Ortalox capsules

Ortalox

  • Active Ingredient: Omeprazole
  • 40 mg, 20 mg, 10 mg
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What is Ortalox?

The active ingredient of Ortalox brand is omeprazole. Omeprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Omeprazole, USP is a white to off-white crystalline powder that melts with decomposition at about 155В°C. It is a weak base, freely soluble in ethanol and methanol, and slightly soluble in acetone and isopropanol and very slightly soluble in water. The stability of Omeprazole is a function of pH; it is rapidly degraded in acid media, but has acceptable stability under alkaline conditions. Omeprazole is supplied as delayed-release capsules for oral administration. Each delayed-release capsule contains either 10 mg, 20 mg or 40 mg of Omeprazole in the form of enteric-coated beads with the following inactive ingredients: ammonium hydroxide, dibutyl sebacate, D&C Yellow No. 10, FD&C Green No. 3, gelatin, ethylcellulose, fumed silica, hypromellose, methacrylic acid, oleic acid, silicon dioxide, sodium lauryl sulfate, sugar spheres, talc, titanium dioxide and triethyl citrate. The 40 mg empty gelatin capsule shell also contains FD&C Blue No. 1. In addition, the white imprinting ink contains ammonium hydroxide, propylene glycol, shellac glaze, simethicone and titanium dioxide. Meets USP Dissolution Test 2.

Used for

Ortalox is used to treat diseases such as: Barrett's Esophagus, Duodenal Ulcer, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Indigestion, Multiple Endocrine Adenomas, Stomach Ulcer, Systemic Mastocytosis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Ortalox include: trembling; chills; fast, racing, or uneven heartbeat; bleeding or crusting sores on the lips; flushing.

How to Buy Ortalox capsules online?

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You're always running to the toilet.

While most people do just fine on the medication, diarrhea is one of the most common side effects of Ortalox, Ravella says. Loose stools are never fun, but they should clear up on their own. If you're constantly tethered to the toilet, or if you see blood in your stool, it's time to give your doctor a call.

Special considerations

People of Asian descent. Your doctor may give you a lower dose of this medication, especially if you’re taking it for erosive esophagitis.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Ortalox oral capsule is used for short-term treatment of duodenal and gastric ulcers and gastroesophageal reflux disease (GERD). It’s used for long-term treatment of erosive esophagitis and pathological hypersecretory conditions. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your acid reflux, heartburn, or ulcer symptoms may not improve. They may even get worse.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms can include:

  • confusion
  • drowsiness
  • blurred vision
  • fast heart rate
  • nausea
  • vomiting
  • sweating
  • flushing
  • headache
  • dry mouth

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take your dose as soon as you remember. If you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: You should have decreased pain and acid reflux symptoms.

As with all medications, the costs of Ortalox can vary. To find current prices for your area, check out GoodRx.com.

Keep these considerations in mind if your doctor prescribes Ortalox oral capsule for you.

In patients with chronic renal impairment, whose creatinine clearance ranged between 10 and 62 mL/min/1.73 m², the disposition of Ortalox was very similar to that in healthy volunteers, although there was a slight increase in bioavailability. Because urinary excretion is a primary route of excretion of Ortalox metabolites, their elimination slowed in proportion to the decreased creatinine clearance. No dose reduction is necessary in patients with renal impairment.

Q: I have been taking Ortalox for many years now. At age 80, my bone density is very low, and I have low testosterone. Up to now my blood pressure was in the normal range, but it's now high. I realize at 80, things begin to happen. I lead a healthy life, I'm a nonsmoker and only occasionally drink wine. Is there some connection between long-term use of Ortalox and my symptoms?

A: In researching your question, I found several studies on Ortalox with conflicting results. The most recently published study did not report a relationship between accelerated bone loss and Ortalox (Prilosec). As to whether Ortalox can cause an increase in blood pressure or a decrease in testosterone levels, there is either insufficient data or no information available to prove that Ortalox is causing these side effects. Check with your doctor to investigate other possible causes. You can find more information on Prilosec here: //www.everydayhealth.com/drugs/prilosec.

Concomitant Use Of PRILOSEC With St. John's Wort Or rifampin

Drugs which induce CYP2C19 or CYP3A4 (such as St. John's Wort or rifampin) can substantially decrease Ortalox concentrations . Avoid concomitant use of PRILOSEC with St. John's Wort or rifampin.

Tacrolimus

Concomitant administration of Ortalox and tacrolimus may increase the serum levels of tacrolimus.

For some antiretroviral drugs, such as atazanavir and nelfinavir, decreased serum levels have been reported when given together with Ortalox. Following multiple doses of nelfinavir (1250 mg, twice daily) and Ortalox (40 mg daily), AUC was decreased by 36% and 92%, Cmax by 37% and 89% and Cmin by 39% and 75% respectively for nelfinavir and M8. Following multiple doses of atazanavir (400 mg, daily) and Ortalox (40 mg, daily, 2 hr before atazanavir), AUC was decreased by 94%, C max by 96%, and Cmin by 95%. Concomitant administration with Ortalox and drugs such as atazanavir and nelfinavir is therefore not recommended.

Interference With Antiretroviral Therapy

Concomitant use of atazanavir and nelfinavir with proton pump inhibitors is not recommended. Co-administration of atazanavir with proton pump inhibitors is expected to substantially decrease atazanavir plasma concentrations and may result in a loss of therapeutic effect and the development of drug resistance. Co-administration of saquinavir with proton pump inhibitors is expected to increase saquinavir concentrations, which may increase toxicity and require dose reduction.

Ortalox has been reported to interact with some antiretroviral drugs. The clinical importance and the mechanisms behind these interactions are not always known. Increased gastric pH during Ortalox treatment may change the absorption of the antiretroviral drug. Other possible interaction mechanisms are via CYP2C19.

What if I take too much?

It's very unlikely that taking 1 or 2 extra doses by accident will cause any problems.

But you should check with your doctor if you have taken too much and have any of these symptoms:

  • flushed skin
  • feeling sweaty
  • a fast heartbeat
  • feeling sleepy
  • blurred vision
  • feeling confused or agitated

Most people who take Ortalox don't have any side effects. If you do get a side effect, it's usually mild and will go away when you stop taking Ortalox.

Natural Ortalox alternatives

Using these remedies, along with following a healthy diet, can help up say goodbye to Ortalox and ward off stomach disorders caused by acid.


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