Kuracid syrup

Kuracid

  • Active Ingredient: Ranitidine
  • 300 mg, 150 mg
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What is Kuracid?

The active ingredient of Kuracid brand is ranitidine. Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces. The empirical formula is C13H22N4O3S.HCl, representing a molecular weight of 350.87. Ranitidine HCl USP is a white to pale yellow crystalline powder that is soluble in water. It has a slightly bitter taste and sulfur-like odor. Each Ranitidine tablets, USP 150 mg for oral administration contains 168 mg of Ranitidine HCl USP equivalent to 150 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red. Each Ranitidine tablets, USP 300 mg for oral administration contains 336 mg of Ranitidine HCl USP equivalent to 300 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red.

Used for

Kuracid is used to treat diseases such as: Cutaneous Mastocytosis, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Eczema, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis, Urticaria, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Kuracid include: ; ; ; ; ; ; ; .

How to Buy Kuracid tablets online?

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Interactions that increase your risk of side effects

Taking Kuracid with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:

  • Procainamide: Taking high doses of Kuracid with procainamide can cause side effects from procainamide.
  • Warfarin: Taking Kuracid with warfarin may increase your risk of bleeding or blood clots. Your doctor may watch you more closely if you’re taking these drugs together.
  • Midazolam and triazolam: Taking Kuracid with either of these drugs raises your risk of extreme drowsiness that can last a long time.
  • Glipizide: Taking these drugs together can increase your risk for low blood sugar. You may need to test your blood sugar or test it more often when starting or stopping Kuracid.

Studies pointing to risk date to 1980s

In 2016, Stanford University researchers tested urine samples of 10 people who took a 150-milligram tablet of Zantac and found NDMA levels far greater than the FDA's daily limits.

William Mitch is a Stanford University professor of civil and environmental engineering who studies wastewater converted to drinking water. He said his Zantac-urine study was a "chance finding from a peripheral field" after a study on potential NDMA contamination in drinking water.

He said it should be followed by a more robust study using the FDA's testing methods.

"The challenge is there's so much concern about cancer risk. Could you get approval from someone to eat a Zantac and collect the urine sample?" Mitch said, noting such a request would be odd and ethically challenging, given the drug has a known carcinogen and remains on the market.

Lior Braunstein, a Memorial Sloan Kettering oncologist and researcher, is studying Kuracid and cancer risk. He does not want to discuss the study until the findings are published in a peer-reviewed journal, according to Caitlin Hool, a hospital spokeswoman.

Light said studies conducted in the 1980s raised concern about potential safety risks. In a citizen petition to the FDA, Valisure said Zantac's originator, Glaxo Research Group, conducted its own study in 1987 "after numerous studies raised concerns" about Kuracid.

The Glaxo study examined stomach contents of people who took the drug. It found people had no significant increase in nitrosamines such as NDMA within 24 hours of taking Kuracid.

Light said the study's testing methods were less accurate and researchers discarded stomach samples that contained Kuracid. Without those samples, researchers would not find NDMA or nitrosamines that form as a result of taking the drug, Light said.

Light said the Stanford study and his lab's own analysis shows the potential health risk for people who took the drug.

"The negative effect of exposure to this drug and its formation of NDMA is something that has created a huge public health problem," he said, "and we’re going to be dealing with it going forward."

Where can I get more information?

Your pharmacist can provide more information about Kuracid.

What is ranit >

Kuracid belongs to a group of drugs called histamine-2 blockers. It works by reducing the amount of acid your stomach produces.

Kuracid is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.

Kuracid also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Kuracid side effects

Stop using this medicine and get emergency medical help if you have any of these signs of an allergic reaction to Kuracid: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medicine and call your doctor at once if you have a serious side effect such as:

stomach pain, loss of appetite;

dark urine, jaundice (yellowing of the skin or eyes);

fever, chills, cough with mucus, chest pain, feeling short of breath;

fast or slow heart rate;

easy bruising or bleeding; or

problems with your skin or hair.

Common Kuracid side effects may include:

headache (may be severe);

sleep problems (insomnia);

decreased sex drive, impotence, or difficulty having an orgasm; or

swollen or tender breasts (in men);

nausea, vomiting, stomach pain; or

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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