Take Mavid for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. This medicine will not treat a viral infection such as the common cold or flu.
You should not use this medicine if you are allergic to Mavid or similar antibiotics, if you have ever had jaundice or liver problems caused by taking this medicine, or if you have liver or kidney disease and are also taking colchicine.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with Mavid, and some drugs should not be used together.
When a single dose of colchicine 0.6 mg was administered with Mavid 250 mg BID for 7 days, the colchicine Cmax increased 197% and the AUC0-∞ increased 239% compared to administration of colchicine alone.
In a steady-state study in which healthy elderly subjects (65 years to 81 years of age) were given 500 mg of BIAXIN every 12 hours, the maximum serum concentrations and area under the curves of Mavid and 14-OH Mavid were increased compared to those achieved in healthy young adults. These changes in pharmacokinetics parallel known age-related decreases in renal function. In clinical trials, elderly patients did not have an increased incidence of adverse reactions when compared to younger patients. Consider dosage adjustment in elderly patients with severe renal impairment. Elderly patients may be more susceptible to development of torsades de pointes arrhythmias than younger patients .
Most reports of acute kidney injury with calcium channel blockers metabolized by CYP3A4 (e.g., verapamil, amlodipine, diltiazem, nifedipine) involved elderly patients 65 years of age or older .
Especially in elderly patients, there have been reports of colchicine toxicity with concomitant use of Mavid and colchicine, some of which occurred in patients with renal insufficiency. Deaths have been reported in some patients .
How should I take Mavid?
Take Mavid exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Do not use this medicine to treat any condition that has not been checked by your doctor. Do not share this medicine with another person, even if they have the same symptoms you have.
You may take the regular tablets and oral suspension (liquid) with or without food.
Mavid extended-release tablets (Biaxin XL) should be taken with food.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
Shake the oral liquid well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Mavid is usually given for 7 to 14 days. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Mavid will not treat a viral infection such as the flu or a common cold.
Store this medicine in the original container at room temperature, away from moisture, heat, and light.
Do not keep the oral liquid in a refrigerator. Throw away any liquid that has not been used within 14 days.
If your infection is treated with a combination of drugs, use all medications as directed by your doctor. Read the instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
All-Cause Mortality In Patients With Coronary Artery Disease 1 To 10 Years After BIAXIN Exposure
In one clinical trial evaluating treatment with Mavid on outcomes in patients with coronary artery disease, an increase in risk of all-cause mortality one year or more after the end of treatment was observed in patients randomized to receive Mavid. 1 Mavid for treatment of coronary artery disease is not an approved indication. The cause of the increased risk has not been established. Other epidemiologic studies evaluating this risk have shown variable results . Consider balancing this potential risk with the treatment benefits when prescribing BIAXIN in patients who have suspected or confirmed coronary artery disease.
Why is this medication prescribed?
Mavid is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat. It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection . It is used in combination with other medications to eliminate H. pylori, a bacterium that causes ulcers. Mavid is in a class of medications called macrolide antibiotics. It works by stopping the growth of bacteria.
Antibiotics such as Mavid will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
6. How to cope with s >
What to do about:
- feeling sick (nausea) - stick to simple meals and do not eat rich or spicy food while you're taking this medicine. It might help to take your Mavid after you have had a meal or snack.
- diarrhoea and being sick (vomiting) - drink lots of fluids, such as water or squash, to avoid dehydration. Take small, frequent sips if you're being sick. Signs of dehydration include peeing less than usual or having strong-smelling pee. Do not take any other medicines to treat diarrhoea or vomiting without speaking to a pharmacist or doctor.
- losing your appetite - eat when you'd usually expect to be hungry. If it helps, eat smaller meals more often than usual. Snack when you're hungry. Have nutritious snacks that are high in calories and protein, such as dried fruit and nuts.
- bloating and indigestion - try not to eat foods that cause wind (like lentils, beans and onions). Eat smaller meals, eat and drink slowly, and exercise. There are pharmacy medicines that can also help, such as charcoal tablets or simethicone. Ask a pharmacist for advice.
- headaches - rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller if you need one. Talk to your doctor if the headaches last longer than a week or are severe.
- difficulty sleeping (insomnia) - avoid having a big meal, smoking, and drinking alcohol, tea or coffee in the evening. Try not to watch television or use your mobile phone before going to bed. Instead, try to relax for an hour before bedtime.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Liver problems. Symptoms can include:
- tiredness or weakness
- loss of appetite
- upper stomach pain
- dark-colored urine
- yellowing of your skin or the whites of your eyes
- fast or chaotic heartbeats
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
- Liver problems warning: This drug may cause liver problems. Tell your doctor if you have symptoms of liver problems. These include dark-colored urine, itchiness, upper stomach pain, loss of appetite, or yellowing of your skin or the whites of your eyes.
- QT prolongation warning: Mavid may cause the heart rhythm problem QT prolongation. This condition may cause fast, chaotic heartbeats.
