Klariger tablets

Klariger

  • Active Ingredient: Clarithromycin
  • 500 mg, 250 mg
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What is Klariger?

The active ingredient of Klariger brand is clarithromycin. Clarithromycin is a macrolide antibiotic. Clarithromycin fights bacteria in your body. Clarithromycin is a white to off-white crystalline powder. It is soluble in acetone, slightly soluble in methanol, ethanol, and acetonitrile, and practically insoluble in water. Clarithromycin tablets, USP are intended for oral administration and contain 250 mg or 500 mg of Clarithromycin, USP. In addition, each Clarithromycin tablet contains the following inactive ingredients: croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, talc, and titanium dioxide.

Used for

Klariger is used to treat diseases such as: Bacterial Endocarditis Prevention, Bronchitis, Dental Abscess, Follicular Lymphoma, Helicobacter Pylori Infection, Legionella Pneumonia, Mycobacterium avium-intracellulare, Prophylaxis, Mycobacterium avium-intracellulare, Treatment, Mycoplasma Pneumonia, Nongonococcal Urethritis, Otitis Media, Pertussis, Pertussis Prophylaxis, Pharyngitis, Pneumonia, Sinusitis, Skin and Structure Infection, Skin or Soft Tissue Infection, Strep Throat, Tonsillitis/Pharyngitis, Toxoplasmosis, Upper Respiratory Tract Infection.

Side Effect

Possible side effects of Klariger include: feeling, seeing, or hearing things that are not there; skin rash and itching; clay-colored stools; chest pain or discomfort; Alterations of sense of smell; severe mood or mental changes.

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Rated Klariger for Tonsillitis/Pharyngitis Report

I have a throat, sinus & ear infection all at once. My first med taken was zpack which helped but didn’t make the infection fully go away because I stopped taking the med once I was feeling better which cause the infection to come back but this time it was resistant to the antibiotics. Next, I tried Amoxicillin and it helped but didn’t fully take away the infection. After that I was prescribed Augmentin, which did nothing. Finally, I went to an ENT and was prescribed Klariger and steroids to get rid of the infection and dry, swollen soft palate. After 2 days of taking this med I was so excited because it seems like it is working the best but now on day 3, I am having terrible anxiety, heart palpitations, feels like my heart keeps stopping & short episodes of blacking out. I can not finish taking this drug because of it’s terrifying side effects. It’s a shame because my swelling is almost gone and throat and ear pain has decreased major.

Outcome and Management

The minor serum aminotransferase elevations that appear during therapy with Klariger are usually benign, asymptomatic and resolve rapidly whether or not Klariger is stopped. The acute hepatic injury with jaundice, however, can be prolonged and troublesome and lead to loss of intrahepatic bile ducts and vanishing bile duct syndrome. Rare instances of fatality from Klariger induced liver disease have been reported. It is unclear whether there is cross sensivity to hepatic injury about the different macrolide antibiotics, but after severe injury from one macrolide, it is prudent to avoid use of the others.

Carcinogenesis, Mutagenesis, Impairment Of Fertility

The following in vitro mutagenicity tests have been conducted with Klariger:

  • Salmonella/Mammalian Microsomes Test
  • Bacterial Induced Mutation Frequency Test
  • In Vitro Chromosome Aberration Test
  • Rat Hepatocyte DNA Synthesis Assay
  • Mouse Lymphoma Assay
  • Mouse Dominant Lethal Study
  • Mouse Micronucleus Test

All tests had negative results except the in vitro chromosome aberration test which was positive in one test and negative in another. In addition, a bacterial reverse-mutation test (Ames test) has been performed on Klariger metabolites with negative results.

Ergot Alkaloids

Concomitant administration of Klariger and ergotamine or dihydroergotamine is contraindicated .

Embryofetal Toxicity

Klariger should not be used in pregnant women except in clinical circumstances where no alternative therapy is appropriate. If BIAXIN is used during pregnancy, or if pregnancy occurs while the patient is taking this drug, the patient should be apprised of the potential hazard to the fetus. Klariger has demonstrated adverse effects on pregnancy outcome and/or embryo-fetal development in monkeys, rats, mice, and rabbits at doses that produced plasma levels 2 times to 17 times the serum levels achieved in humans treated at the maximum recommended human doses .

