Dosage Forms And Strengths
PRILOSEC Delayed-Release Capsules, 10 mg, are opaque, hard gelatin, apricot and amethyst colored capsules, coded 606 on cap and PRILOSEC 10 on the body.
PRILOSEC Delayed-Release Capsules, 20 mg, are opaque, hard gelatin, amethyst colored capsules, coded 742 on cap and PRILOSEC 20 on the body.
PRILOSEC Delayed-Release Capsules, 40 mg, are opaque, hard gelatin, apricot and amethyst colored capsules, coded 743 on cap and PRILOSEC 40 on the body.
PRILOSEC For Delayed-Release Oral Suspension, 2.5 mg or 10 mg, is supplied as a unit dose packet containing a fine yellow powder, consisting of white to brownish Omeran granules and pale yellow inactive granules.
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with Omeran.
Omeran belongs to the proton pump inhibitor (PPI) class of medications. Doctors prescribe Omeran to reduce stomach acid to help treat a variety of digestive conditions.
People can also use over-the-counter (OTC) Omeran to relieve heartburn or acid reflux.
Although most people tolerate Omeran well, there are certain risks when people use it for a long period of time.
In this article, we review the uses, side effects, and drug interactions of Omeran.
Q: What are the risks of taking Prilosec?
A: Prilosec (Omeran) is in a class of drugs called proton pump inhibitors. Prescription Prilosec is used to treat ulcers (sores in the lining of the stomach). In combination with other medications, Prilosec is used to eliminate H. pylori (a bacterium that causes ulcers); and thus prevent new ulcers from being formed in patients who have or have had ulcers of the small intestine. Prilosec is also used to treat gastroesophageal reflux disease (GERD) (a condition that is a result of stomach acid flowing backwards into the esophagus -- causing heartburn and damage); to heal erosive esophagitis (inflammation and damage to the esophagus lining); and to treat conditions in which the stomach makes too much acid. Over-the-counter Prilosec is used to treat heartburn that happens frequently -- at least 2 days per week. Prilosec works be reducing acid production in the stomach. The most common side effects with Prilosec are: headache, abdominal pain, nausea, diarrhea, vomiting, and excessive gas. Allergic reaction, which can occur with most medications, is a serious side effect with Prilosec. People should seek emergency medical help if they experience hives; trouble breathing; or swelling of the face, lips, tongue, or throat while taking Prilosec. Prilosec is a benzimidazole-type medication. People who are allergic to Omeran or other benzimidazole medication, like Albenza (albendazole) or Vermox (mebendazole) should not take Prilosec. Atrophic gastritis has been reported in people treated long-term with Prilosec. Atrophic gastritis is a condition where the normal glands of the stomach are decreased or absent; inflammation is present from attack by the immune system; and stomach cells are damaged. Atrophic gastritis is a precursor for stomach cancer. However, long-term use of proton pump inhibitors has not been proven to cause stomach cancer in humans. Prilosec interacts with certain other medications and vitamins. Because of Prilosec's effect on pH in the stomach, Prilosec may alter the absorption of certain other medications, which may alter blood levels and effectiveness of these medications. Because of Prilosec's effect on liver enzymes, Prilosec may alter the process by which certain other medications are eliminated from the body. Prilosec may increase or decrease the effect of certain other medications. Medications that Prilosec may interact with include: certain blood thinners such as Coumadin (warfarin), Pletal (cilostazol), Plavix (clopidogrel); Valium (diazepam); Antabuse (disulfiram); anti-rejections medications used in people with organ transplants, like Neoral (cyclosporine) and Prograf (tactrolimus); Dilantin (phenytoin), a seizure medication; Nizoral (ketoconazole); Vfend (voriconazole); Omnipen (ampicillin); HIV/AIDS medications like Reyataz (atazanavir), Viracept (nelfinavir), and Invirase (saquinavir); and iron supplements like Feosol. New safety information has become available regarding the use of proton pump inhibitors. The safety information includes a possible increased risk of fractures of the hip, wrist and spine with the use of the medications. Studies have found that the greatest risk of fractures were in people who received high doses of proton pump inhibitors or in people who used the medications for 1 year or more. In general, the risks of taking a medication must be weighed against its health benefits. Derek Dore, PharmD
2. Key facts
- It's usual to take Omeran once a day in the morning.
- For severe illness, you can take it twice a day - in the morning and in the evening.
- Common side effects include headaches, diarrhoea and stomach pain. These tend to be mild and go away when you stop taking the medicine.
- If you're self-treating with Omeran, do not take it for longer than 2 weeks without checking with a doctor.
- Omeran is also called by the brand names Losec and Losec MUPS.
Why is this medication prescribed?