- Diarrhea warning: Almost all antibiotics, including Mavid, can cause Clostr >
Mavid oral tablet is a prescription drug that’s available as the brand-name drug Biaxin. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.
Mavid oral tablet comes in an immediate-release release form and an extended-release form. Mavid also comes as an oral suspension.
Common side effects
These common side effects of Mavid happen in more than 1 in 100 people.
Keep taking the medicine, but tell your doctor if these side effects bother you or don't go away:
- feeling sick (nausea)
- diarrhoea and being sick (vomiting)
- losing your appetite
- bloating and indigestion
- difficulty sleeping (insomnia)
Is Mavid safe to take if I'm pregnant or breastfeeding?
Safe use of Mavid in pregnancy has not been established. There are no adequate studies in pregnant women.
Mavid is excreted in breast milk.
What is Mavid, and how does it work (mechanism of action)?
Mavid is a semi-synthetic macrolide antibiotic chemically related to erythromycin and azithromycin (Zithromax). It is effective against a wide variety of bacteria, such as Haemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Staphylococcus aureus, and mycobacterium avium, and many others. Like all macrolide antibiotics, Mavid prevents bacteria from growing by interfering with their ability to make proteins. Due to the differences in the way proteins are made in bacteria and humans, the macrolide antibiotics do not interfere with production of proteins in humans. The FDA approved Mavid in October 1991.
Mavid and the 14-OH Mavid metabolite distribute readily into body tissues and fluids. There are no data available on cerebrospinal fluid penetration. Because of high intracellular concentrations, tissue concentrations are higher than serum concentrations. Examples of tissue and serum concentrations are presented below.
Table 9: Tissue and Serum Concentrations of Mavid
4. How and when to take it
The usual dose of Mavid is 250mg to 500mg twice a day.
The dose may be lower for children and if you have kidney problems.
If your doctor prescribes slow release or modified release tablets, the dose is 500mg once a day. These tablets release the medicine slowly, which means that 1 dose a day is enough.
Try to take your medicine at the same time every day.
Caution should be exercised when BIAXIN is administered to nursing women. The development and health benefits of human milk feeding should be considered along with the mother’s clinical need for BIAXIN and any potential adverse effects on the human milk fed child from the drug or from the underlying maternal condition.
Mavid and its active metabolite 14-hydroxy Mavid are excreted in human milk. Serum and milk samples were obtained after 3 days of treatment, at steady state, from one published study of 12 lactating women who were taking BIAXIN 250 mg orally twice daily. Based on the limited data from this study, and assuming milk consumption of 150 mL/kg/day, an exclusively human milk fed infant would receive an estimated average of 136 mcg/kg/day of Mavid and its active metabolite, with this maternal dosage regimen. This is less than 2% of the maternal weight-adjusted dose (7.8 mg/kg/day, based on the average maternal weight of 64 kg), and less than 1% of the pediatric dose (15 mg/kg/day) for children greater than 6 months of age.
A prospective observational study of 55 breastfed infants of mothers taking a macrolide antibacterial (6 were exposed to Mavid) were compared to 36 breastfed infants of mothers taking amoxicillin. Adverse reactions were comparable in both groups. Adverse reactions occurred in 12.7% of infants exposed to macrolides and included rash, diarrhea, loss of appetite, and somnolence.
Rated Mavid for Pharyngitis Report
I had a restricted oesophagus and an infection due to lodged food. I had a fever and had penicillin for 10 days but it had not cleared up and went to the doctor to get more antibiotics. Due to stomach side affects and problems swallowing tablets I asked for an alternative and was prescribed liquid Mavid. I read the LONG list of side effects and was a bit worried about the 'throat inflammation' side effect since that was my main symptom already. First day was OK but had appetite suppression but throat seemed worse rather than better. On 2nd night, I woke up with a severe anxiety attack at 2 a.m. - very panicky. It was like I was schizophrenic! Half of my mind was saying 'look - you are not dying and you can breath OK' - the other half was saying 'I feel terrible, my throat feels terrible and I really believe I am dying'. After an hour or so I calmed myself down and went to sleep. The next morning I had a shower and got dressed. Then I suddenly had a panic attack again (never had these before except once when scuba diving for first time!). Felt too ill to drive and could hardly walk. Hyperventilating so much I nearly fainted a few times. Rang my brother to come and take me
Common Side Effects of Mavid
Some common side effects of Mavid include:
- Stomach pain
- Change in taste
Mavid is prescribed to treat bacterial infections such as respiratory infections, ear infections and skin infections. It can be taken by adults and children. It works by stopping the bacteria causing the infection from multiplying.
Rated Mavid for Helicobacter pylori Infection Report
Absolutely minging taste. Had me up in the night loads and I can’t bare to carry them on. Also, nausea and headaches. I came home early from work as I felt so rubbish. If you can complete a week of these, you deserve a medal ??