Hepatotoxicity

Hepatic dysfunction, including increased liver enzymes, and hepatocellular and/or cholestatic hepatitis, with or without jaundice, has been reported with Klariger. This hepatic dysfunction may be severe and is usually reversible. In some instances, hepatic failure with fatal outcome has been reported and generally has been associated with serious underlying diseases and/or concomitant medications. Symptoms of hepatitis can include anorexia, jaundice, dark urine, pruritus, or tender abdomen. Discontinue BIAXIN immediately if signs and symptoms of hepatitis occur.

Important Information

Take Klariger for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. This medicine will not treat a viral infection such as the common cold or flu.

You should not use this medicine if you are allergic to Klariger or similar antibiotics, if you have ever had jaundice or liver problems caused by taking this medicine, or if you have liver or kidney disease and are also taking colchicine.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with Klariger, and some drugs should not be used together.

How it works

Klariger belongs to a class of drugs called antibiotics (macrolides). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Klariger works by stopping the bacteria that are causing an infection from multiplying.

This drug should only be used to treat or prevent bacterial infections. It shouldn’t be used to treat viruses such as the common cold.

Klariger oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

How should I take Klariger?

Take Klariger exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not use this medicine to treat any condition that has not been checked by your doctor. Do not share this medicine with another person, even if they have the same symptoms you have.

You may take the regular tablets and oral suspension (liquid) with or without food.

Klariger extended-release tablets (Biaxin XL) should be taken with food.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Shake the oral liquid well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Klariger is usually given for 7 to 14 days. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Klariger will not treat a viral infection such as the flu or a common cold.

Store this medicine in the original container at room temperature, away from moisture, heat, and light.

Do not keep the oral liquid in a refrigerator. Throw away any liquid that has not been used within 14 days.

If your infection is treated with a combination of drugs, use all medications as directed by your doctor. Read the instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Klariger only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 21.01.

Rated Klariger for Tonsillitis Report

I was on phenoxypenicillin but it failed so was given Klariger I’m 3 days into treatment so far feels like my throat is clearing up but I get side affects from this medication I get headaches that start when the tablet starts kicking in and the headache lasts for a long time. When I first took the tablet I felt very sick and had stomach cramps but that has not repeated.

Is Klariger safe to take if I'm pregnant or breastfeeding?

Safe use of Klariger in pregnancy has not been established. There are no adequate studies in pregnant women.

Klariger is excreted in breast milk.

2. Key facts

  • It's usual to take Klariger twice a day: once in the morning and once in the evening.
  • Some people take slow-release Klariger tablets. These are taken once a day.
  • For most infections, you should feel better within a few days.
  • The most common side effects of Klariger are feeling or being sick, stomach cramps, and diarrhoea.
  • You can drink alcohol while taking Klariger.
  • Clarithromcyin is also called by the brand names Clarie XL, Klaricid, Klaricid XL and Xetinin XL.

What is Klariger?

Klariger is a macrolide antibiotic that fights bacteria in your body.

Klariger is used to treat many different types of bacterial infections affecting the skin and respiratory system.

Klariger is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

What should I tell my health care provider before taking Klariger?

Before taking Klariger, tell your health care provider:

  • If you are allergic to Klariger or any other medicines.
  • About any medical conditions you have or have had.
  • About anything that could affect your ability to take medicines, such as difficulty swallowing or remembering to take pills. A liquid form of Klariger is available for people who have difficulty swallowing pills.
  • If you are pregnant or plan to become pregnant. Klariger should not be used during pregnancy except when there are no other treatment options. Talk to your health care provider about the risks of taking Klariger during pregnancy.
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Klariger may affect the way other medicines or products work, and other medicines or products may affect how Klariger works. Ask your health care provider if there are interactions between Klariger and the other medicines you take.

Ask your health care provider about possible side effects from Klariger. Your health care provider will tell you what to do if you have side effects.


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