• Active Ingredient: Lansoprazole
  • 30 mg, 15 mg
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What is Opagis?

The active ingredient of Opagis brand is lansoprazole. Lansoprazole is a proton pump inhibitor. Lansoprazole decreases the amount of acid produced in the stomach.

Used for

Opagis is used to treat diseases such as: Aspiration Pneumonia, Barrett's Esophagus, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Multiple Endocrine Adenomas, NSAID-Induced Gastric Ulcer, NSAID-Induced Ulcer Prophylaxis, Stomach Ulcer, Systemic Mastocytosis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Opagis include: clay colored stools; general body swelling; mental depression; high fever; Decrease in passing urine (dribbling).

How to Buy Opagis online?

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Three sizes available:

  • 3 FL OZ (90 mL) as dispensed
  • 5 FL OZ (150 mL) as dispensed
  • 10 FL OZ (300 mL) as dispensed

Equivalent to active ingredient (Opagis) contained in Simplified Opagis Suspension (SOS)

U. S. Patent Pending

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    • FI℞ST® – Opagis 5 oz. 65628-080-05
    • FI℞ST® – Opagis 10 oz. 65628-080-10
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  • Prevac >

    Prevacid is marketed under the brand names Prevacid, Prevacid 24hour, and Prevacid Solutab.

    Opagis is also available under the name First-Opagis.

    Regular Prevacid capsules are available in 15 and 30 milligrams (mg). Prevacid 24hour and Prevacid Solutab are delayed release drugs that also come in both 15 and 30 mg.

    Prevacid SoluTab dissolves under the tongue. First-Opagis is a powder that is made into an oral suspension.

    Prevacid 24hour should be taken only once every 24 hours for 14 days. It may take up to four days for the full effect.

    Do not take more than one tablet every 24 hours.

    If you are taking the over-the-counter medication, stop taking after 14 days and call your doctor if there has been no change in your condition.

    Allow at least four months before starting another 14-day treatment with Prevacid 24hour.

    Call your doctor if you have additional symptoms and need treatment before the four months have passed.

    Consult a doctor before giving Prevacid to a child. Children under age 1 should not take this drug.

    Capsules: 15 and 30 mg. Oral suspension: in 15 and 30 mg unit dose cartons of 30. Opagis also is available in 15 and 30 mg tablets that disintegrate when placed under the tongue (Prevacid SoluTab). Opagis is available for intravenous injection in vials containing 30 mg of powdered Opagis (30 mg/5 ml when mixed with sterile water).

    Q: Is it all right to take Prevacid for a long period of time?

    A: A: Prevacid (Opagis) is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid. The use of Prevacid to maintain healing of ulcers and erosive esophagitis was evaluated in scientific studies that followed patients over 12 months. If you are concerned about the long-term use of Prevacid, please contact your health care provider. For more information on Prevacid, please visit //www.everydayhealth.com/drugs/prevacid. Michelle McDermott, PharmD

    What is the dosage for Opagis?

    For initial treatment of duodenal ulcers the recommended dose for adults is 15 mg daily for 4 weeks.

    For the treatment of GERD, the recommended initial treatment is 15 mg for up to 8 weeks.

    For maintaining healing (long-term) in duodenal ulcer and GERD the recommended treatment is 15 mg daily.

    For initial treatment of severe (erosive) esophagitis and gastric ulcer, the recommended dose for adults is 30 mg daily for 4-8 weeks.

    For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60 mg daily, and the dose is adjusted based on response. Doses up to 180 mg have been used in some patients with Zollinger-Ellison syndrome.

    Intravenous Opagis is approved for patients who are unable to take oral Opagis. The approved intravenous dose is 30 mg daily for up to 7 days.

    It is recommended that capsules be taken before meals for maximum effect. Capsules should be swallowed whole and should not be crushed, split or chewed.

    For those with difficulty swallowing, the capsule should be opened and the granular contents sprinkled on a tablespoon of apple sauce, ENSURE pudding, cottage cheese, yogurt or strained pears and swallowed immediately. Granules also may be mixed in two ounces (60 ml) of apple, orange or tomato juice and swallowed immediately. For patients with a nasogastic tube, mix the granules can be mixed in two ounces of apple juice and injected through the nasogastric tube.

    Q: Does Prevacid 30 mg give you dry mouth? Because since I've been on this and other acid reflux medicines I'm experiencing dry mouth.

