacy for the treatment of reflux symptoms (such as heartburn) in adults.

Storage And Handling

PROTONIX (Pantosec sodium) Delayed-Release Tablets are supplied as yellow, oval biconvex delayed-release tablets imprinted with PROTONIX (brown ink) on one side containing 40 mg Pantosec and are available as follows:

PROTONIX (Pantosec sodium) Delayed-Release Tablets are supplied as yellow oval biconvex delayed-release tablets imprinted with P20 (brown ink) on one side containing 20 mg Pantosec and are available as follows:

PROTONIX (Pantosec sodium) For Delayed-Release Oral Suspension contains pale yellowish to dark brownish, enteric-coated granules containing 40 mg Pantosec in a 40 mg unit-dose packet and are available as follows:

  • NDC 0008-0844-02, unit-dose carton of 30

How it works

Pantosec belongs to a class of drugs called proton pump inhibitors. It works to shut off the acid-pumping cells in your stomach. It reduces the amount of stomach acid and helps to reduce painful symptoms related to conditions such as GERD.

Pantosec oral tablet does not cause drowsiness. However, it can cause other side effects.

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