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How long will I take it for?
If you bought the medicine yourself from a pharmacy, tell your doctor if you feel no better after taking Omel for 2 weeks.
They may want to do tests to find out what's causing your symptoms or change you to a different medicine.
Depending on your illness or the reason you're taking Omel, you may only need it for a few weeks or months.
Sometimes you might need to take it for longer, even for many years.
Some people don't need to take Omel every day and take it only when they have symptoms.
Once you feel better (often after a few days or weeks), you can stop taking it.
But taking Omel in this way isn't suitable for everyone. Talk to your doctor about what's best for you.
Systemic effects of Omel in the CNS, cardiovascular and respiratory systems have not been found to date. Omel, given in oral doses of 30 or 40 mg for 2 to 4 weeks, had no effect on thyroid function, carbohydrate metabolism, or circulating levels of parathyroid hormone, cortisol, estradiol, testosterone, prolactin, cholecystokinin or secretin.
No effect on gastric emptying of the solid and liquid components of a test meal was demonstrated after a single dose of Omel 90 mg. In healthy subjects, a single I.V. dose of Omel (0.35 mg/kg) had no effect on intrinsic factor secretion. No systematic dose-dependent effect has been observed on basal or stimulated pepsin output in humans.
However, when intragastric pH is maintained at 4.0 or above, basal pepsin output is low, and pepsin activity is decreased.
As do other agents that elevate intragastric pH, Omel administered for 14 days in healthy subjects produced a significant increase in the intragastric concentrations of viable bacteria. The pattern of the bacterial species was unchanged from that commonly found in saliva. All changes resolved within three days of stopping treatment.
The course of Barrett's esophagus in 106 patients was evaluated in a U.S. double-blind controlled study of PRILOSEC 40 mg twice daily for 12 months followed by 20 mg twice daily for 12 months or ranitidine 300 mg twice daily for 24 months. No clinically significant impact on Barrett's mucosa by antisecretory therapy was observed. Although neosquamous epithelium developed during antisecretory therapy, complete elimination of Barrett's mucosa was not achieved. No significant difference was observed between treatment groups in development of dysplasia in Barrett's mucosa and no patient developed esophageal carcinoma during treatment. No significant differences between treatment groups were observed in development of ECL cell hyperplasia, corpus atrophic gastritis, corpus intestinal metaplasia, or colon polyps exceeding 3 mm in diameter.
Q: I'm currently taking Prilosec. Is there any research indicating that Prilosec can cause heart problems?
A: In 2007, the Food and Drug Administration (FDA) issued a Safety Review of Prilosec (Omel) and Nexium (esOmel). The review was prompted by two small, long-term studies that saw an increase in cardiac problems in patients taking either Prilosec or Nexium compared to patients who had surgery. After reviewing all available information, the FDA concluded that the effect was not caused by the drugs themselves and that long-term use of these drugs is not likely to increase the risk of heart problems. The FDA recommends continued use of these products. Consult your healthcare provider for any concerns you may have with Prilosec treatment. You may also find helpful information at //www.everydayhealth.com/drugs/prilosec. Sarah McKenney Lewis, PharmD
Concomitant Gastric Malignancy
Symptomatic response to therapy with Omel does not preclude the presence of gastric malignancy.
How it works
Omel belongs to a class of drugs called proton pump inhibitors (PPIs). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Omel works by decreasing the amount of acid your stomach produces. It does this by blocking a system in the cells of your stomach called the proton pump. The proton pump works in the final step of acid production. When the proton pump is blocked, your stomach makes less acid. This can help decrease your symptoms.
Omel oral capsule doesn’t cause drowsiness. However, it can cause other side effects.
PRILOSEC is indicated for the short-term treatment (4-8 weeks) of erosive esophagitis that has been diagnosed by endoscopy in pediatric patients and adults .
The efficacy of PRILOSEC used for longer than 8 weeks in these patients has not been established. If a patient does not respond to 8 weeks of treatment, an additional 4 weeks of treatment may be given. If there is recurrence of erosive esophagitis or GERD symptoms (eg, heartburn), additional 4-8 week courses of Omel may be considered.
Why it’s used
Omel is used to treat conditions caused by too much acid production in the stomach, such as:
- gastroesophageal reflux disease (GERD)
- erosive esophagitis (acid-related damage to the esophagus, the tube that connects your mouth to your stomach)
- gastric (stomach) ulcers or duodenal ulcers (duodenal ulcers occur in the first part of your small intestine, which is connected to your stomach)
- Zollinger-Ellison syndrome
- stomach infections caused by Helicobacter pylori bacteria.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.