Pansec tablets


  • Active Ingredient: Pantoprazole
  • 40 mg, 20 mg
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What is Pansec?

The active ingredient of Pansec brand is pantoprazole. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole sodium USP is a white to off-white powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium USP is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5 and approximately 220 hours at pH 7.8. Pantoprazole sodium USP is supplied as a delayed-release tablet, available in two strengths 20 mg Pantoprazole (equivalent to 22.56 mg of Pantoprazole sodium USP) and 40 mg Pantoprazole (equivalent to 45.1 mg of Pantoprazole sodium USP). Pantoprazole sodium delayed-release tablets, USP contain the following inactive ingredients: calcium stearate, crospovidone, ferric oxide, hydroxypropyl cellulose, hypromellose, mannitol, methacrylic acid copolymer dispersion, sodium carbonate, and triethyl citrate. The tablets are imprinted with brown ink containing ammonium hydroxide, iron oxide black, iron oxide red, iron oxide yellow, isopropyl alcohol, N-butyl alcohol, propylene glycol, and shellac glaze in ethanol. Pantoprazole sodium delayed-release tablets (40 mg and 20 mg) complies USP dissolution test 3.

Used for

Pansec is used to treat diseases such as: Barrett's Esophagus, Dumping Syndrome, Duodenal Ulcer, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Peptic Ulcer, Stomach Ulcer, Stress Ulcer Prophylaxis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Pansec include: fast heartbeat; general feeling of tiredness or weakness; indigestion; bloody, black, or tarry stools; vomiting of blood.

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Pansec Dosage

Pansec is supplied as a granule for delayed-release oral suspension, available in one strength (40 mg), and as a delayed-release tablet, available in two strengths (20 mg and 40 mg).

It's also available in an intravenous (IV) solution for hospital use.

Typically, your doctor will prescribe 40 mg daily for four to eight weeks of treatment. The medication should be taken around the same time each day.

Take Pansec for the full prescribed length of time as your symptoms may improve before your condition is completely treated.

What is the dosage for Protonix?

  • Pansec used for treatment GERD and healing erosive esophagitis the recommended dose for adults is 40 mg daily for 4-8 weeks.
  • The dose for treating Zollinger-Ellison syndrome is 40 mg twice daily.
  • It generally is recommended that tablets be taken approximately 30 minutes prior to meals for maximal effectiveness. Tablets should be swallowed whole and should not be crushed, split or chewed.

Cutaneous And Systemic Lupus Erythematosus

Cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) have been reported in patients taking PPIs, including Pansec sodium. These events have occurred as both new onset and an exacerbation of existing autoimmune disease. The majority of PPIinduced lupus erythematous cases were CLE.

The most common form of CLE reported in patients treated with PPIs was subacute CLE (SCLE) and occurred within weeks to years after continuous drug therapy in patients ranging from infants to the elderly. Generally, histological findings were observed without organ involvement.

Systemic lupus erythematosus (SLE) is less commonly reported than CLE in patients receiving PPIs. PPI associated SLE is usually milder than non-drug induced SLE. Onset of SLE typically occurred within days to years after initiating treatment primarily in patients ranging from young adults to the elderly. The majority of patients presented with rash; however, arthralgia and cytopenia were also reported.

Avoid administration of PPIs for longer than medically indicated. If signs or symptoms consistent with CLE or SLE are noted in patients receiving PROTONIX, discontinue the drug and refer the patient to the appropriate specialist for evaluation. Most patients improve with discontinuation of the PPI alone in 4 to 12 weeks. Serological testing (e.g. ANA) may be positive and elevated serological test results may take longer to resolve than clinical manifestations.

Bacterial infections

Several studies have linked the use of Pansec with C. difficile diarrhea. This infective diarrhea can be fatal, particularly among older adults.

Doctors should prescribe the lowest effective dosage for the shortest time possible to prevent this infection.

Pansec to reduce stomach ac >About Pansec
  • Before taking Pansec
  • How to take Pansec
  • Getting the most from your treatment
  • Can Pansec cause problems?
  • How to store Pansec
  • Important information about all medicines
  • What is Pansec (Protonix, Protonix IV)?

    Pansec is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

    Pansec is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pansec is usually given for up to 8 weeks at a time while your esophagus heals.

    Pansec is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.

    Pansec is not for immediate relief of heartburn.

    Pansec may also be used for purposes not listed in this medication guide.

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