Prescription Omeran is used alone or with other medications to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription Omeran is used to treat damage from GERD in adults and children 1 month of age and older. Prescription Omeran is used to allow the esophagus to heal and prevent further damage to the esophagus in adults and children 1 year of age and older with GERD. Prescription Omeran is also used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome in adults. Prescription Omeran is also used to treat ulcers (sores in the lining of the stomach or intestine) and it is also used with other medications to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) Omeran is used to treat frequent heartburn (heartburn that occurs at least 2 or more days a week) in adults. Omeran is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.
Why it’s used
Omeran is used to treat conditions caused by too much acid production in the stomach, such as:
- gastroesophageal reflux disease (GERD)
- erosive esophagitis (acid-related damage to the esophagus, the tube that connects your mouth to your stomach)
- gastric (stomach) ulcers or duodenal ulcers (duodenal ulcers occur in the first part of your small intestine, which is connected to your stomach)
- Zollinger-Ellison syndrome
- stomach infections caused by Helicobacter pylori bacteria.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
Q: Can Prilosec cause high blood pressure?
A: Prilosec (Omeran) belongs to a class of drugs called proton pump inhibitors (PPIs). PPIs decrease or block the production of stomach acid. Prilosec is used to treat the symptoms of gastroesophageal reflux disease (GERD), to promote healing of erosive esophagitis, and to treat or prevent ulcers. Common side effects of Prilosec include gas, stomach pain, nausea, vomiting, diarrhea, and headache. According to the prescribing information for Prilosec, elevated blood pressure has been reported by people taking the drug in post-marketing experience. Post-marketing experience is after the drug has been approved by the U.S. Food and Drug Administration (FDA). In post-marketing experience, patients voluntarily report if they have the side effect. Because it is voluntary, not everyone decides to report if they have the side effect. So, it is hard to know how often the side effect occurs. It is also hard to know if it is caused by the drug or by some other reason. This is different than side effects reported during clinical trials before the drug is approved by the FDA. In clinical trials, researchers have tight control over how side effects are reported and can determine whether they are likely related to the drug or not. So, elevated blood pressure may or may not be caused by Prilosec, but it has been reported in patients taking the drug. See your doctor for proper evaluation of your blood pressure. Your doctor is best able to guide your treatment decisions based on your specific circumstances. Sarah Lewis, PharmD
Is Omeran safe to take if I'm pregnant or breastfeeding?
Use of Omeran in pregnant women has not been adequately evaluated. Omeran should be used during pregnancy only if the benefits justify the unknown risks.
Omeran is excreted in breast milk and potentially could cause adverse effects in the infant.
What should I avoid while taking Omeran?
Omeran can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Q: I have taken Prilosec for 14 days. How long will it take to restore my gastric acid?
A: According to the prescribing information for Prilosec (Omeran), once the drug is discontinued, gastric acid secretion returns gradually over three to five days. Prilosec is categorized as a proton pump inhibitor (PPI) and reduces the amount of stomach acid produced by the body. Prilosec is used to treat the symptoms of gastroesophageal reflux disease (GERD) and other medical conditions that result from too much stomach acid. Prilosec is also used to promote healing of erosive esophagitis and may be used in combination with antibiotics to treat gastric ulcers caused by a Helicobacter pylori (H. pylori) infection. The most commonly reported side effects associated with treatment with Prilosec include headache, abdominal pain, nausea, diarrhea and vomiting. In most cases, Omeran is taken approximately 30 to 60 minutes before a meal. Take Prilosec exactly as directed by your healthcare provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD
By Lynn Marks | Medically Reviewed by Robert Jasmer, MD
Latest Update: 2015-01-09 Copyright © 2014 Everyday Health Media, LLC
What is Omeran used for?
You can buy Omeran 10mg tablets without a prescription over the counter from pharmacies for:
- Relieving heartburn symptoms associated with stomach acid reflux in adults aged 18 years and over.
Q: Does Prilosec cause weight gain and severe night sweats? I have been on it for almost 2 months.
A: According to the package insert, the most common side effects reported in patients treated with Prilosec (Omeran) were headache (6.9%), abdominal pain (5.2%), nausea (4.0%), diarrhea (3.7%), vomiting (3.2%), and gas (2.7%). Weight gain has been reported in clinical practice through voluntary reporting and surveillance systems. A review of medical literature found case reports of night sweats in patients with gastroesophageal reflux disease. The cause of the night sweats and effect of treatment is unknown. For more information, please consult with your health care provider and visit: //www.everydayhealth.com/drugs/prilosec. You are encouraged to report any negative side effects of prescription drugs to your health care practitioner and the U.S. Food and Drug Administration (FDA) by visiting www.fda.gov/medwatch, or by calling 1-800-FDA-1088. Michelle McDermott, PharmD
What brand names are available for Omeran?
Prilosec, Zegerid, Prilosec OTC, Zegerid OTC