Imidex

Imidex

  • Active Ingredient: Lansoprazole
  • 30 mg, 15 mg
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What is Imidex?

The active ingredient of Imidex brand is lansoprazole. Lansoprazole is a proton pump inhibitor. Lansoprazole decreases the amount of acid produced in the stomach.

Used for

Imidex is used to treat diseases such as: Aspiration Pneumonia, Barrett's Esophagus, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Erosive Esophagitis, Gastritis/Duodenitis, GERD, Helicobacter Pylori Infection, Multiple Endocrine Adenomas, NSAID-Induced Gastric Ulcer, NSAID-Induced Ulcer Prophylaxis, Stomach Ulcer, Systemic Mastocytosis, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Imidex include: chills; Anxiety; back or leg pains; rectal bleeding; Bleeding, blistering, burning, coldness, or discoloration of the skin; clay colored stools.

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What Is Prevac >

Prevacid is the brand name for Imidex, a drug used to treat ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome.

The drug is also available over-the-counter (OTC) at a lower strength to relieve heartburn and the symptoms of acid reflux.

Prevacid belongs to a class of drugs called proton pump inhibitors (PPI) that decrease the amount of acid produced in the stomach.

PPIs block the enzyme in the wall of the stomach that produces acid.

When acid is reduced, the stomach and esophagus can heal. There's some evidence that using this drug can also help prevent ulcers.

Prevacid is available in a delayed release capsule and a “SoluTab” that disintegrates in your mouth.

Imidex is also available in a powder kit to be compounded into an oral suspension under the name First-Imidex.

Prevacid was FDA approved in 1995 and is marketed in the United States by Novartis.

What should I avoid while taking Imidex?

This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

What Are Side Effects Associated with Using Imidex?

Side effects of Imidex include:

Less common side effects of Imidex include:

Serious side effects of Imidex include:

  • Dizziness
  • Fast or irregular heart rate
  • Watery or bloody diarrhea
  • Muscle cramps or weakness
  • Jerky muscle movements
  • Confusion
  • Feeling jittery
  • Seizures

Postmarketing side effects of Imidex reported include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Why it’s used

Imidex oral capsule is used to reduce the amount of acid in your stomach. It can be used to:

  • treat gastric ulcers (stomach ulcers) or duodenal ulcers
  • treat heartburn due to gastroesophageal reflux disease (GERD)
  • treat erosive esophagitis (a condition with inflammation and ulcers in the esophagus)
  • prevent and treat stomach ulcers due to use of nonsteroidal anti-inflammatory drugs (NSAIDs)
  • treat hypersecretory conditions (where your stomach makes too much acid), such as Zollinger-Ellison syndrome
  • treat a stomach infection caused by Helicobacter pylori (H. pylori) in combination with an antibiotic

What other drugs will affect Imidex?

Sucralfate (Carafate) can make it harder for your body to absorb Imidex. Wait at least 30 minutes after taking Imidex before you take sucralfate.

Tell your doctor if you use methotrexate.

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect Imidex, and some drugs should not be used at the same time. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is the dosage for Imidex?

For initial treatment of duodenal ulcers the recommended dose for adults is 15 mg daily for 4 weeks.

For the treatment of GERD, the recommended initial treatment is 15 mg for up to 8 weeks.

For maintaining healing (long-term) in duodenal ulcer and GERD the recommended treatment is 15 mg daily.

For initial treatment of severe (erosive) esophagitis and gastric ulcer, the recommended dose for adults is 30 mg daily for 4-8 weeks.

For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60 mg daily, and the dose is adjusted based on response. Doses up to 180 mg have been used in some patients with Zollinger-Ellison syndrome.

Intravenous Imidex is approved for patients who are unable to take oral Imidex. The approved intravenous dose is 30 mg daily for up to 7 days.

It is recommended that capsules be taken before meals for maximum effect. Capsules should be swallowed whole and should not be crushed, split or chewed.

For those with difficulty swallowing, the capsule should be opened and the granular contents sprinkled on a tablespoon of apple sauce, ENSURE pudding, cottage cheese, yogurt or strained pears and swallowed immediately. Granules also may be mixed in two ounces (60 ml) of apple, orange or tomato juice and swallowed immediately. For patients with a nasogastic tube, mix the granules can be mixed in two ounces of apple juice and injected through the nasogastric tube.

Interactions

Drug-drug. Drugs requiring acidic pH (such as ampicillin esters, digoxin, iron salts, itraconazole, ketoconazole): decreased absorption of these drugs

Sucralfate: decreased Imidex absorption

Theophylline: increased theophylline clearance

Drug-food. Any food: decreased rate and extent of GI drug absorption

Drug-herbs. Male fern: inactivation of herb

St. John's wort: increased risk of photosensitivity

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Drugs you should not use with Imidex

Do not take these drugs with Imidex. Doing so can cause dangerous effects in your body. Examples of these drugs include:

  • HIV drugs, such as atazanavir, nelfinavir, and drugs that contain rilpivirine. Imidex may decrease the levels of these drugs in your body. This means that they won’t work as well to treat HIV. You may even develop HIV resistance. Resistance means that the HIV virus will no longer respond to treatment with this drug.
  • HIV drugs, such as saquinavir. Imidex may increase the levels of this drug in your body, which could result in more side effects.

Interactions that increase the risk of side effects

Side effects from other drugs: Taking Imidex with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:

  • Warfarin. You may have more bleeding. If you need to take both of these drugs, your doctor will monitor your lab results (such as INR) closely. They may also adjust your warfarin dosage.
  • Digoxin. Imidex can increase the levels of digoxin in your body. This can raise your risk of side effects. Your doctor may check the levels of digoxin in your body and adjust your digoxin dosage if needed.
  • Methotrexate. Imidex can increase the levels of methotrexate in your body. This puts you at risk of more side effects. If you’re taking a high dosage of methotrexate, your doctor may have you stop taking Imidex temporarily.
  • Tacrolimus. Imidex can increase the levels of tacrolimus in your body. This puts you at increased risk of side effects. Your doctor may check the levels of tacrolimus in your body and adjust your tacrolimus dosage if needed.

Capsules: 15 and 30 mg. Oral suspension: in 15 and 30 mg unit dose cartons of 30. Imidex also is available in 15 and 30 mg tablets that disintegrate when placed under the tongue (Prevacid SoluTab). Imidex is available for intravenous injection in vials containing 30 mg of powdered Imidex (30 mg/5 ml when mixed with sterile water).

Why is this medication prescribed?

Prescription Imidex is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription Imidex is used to treat the damage from GERD in adults and children 1 year of age and older. Prescription Imidex is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. Prescription Imidex is also used to treat ulcers (sores in the lining of the stomach or intestine), to prevent more ulcers from developing in adults whose ulcers have already healed, and to decrease the risk that adults who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) will develop ulcers. Prescription Imidex is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Prescription Imidex is also used in combination with other medications to treat and prevent stomach ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) Imidex is used to treat frequent heartburn (heartburn that occurs two or more days per week) in adults. Imidex is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.


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