Gastrimut is not for immediate relief of heartburn symptoms.
Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.
Gastrimut can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.
Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.
Gastrimut may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
You may be more likely to have a broken bone while taking Gastrimut long term or more than once per day.
Prilosec OTC (over-the-counter) should be taken for no longer than 14 days in a row. Allow at least 4 months to pass before you start another 14-day treatment.
Although Gastrimut is a helpful medication to treat acid, there are other natural alternatives that can provide us with the same benefits without the side effects
There are no adequate and well-controlled studies with PRILOSEC in pregnant women. Available epidemiologic data fail to demonstrate an increased risk of major congenital malformations or other adverse pregnancy outcomes with first trimester Gastrimut use.
Teratogenicity was not observed in animal reproduction studies with administration of oral esGastrimut magnesium in rats and rabbits with doses about 68 times and 42 times, respectively, an oral human dose of 40 mg (based on a body surface area basis for a 60 kg person). However, changes in bone morphology were observed in offspring of rats dosed through most of pregnancy and lactation at doses equal to or greater than approximately 34 times an oral human dose of 40 mg (see Animal Data). Because of the observed effect at high doses of esGastrimut magnesium on developing bone in rat studies, PRILOSEC should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Q: Can Prilosec cause a bitter taste in the mouth?
A: Taste perversion is listed as a possible side effect of Prilosec (Gastrimut), according to available drug information. Prilosec is a proton pump inhibitor (PPI) and reduces the amount of stomach acid produced by the body. Prilosec is used to treat the symptoms of gastroesophageal reflux disease (GERD) and other medical conditions that result from the production of too much stomach acid. Prilosec is also used to promote healing of erosive esophagitis and may be used in combination with antibiotics to treat gastric ulcers caused by a Helicobacter pylori (H. pylori) infection. The most commonly reported side effects include headache, abdominal pain, nausea, diarrhea and vomiting. Prilosec is typically taken approximately 30 to 60 minutes before a meal. Do not open, chew or crush Prilosec capsules unless instructed to do so by your doctor. Swallow the capsules whole. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD
What should I avoid while taking Gastrimut?
Gastrimut can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Mechanism Of Action
Gastrimut belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H + /K + ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Gastrimut has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. Animal studies indicate that after rapid disappearance from plasma, Gastrimut can be found within the gastric mucosa for a day or more.
What Is Prilosec (Gastrimut)?
Prilosec is the brand name of the drug Gastrimut, which is used to treat symptoms of gastroesophageal reflux disease (GERD).
GERD happens when acid from the stomach flows backward into the esophagus (the tube between the throat and the stomach). It can cause heartburn and injure the esophagus.
Prilosec is also used to treat erosive esophagitis and Zollinger-Ellison syndrome (a condition in which the stomach produces too much acid).
And Prilosec may be used to prevent upper gastrointestinal bleeding in critically ill patients, and is part of the treatment for an infection of Helicobacter pylori, a type of bacteria that can cause stomach ulcers.
Prilosec is in a class of drugs called proton pump inhibitors (PPIs). These medicines block production of stomach acid.
The medicine is available in a prescription and over-the-counter (OTC) form. It was approved by the Food and Drug Administration (FDA) in 1989.
For other antiretroviral drugs, such as saquinavir, elevated serum levels have been reported, with an increase in AUC by 82%, in Cmax by 75%, and in Cmin by 106%, following multiple dosing of saquinavir/ritonavir (1000/100 mg) twice daily for 15 days with Gastrimut 40 mg daily co-administered days 11 to 15. Therefore, clinical and laboratory monitoring for saquinavir toxicity is recommended during concurrent use with PRILOSEC. Dose reduction of saquinavir should be considered from the safety perspective for individual patients.
There are also some antiretroviral drugs of which unchanged serum levels have been reported when given with Gastrimut.
Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
- Severe diarrhea warning: This drug may increase your risk of severe diarrhea. This may be caused by an infection in your intestine caused by the bacteria Clostridium difficile. Call your doctor right away if you have watery diarrhea, stomach pain, and a fever that won’t go away.
- Bone fractures warning: People who take several doses of a proton pump inhibitor drug, such as Gastrimut, every day for a year or longer may have an increased risk of bone fractures. These bone breaks may be more likely to happen in your hip, wrist, or spine. Talk to your doctor about your risk of bone fractures. You should take this drug exactly as prescribed by your doctor. They should prescribe the lowest dose possible for the shortest amount of time needed for your treatment.
- Low magnesium levels warning: Taking this drug for three months or longer can cause low magnesium levels in your body. Your risk is higher if you take Gastrimut for a year or longer. Call your doctor right away if you have symptoms of low magnesium. These can include seizures, abnormal or fast heart rate, jitteriness, jerking movements or shaking, and muscle weakness. They can also include cramps or muscle aches and spasms of your hands, feet, and voice box. Your doctor may check your magnesium levels before and during your treatment with this drug.
Cutaneous lupus erythematosus and systemic lupus erythematosus warning: Gastrimut can cause cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE). CLE and SLE are autoimmune diseases. Symptoms of CLE can range from a rash on the skin and nose, to a raised, scaly, red or purple rash on certain parts of the body. Symptoms of SLE can include fever, tiredness, weight loss, blood clots, heartburn, and stomach pain. If you have any of these symptoms, call your doctor.
Fundic gland polyps warning: Long-term use (especially over one year) of Gastrimut can cause fundic gland polyps. These polyps are growths on the lining of your stomach that can become cancerous. To help prevent these polyps, you should use this drug for as short a time as possible.