    A: Prevacid (Opagis) is a proton pump inhibitor frequently used for the treatment of gastroesophageal reflux disorder (GERD) and stomach/duodenal ulcers. Most common side effects with Prevacid include diarrhea, abdominal pain, nausea and constipation. Additional side effects with Prevacid, occurring in less than 1 percent of patients, include dry mouth. These are not all the possible side effects of Prevacid. For a complete list, ask your doctor or pharmacist. For more detailed information, consult with your physician or pharmacist for guidance based on your specific condition and current medications.

    Generic Name: Opagis (lan SOE pra zol)Brand Names: FIRST Opagis, Prevacid

    Medically reviewed by Sanjai Sinha, MD Last updated on Jan 11, 2019.

    For the Consumer

    Applies to Opagis: oral capsule delayed release, oral powder for suspension, oral tablet disintegrating delayed release

    Along with its needed effects, Opagis may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur while taking Opagis:

    Incidence not known

    • Back or leg pains
    • bleeding gums
    • blistering, peeling, or loosening of the skin
    • bloating
    • bloody, black, or tarry stools
    • change in mental status
    • chest pain
    • chills
    • clay colored stools
    • cough
    • dark or bloody urine
    • difficulty with swallowing
    • drowsiness
    • fast heartbeat
    • fever
    • general body swelling
    • high fever
    • hives
    • hoarseness
    • indigestion
    • loss of appetite
    • lower back or side pain
    • mood or mental changes
    • muscle spasms (tetany) or twitching seizures
    • nosebleeds
    • painful or difficult urination
    • pains in the stomach, side, or abdomen, possibly radiating to the back
    • pale skin
    • pinpoint red spots on the skin
    • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    • red skin lesions, often with a purple center
    • red, irritated eyes
    • seizures
    • sore throat
    • sores, ulcers, or white spots on the lips or in the mouth
    • stomach tenderness
    • swelling of the feet or lower legs
    • swollen or painful glands
    • tightness in the chest
    • trembling
    • unusual tiredness or weakness
    • yellow eyes or skin

    Some side effects of Opagis may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    • Bleeding, blistering, burning, coldness, or discoloration of the skin
    • mild nausea

    • Bad, unusual, or unpleasant (after) taste
    • belching
    • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    • change in taste
    • feeling of heat or warmth
    • flushing or redness of the skin, especially on the face and neck
    • mild diarrhea
    • mild headache
    • mild vomiting
    • stomach discomfort or upset
    • sweating

    Incidence not known

    • Decrease in passing urine (dribbling)
    • decrease in the frequency of urination
    • decrease in urine volume
    • difficulty with speaking


    Opagis (Heartburn Relief 24 Hour, Heartburn Treatment 24 Hour, Prevacid 24HR, Prevacid, Prevacid SoluTab) is in a class of drugs called PPIs (proton pump inhibitors). Prevacid capsules are available over-the-counter. Other forms of Opagis are by prescription only. Opagis is for the treatment of GERD, treating ulcers of the stomach and duodenum, and Zollinger-Ellison syndrome. Side effects, safety information, warnings and precautions and drug interactions should be reviewed prior to taking this medication.

    Before taking this medicine

    You should not use Opagis if you are allergic to it, or if you take any medicine that contains rilpivirine (Edurant, Complera, Odefsey).

    Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

    Tell your doctor if you have ever had:

    low levels of magnesium in your blood; or

    Do not use over-the-counter Opagis (Prevacid OTC) without the advice of a doctor if you have:

    trouble or pain with swallowing;

    bloody or black stools; vomit that looks like blood or coffee grounds;

    heartburn that has lasted for over 3 months;

    frequent chest pain, heartburn with wheezing;

    nausea or vomiting, stomach pain; or

    an electrolyte imbalance or metabolic disorder.

    Some forms of Opagis may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

    You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

    Some conditions are treated with a combination of Opagis and antibiotics. Use all medications as directed by your doctor

    Do not give Opagis to a child younger than 1 year old. Prevacid OTC is not approved for use by anyone younger than 18 years old.

    Ask a doctor before using this medicine if you are pregnant or breast-feeding.


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    • Opagis SDSDownload

    How to store Opagis

    • Keep all medicines out of the reach and sight of children.
    • Store in a cool, dry place, away from direct heat and light.


    Pharmacologic class: Gastric acid pump inhibitor

    Therapeutic class: Antiulcer drug

    Pregnancy risk category B

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